From: Epidemiology and comorbidities in idiopathic pulmonary fibrosis: a nationwide cohort study
 | Total (n = 21,111) | Older age (≥ 70 years) (n = 12,762) | Younger age (< 70 years) (n = 8349) | p value |
---|---|---|---|---|
Respiratory diseases | ||||
COPD | 7882 (37.34%) | 5027 (39.39%) | 2855 (34.20%) |  < 0.001 |
Lung cancer | 706 (3.34%) | 430 (3.37%) | 276 (3.31%) | 0.802 |
Pulmonary embolism | 338 (1.60%) | 245 (1.92%) | 93 (1.11%) |  < 0.001 |
Pulmonary hypertension | 315 (1.49%) | 175 (1.37%) | 140 (1.68%) | 0.073 |
Obstructive sleep apnoea | 65 (0.31%) | 34 (0.27%) | 31 (0.37%) | 0.179 |
Non-respiratory diseases | ||||
GERD | 14,953 (70.83%) | 9065 (71.03%) | 5888 (70.52%) | 0.427 |
Dyslipidaemia | 13,286 (62.93%) | 8289 (64.95%) | 4997 (59.85%) |  < 0.001 |
Hypertension | 12,464 (59.04%) | 8595 (67.35%) | 3869 (46.34%) |  < 0.001 |
Diabetes mellitus | 9483 (44.92%) | 6245 (48.93%) | 3238 (38.78%) |  < 0.001 |
Ischaemic heart disease | 5431 (25.73%) | 3825 (29.97%) | 1606 (19.24%) |  < 0.001 |
Anxiety | 4238 (20.07%) | 2915 (22.84%) | 1323 (15.85%) |  < 0.001 |
Depression | 3142 (14.88%) | 2222 (17.41%) | 920 (11.02%) |  < 0.001 |
Congestive heart failure | 2887 (13.68%) | 2152 (16.86%) | 735 (8.80%) |  < 0.001 |
CCI |  < 0.001 | |||
0 | 577 (2.73%) | 230 (1.80%) | 347 (4.16%) | Â |
1 | 3109 (14.73%) | 1532 (12.00%) | 1577 (18.89%) | Â |
2 | 4109 (19.46%) | 2250 (17.63%) | 1859 (22.27%) | Â |
3 | 3823 (18.11%) | 2287 (17.92%) | 1536 (18.40%) | Â |
 ≥ 4 | 9493 (44.97%) | 6463 (50.64%) | 3030 (36.29%) |  |
CCI, mean (standard deviation) | 3.67 (2.40) | 3.99 (2.48) | 3.20 (2.20) |  < 0.001 |