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Table 1 Participants’ demographic and baseline clinical characteristics

From: Effects of less invasive surfactant administration versus intubation-surfactant-extubation on bronchopulmonary dysplasia in preterm infants with respiratory distress syndrome: a single-center, retrospective study from China

Variables

LISA group

(n = 46)a

InSurE group (n = 102)a

P-value

Gestational age (weeks), mean (SD)

29.5 ± 1.4

29.1 ± 1.5

0.185

Birth weight, median (IQR), g

1245.0 (1067.5–1399.5)

1130.0 (1030.0–1402.5)

0.349

Weight at discharge, median (IQR), g

2440.0 (2267.5–2900.0)

2340.0 (2117.5–3140.0)

0.824

Male

25 (54.3)

67 (65.7)

0.188

Caesarean

37 (80.4)

76 (74.5)

0.432

Multiple fetuses

12 (26.1)

25 (24.5)

0.838

Small for gestational age

2 (4.3)

5 (4.9)

1.000

Apgar score at 5 min, median (IQR)

9 (9–10)

9 (9–10)

0.177

Maternal complications

   

Premature rupture of membranes

14 (30.4)

37 (36.3)

0.489

Gestational diabetes

11 (23.9)

33 (32.4)

0.298

Gestational hypertension

12 (26.1)

34 (33.3)

0.378

Placental abruption

5 (10.9)

16 (15.7)

0.437

Complete antenatal corticosteroids

28 (60.9)

61 (59.8)

0.902

Time from birth to surfactant administration median (IQR), min

113.5 (93.8–241.8)

123.5 (80.0–184.5)

0.535

PEEP prior to surfactant administration median (IQR)

6.0 (6.0–7.0)

6.0 (6.0–7.0)

0.894

FiO2 prior to surfactant administration median (IQR)

34 (30–40)

35 (30–40)

0.553

  1. LISA, less invasive surfactant administration; InSurE, intubate-surfactant-extubation; n, number; wk, weeks; g, grams; SD, standard deviation; IQR, interquartile range; PEEP, positive end-expiratory pressure
  2. aData are expressed as numbers (%) unless otherwise indicated