Table 1 Patients’ baseline characteristics in the primary cohort and validation cohort
Variables | Primary cohort (n = 540) | Validation cohort (n = 228) |
|---|---|---|
Demographic characteristics | ||
Age, years | 68 (58.71) | 67 (56.81) |
Gender, n (%) | ||
Male | 298 (55.19) | 136 (59.65) |
Female | 242 (44.81) | 92 (40.35) |
Mechanical ventilation, n (%) | 342 (63.33) | 126 (55.26) |
Comorbidities, n (%) | ||
Hypertension | 6 (1.11) | 1 (0.44) |
Diabetes | 3 (0.56) | 1 (0.44) |
Chronic heart failure | 18 (3.33) | 8 (3.51) |
Chronic liver disease | 1 (0.19) | 0 |
Laboratory parameters, [median, (IQR)] | ||
White blood cell (109/L) | 15.19 (11.18) | 14.65 (10.18) |
Hemoglobin (g/dL) | 9.96 (9.10) | 10.08 (8.10) |
Platelet (109/L) | 195 (116.262) | 200 (106.161) |
Bilirubin (umol/L) | 2.55 (1.3) | 2.56 (0.2) |
Albumin (g/dL( | 3.14 (3.4) | 3.23 (3.4) |
Potassium (mmol/L) | 4.25 (4.5) | 4.23 (4.5) |
Sodium (mmol/L) | 139 (136.142) | 139 (135.142) |
Bicarbonate (mmol/L) | 20.84 (16.25) | 21.67 (18.25) |
Lactate (mmol/L) | 2.94 (1.3) | 2.81 (1.3) |
Creatinine (mg/dL) | 2.05 (1.3) | 1.76 (1.2) |
BUN (mg/dL) | 40.42 (19.54) | 35.14 (19.45) |
SaO2 | 94 (93.97) | 96 (95.97) |
PaO2 | 145 (77.166) | 139 (79.166) |
Vital signs | ||
Heart rates (/min) | 95 (78.120) | 93 (73.116) |
DBP (mmHg) | 59 (53.63) | 58 (54.62) |
SBP (mmHg) | 114 (102.121) | 117 (108.123) |
MAP (mmHg) | 70.92 (64.83) | 72 (61.82) |
Severity scores | ||
SOFA | 5 (3.8) | 6 (3.8) |
SAPSII | 51 (40.60) | 49 (38.59) |