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Fig. 5 | BMC Pulmonary Medicine

Fig. 5

From: LncRNA AK089514/miR-125b-5p/TRAF6 axis mediates macrophage polarization in allergic asthma

Fig. 5

TRAF6 is a direct target gene of miR-125b-5p. A Venn diagram showing 22 putative miR-125b-5p target genes predicted by two databases (ENCORI and miRWalk). B Putative binding sequence between miR-125b-5p and the 3′-UTR region of TRAF6. C Dual luciferase reporter assay indicted that miR-125b-5p could bind to the 3′-UTR region of TRAF6. D Expression levels of TRAF6 were determined by western blot in miR-125b-5p-overexpressed or miR-125b-5p-silenced BMDMs cells. Data are mean ± SD from three independent experiments. ***P < 0.001

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