Table 1 Main characteristics of studies included
Study | Country | Study population (%) | Mean age | Study design | Criteria | Sample size (n) | Antifungal intervention (n) | Proven/probable IPA (n (%)) |
|---|---|---|---|---|---|---|---|---|
Subhagan [20] | India | HM (0) | Unknown | Retrospective cohort | 2020a | 30 | 0 | 10 (33) |
Mikulska [21] | Italy | HM (< 50) | 64 (30–82) | Retrospective cohort | 2020 | 111 | Unknown | 31 (28) |
Scharmann [22] | German | HM (> 50) | 61 (18–92) | Retrospective cohort | 2020 | 93 | 44 | 10 (11) |
Unterman [23] | Israel | HM (0) | 53.5 ± 16.3 | Retrospective cohort | 2008b | 95 | 59 | 5 (5) |
Pelzer [24] | German | HM (100) | Unknown | Prospective cohort | 2008 | 100 | 100 | 23 (23) |
Mikulska [25] | Italy | HM (> 50) | 54 (20–81) | Retrospective cohort | 2008 | 123 | 36 | 30 (24) |
Hardak [26] | Israel | HM (> 50) | 55 | Retrospective cohort | 2008 | 1248 | 31 | 287 (23) |
Wehrle-Wieland [27] | Switzerland | HM (100) | 57 (21–87) | Prospective cohort | 2008 | 167 | 53 | 33 (20) |
Prattes [28] | Austria | HM (< 50) | 65 | Retrospective case–control | Similard | 35 | Unknown | 18 (51) |
Heldta [29] | Austria | HM (100) | 55 | Prospective cohort | 2008 | 101 | 85 | 11 (11) |
Guegan [30] | France | HM (> 50) | 62 | Prospective cohort | 2008 | 387 | Unknown | 38 (10) |
Grancini [31] | Italy | HM (< 50) | 51.3 (7–83) | Retrospective case–control | 2008 | 110 | Unknown | 21 (19) |
Denis [32] | France | HM (> 50) | Unknown | Retrospective cohort | 2008 | 73 | 29 | 31 (42) |
Boch [33] | German | HM (< 50) | Unknown | Prospective cohort | 2008 | 44 | Unknown | 9 (20) |
Montesinos [34] | Belgian | HM (< 50) | Unknown | Retrospective cohort | 2008 | 100 | Unknown | 29 (29) |
Eigl [35] | Austria | HM (100) | 58 | Prospective cohort | 2008 | 72 | 46 | 16 (22) |
Bhimji [36] | Canada | HM (0) | Unknown | Prospective cohort | Similar | 201 | Unknown | 23 (11) |
Zhang [37] | China | HM (0) | Unknown | Retrospective cohort | 2008 | 90 | Unknown | 10 (19) |
Chong [38] | Dutch and Belgian | HM (100) | 56.6 (17.5–82.6) | Retrospective cohort | 2008 | 201 | Unknown | 52 (26) |
Boch [39] | German | HM (> 50) | Unknown | Prospective cohort | 2008 | 99 | 51 | 43 (43) |
Chong [40] | Nehterlands | HM (< 50) | Unknown | Retrospective cohort | 2008 | 77 | 0 | 22 (29) |
Hoenigl [41] | Austria and German | HM (> 50) | 58 (24–77) | Prospective cohort | 2008 | 67 | Unknown | 10 (15) |
Heng [42] | Australia | HM (100) | Unknown | Retrospective cohort | 2008 | 116 | 79 | 18 (16) |
Reinwald [43] | German | HM (100) | Unknown | Prospective cohort | 2008 | 76 | 65 | 29 (38) |
Reinwald [44] | German | HM (100) | 56 | Retrospective cohort | 2008 | 226 | 146 | 48 (21) |
Buess [45] | Switzerland | HM (> 50) | 50.5 | Prospective cohort | 2008 | 191 | 111 | 11 (6) |
Torelli [46] | Italy | HM (< 50) | Unknown | Prospective cohort | 2008 | 158 | Unknown | 17 (11) |
Luong [47] | America | HM (0) | 58.4 | Retrospective cohort | Similar | 150 | 75 | 16 (11) |
Hadrich [48] | Tunisia | HM (100) | Unknown | Prospective case–control | 2008 | 163 | Unknown | 44 (27) |
Fréalle [49] | France | HM (100) | 49 | Retrospective cohort | 2002c | 57 |  > 50% | 25 (44) |
Shahid [50] | India | HM (0) | Unknown | Prospective case–control | 2002 | 69 | 0 | 23 (33) |
Khot [51] | America | HM (100) | 53.68 | Retrospective cohort | 2002 | 81 | Unknown | 13 (16) |
Musher [52] | America | HM (100) | Unknown | Retrospective case–control | 2002 | 93 | 34 | 46 (49) |
Sanguinetti [53] | Italy | HM (100) | Unknown | Retrospective cohort | 2002 | 44 | Unknown | 20 (45) |
Rantakokko [54] | Finland | HM (100) | Unknown | Retrospective cohort | 2002 | 66 | Unknown | 11 (174) |
Raad [55] | America | HM (< 50) | 50 | Prospective cohort | Similar | 249 | Unknown | 32 (13) |
Hayette [56] | Belgium | HM (< 50) | Unknown | Retrospective cohort | Similar | 74 | Unknown | 10 (14) |
Buchheidt [57] | German | HM (> 50) | Unknown | Prospective cohort | Similar | 176 | Unknown | 31 (19) |
Jones [58] | British | HM (100) | Unknown | Retrospective cohort | Similar | 69 | Unknown | 12 (17) |
Bretagne [59] | France | HM (> 50) | Unknown | Prospective cohort | Similar | 52 | Unknown | 3 (6) |
Tang [60] | British | HM (> 50) | Unknown | Retrospective case–control | Similar | 51 | Unknown | 4 (8) |