Table 3 Healthcare resource utilization pre- and post-ALIS initiation (N = 331)

Hospitalizations^a

 Proportion of patients with hospitalizations, n (%)

  All-cause

93 (28.1)

119 (35.9)

88 (26.6)

0.0033^b

76 (23.0)

 < 0.0001^b

  Respiratory disease–related

67 (20.2)

89 (26.9)

64 (19.3)

0.0061^b

51 (15.4)

 < 0.0001^b

 Number of hospitalizations per patient per 6 months, mean ± SD

  All-cause

0.9 ± 1.4

1.2 ± 1.8

0.7 ± 1.2

0.0002^c

0.7 ± 1.4

 < 0.0001^c

  Respiratory disease–related

0.7 ± 1.2

1.0 ± 1.6

0.6 ± 1.0

0.0002^c

0.6 ± 1.2

0.0001^c

 LOS (per hospital admission), mean ± SD, days

  All-cause

4.7 ± 4.1

6.2 ± 4.9

3.9 ± 3.8

0.0004^c

4.9 ± 5.6

0.0055^c

  Respiratory disease–related

4.9 ± 4.1

6.2 ± 4.5

4.4 ± 4.0

0.0116^c

5.2 ± 5.7

0.0209^c

ED visits

 Proportion of patients with ED visits, n (%)

  All-cause

41 (12.4)

39 (11.8)

37 (11.2)

0.7576^b

29 (8.8)

0.1573^b

  Respiratory disease–related

15 (4.5)

17 (5.1)

10 (3.0)

0.0896^b

18 (5.4)

0.8415^b

 Number of ED visits per patient per 6 months, mean ± SD

  All-cause

0.6 ± 1.1

0.6 ± 1.2

0.7 ± 1.7

0.3202^c

0.5 ± 1.1

0.1455^c

  Respiratory disease–related

0.5 ± 1.2

0.5 ± 0.9

0.4 ± 1.3

0.3619^c

0.5 ± 0.9

0.7945^c

Outpatient office visits

 Proportion of patients with outpatient visits, n (%)

  All-cause

294 (88.8)

296 (89.4)

289 (87.3)

0.1779^b

285 (86.1)

0.0934^b

  Respiratory disease–related

193 (58.3)

219 (66.2)

196 (59.2)

0.0088^b

179 (54.1)

 < 0.0001^b

 Number of outpatient visits per patient per 6 months, mean ± SD

  All-cause

6.2 ± 7.5

7.3 ± 8.6

7.4 ± 13.0

0.0071^c

6.8 ± 12.8

0.0028^c

  Respiratory disease–related

2.4 ± 3.3

3.3 ± 5.0

3.0 ± 9.4

 < 0.0001^c

2.2 ± 3.5

 < 0.0001^c