Skip to main content

Table 2 Clinical features and laboratory data of patients with AECOPD (n = 413)

From: Risk factors for hyponatremia in acute exacerbation chronic obstructive pulmonary disease (AECOPD): a multicenter cross-sectional study

 

Normonatremia (n = 323)

Hyponatremia (n = 90)

Statistical values

P value

Fever [n, (%)]

21 (6.5%)

13 (14.4%)

5.88

0.015

WBC (× 109/L)

7.53 ± 3.35

8.36 ± 4.07

 − 1.99

0.047

NS (× 109/L)*

4.96 (3.58, 7.42)

5.6 (4.21, 8.03)

 − 2.20

0.028

LYM (× 109/L)

1.47 ± 0.81

1.26 ± 0.56

2.24

0.026

EOS (× 109/L)*

0.16 (0.07, 0.31)

0.1 (0.03, 0.26)

 − 2.21

0.027

NS%

74.82 ± 11.59

78.94 ± 10.72

 − 3.03

0.003

LYM%*

20.59 (14.36, 29.09)

18.19 (10.77, 22.62)

 − 3.14

0.002

EOS%*

2.48 (0.86, 5.09)

1.66 (0.33, 3.82)

 − 2.31

0.021

NLR*

3.64 (2.31, 5.66)

4.31 (3.33, 8.15)

 − 3.09

0.002

RBC (× 1012/L)

4.47 ± 0.61

4.36 ± 0.68

1.50

0.136

HB (g/L)

133.89 ± 15.83

130.82 ± 18.53

1.57

0.118

HCT (L/L)

40.73 ± 4.64

40.03 ± 5.25

1.24

0.217

PLT (× 109/L)

198.65 ± 69.98

208.21 ± 79.46

 − 1.11

0.267

PCT (ng/ml)*

0.05 (0.03, 0.08)

0.07 (0.04, 0.15)

 − 4.54

0.000

CRP (mg/ml)

22.08 ± 35.74

26.77 ± 38.68

 − 1.08

0.280

ESR (mm/first hour)

21.67 ± 17.51

34.17 ± 23.45

 − 5.52

0.000

ABG

PH*

7.43 (7.41, 7.45)

7.45 (7.42, 7.47)

 − 2.62

0.009

PaCO2 (mmHg)*

40 (37, 46)

38.5 (34, 46)

 − 1.73

0.083

PaO2 (mmHg)

75.91 ± 15.11

75.89 ± 16.04

0.01

0.992

AB (mmol/L)

28.11 ± 5.14

28.05 ± 5.62

0.10

0.920

SB (mmol/L)

27.39 ± 3.00

27.56 ± 3.25

 − 0.46

0.648

AG

10.94 ± 4.89

12.14 ± 4.71

 − 2.08

0.039

Serum Na+ (mmol/L)*

139.60 (137.90, 141.45)

131.75 (129.43, 133.57)

 − 14.52

0.000

Serum K+ (mmol/L)

3.95 ± 0.41

3.93 ± 0.54

 − 0.68

0.500

Serum Ca2+ (mmol/L)

2.25 ± 0.14

2.21 ± 0.18

2.24

0.026

Serum Mg2+ (mmol/L)

0.86 ± 0.11

0.83 ± 0.09

2.94

0.003

ALB (g/L)*

38.50 (36.10, 41.10)

36.9 (33.65, 40.25)

 − 2.80

0.005

BUN (mmol/L)

6.44 ± 2.31

6.36 ± 2.66

0.26

0.793

Cr (μmol/L)

73.32 ± 21.11

72.57 ± 30.93

0.27

0.790

ALT (U/L)

22.38 ± 21.55

20.86 ± 18.85

0.61

0.542

AST (U/L)

23.94 ± 19.80

24.78 ± 19.95

 − 0.36

0.719

TBIL (μmol/L)

10.58 ± 4.89

11.71 ± 6.09

 − 1.84

0.067

IBIL (μmol/L)

6.13 ± 3.14

6.69 ± 3.57

 − 1.45

0.148

DBIL (μmol/L)

4.45 ± 2.54

5.02 ± 3.22

 − 1.77

0.077

RBG (mmol/L)

6.67 ± 2.48

7.22 ± 2.67

 − 1.80

0.072

  1. *Data presented as Median (Q1, Q3)
  2. AECOPD Acute exacerbation chronic obstructive pulmonary disease, WBC White blood cells, NS Neutrophils, LYM Lymphocytes, EOS Eosinophils, NLR Neutrophil–lymphocyte ratio, RBC Red blood cell, HB Hemoglobin, HCT Hematocrit, PLT Platelet, PCT Procalcitonin, CRP C-reactive protein, ESR Erythrocyte sedimentation rate, ABG Arterial blood gas, AB Actual standard bicarbonate, SB Standard bicarbonate, AG Anion gap, Na+ Sodium ions, K+ Potassium ions, Ca2+ Calcium ions, Mg2+ Magnesium ions, ALB Albumin, BUN Blood urea nitrogen, Cr Creatinine, ALT Alanine aminotransferase, AST Aspartate aminotransferase, TBIL Total bilirubin, IBIL Indirect bilirubin, DBIL Direct bilirubin, RBG Random blood glucose