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Table 3 Baseline characteristics and comorbidities based on age in patients with idiopathic pulmonary fibrosis

From: Epidemiology and comorbidities in idiopathic pulmonary fibrosis: a nationwide cohort study

 

Total (n = 21,111)

Older age (≥ 70 years) (n = 12,762)

Younger age (< 70 years) (n = 8349)

p value

Respiratory diseases

COPD

7882 (37.34%)

5027 (39.39%)

2855 (34.20%)

 < 0.001

Lung cancer

706 (3.34%)

430 (3.37%)

276 (3.31%)

0.802

Pulmonary embolism

338 (1.60%)

245 (1.92%)

93 (1.11%)

 < 0.001

Pulmonary hypertension

315 (1.49%)

175 (1.37%)

140 (1.68%)

0.073

Obstructive sleep apnoea

65 (0.31%)

34 (0.27%)

31 (0.37%)

0.179

Non-respiratory diseases

GERD

14,953 (70.83%)

9065 (71.03%)

5888 (70.52%)

0.427

Dyslipidaemia

13,286 (62.93%)

8289 (64.95%)

4997 (59.85%)

 < 0.001

Hypertension

12,464 (59.04%)

8595 (67.35%)

3869 (46.34%)

 < 0.001

Diabetes mellitus

9483 (44.92%)

6245 (48.93%)

3238 (38.78%)

 < 0.001

Ischaemic heart disease

5431 (25.73%)

3825 (29.97%)

1606 (19.24%)

 < 0.001

Anxiety

4238 (20.07%)

2915 (22.84%)

1323 (15.85%)

 < 0.001

Depression

3142 (14.88%)

2222 (17.41%)

920 (11.02%)

 < 0.001

Congestive heart failure

2887 (13.68%)

2152 (16.86%)

735 (8.80%)

 < 0.001

CCI

 < 0.001

0

577 (2.73%)

230 (1.80%)

347 (4.16%)

 

1

3109 (14.73%)

1532 (12.00%)

1577 (18.89%)

 

2

4109 (19.46%)

2250 (17.63%)

1859 (22.27%)

 

3

3823 (18.11%)

2287 (17.92%)

1536 (18.40%)

 

 ≥ 4

9493 (44.97%)

6463 (50.64%)

3030 (36.29%)

 

CCI, mean (standard deviation)

3.67 (2.40)

3.99 (2.48)

3.20 (2.20)

 < 0.001

  1. All values are presented as number (%)
  2. CCI Charlson comorbidity index, COPD chronic obstructive pulmonary disease, GERD gastro-oesophageal reflux disease
  3. P values calculated by chi-square tests or Wilcoxon rank sums test