From: Predictors of pulmonary hypertension in patients with hypersensitivity pneumonitis
Factors | HP without PH (n = 43) | HP with PH (n = 17) | P | ||
---|---|---|---|---|---|
Mean | SD | Mean | SD | ||
Age | 42.6 | 13.9 | 39.3 | 12 | 0.36$ |
Sex | N | % | N | % | |
Male | 6 | 13.95 | 1 | 5.88 | 0.38# |
Female | 37 | 86.05 | 16 | 94.12 | |
Bird exposure | N | % | N | % | |
Yes | 38 | 88.37 | 12 | 70.59 | 0.11# |
Median | IQR | Median | IQR | ||
Dyspnea score (MMRC) | 2 | (2–2) | 3 | (2–3) | 0.003§ |
Duration (years) | 2 | (1–3) | 3 | (2–4) | 0.27§ |
Clinical features | N | % | N | % | |
Syncope | 2 | 4.65 | 7 | 41.18 | 0.001# |
Palpitation | 12 | 27.91 | 12 | 70.59 | 0.002# |
Easy fatigability | 21 | 48.84 | 14 | 82.35 | 0.01# |
Clubbing | 12 | 27.91 | 9 | 52.94 | 0.06# |
Crepitation on auscultation | 27 | 62.79 | 14 | 82.35 | 0.12# |
HRCT pattern | N | % | N | % | |
Typical non-fibrotic HP | 41 | 95.35 | 5 | 29.41 | < 0.001# |
Typical fibrotic HP | 2 | 4.65 | 12 | 70.59 | |
O2 saturation % | N | % | N | % | |
Less than 90% | 3 | 6.98 | 14 | 82.35 | < 0.001# |
More than 90% | 40 | 93.02 | 3 | 17.65 | |
FVC% | 60% | 17% | 53% | 16% | 0.18$ |
FVC restriction degree* | 1 | (1–2) | 2 | (1–2) | 0.54§ |
FEV1% | 0.59 | 0.17 | 0.60 | 0.16 | 0.96$ |
SO2 in RA | 0.93 | 0.08 | 0.81 | 0.12 | 0.001$ |
Min SO2 in 6MWT | 0.87 | 0.09 | 0.71 | 0.13 | 0.001$ |
Desaturation index | 0.04 | (0.03–0.1) | 0.11 | (0.07–0.19) | 0.001§ |
6MWD | 271.90 | 63.20 | 231.10 | 74.70 | 0.08$ |
PO2 | 75.30 | 11.70 | 52.80 | 10.40 | < 0.001$ |
PCO2 | 41.63 | 4.54 | 37.06 | 6.86 | 0.01$ |
FIO2 | 0.22 | 0.03 | 0.28 | 0.05 | < 0.001$ |
Aa PO2 gradient | 23.73 | (15.1–31.9) | 106.24 | (91.6–119.2) | < 0.001§ |