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Table 3 Demographic data, clinical, radiological and functional characteristics of HP patients with and without PH

From: Predictors of pulmonary hypertension in patients with hypersensitivity pneumonitis

Factors

HP without PH (n = 43)

HP with PH (n = 17)

P

Mean

SD

Mean

SD

Age

42.6

13.9

39.3

12

0.36$

Sex

N

%

N

%

 

Male

6

13.95

1

5.88

0.38#

Female

37

86.05

16

94.12

 

Bird exposure

N

%

N

%

 

Yes

38

88.37

12

70.59

0.11#

 

Median

IQR

Median

IQR

 

Dyspnea score (MMRC)

2

(2–2)

3

(2–3)

0.003§

Duration (years)

2

(1–3)

3

(2–4)

0.27§

Clinical features

N

%

N

%

 

Syncope

2

4.65

7

41.18

0.001#

Palpitation

12

27.91

12

70.59

0.002#

Easy fatigability

21

48.84

14

82.35

0.01#

Clubbing

12

27.91

9

52.94

0.06#

Crepitation on auscultation

27

62.79

14

82.35

0.12#

HRCT pattern

N

%

N

%

 

Typical non-fibrotic HP

41

95.35

5

29.41

 < 0.001#

Typical fibrotic HP

2

4.65

12

70.59

 

O2 saturation %

N

%

N

%

 

Less than 90%

3

6.98

14

82.35

 < 0.001#

More than 90%

40

93.02

3

17.65

 

FVC%

60%

17%

53%

16%

0.18$

FVC restriction degree*

1

(1–2)

2

(1–2)

0.54§

FEV1%

0.59

0.17

0.60

0.16

0.96$

SO2 in RA

0.93

0.08

0.81

0.12

0.001$

Min SO2 in 6MWT

0.87

0.09

0.71

0.13

0.001$

Desaturation index

0.04

(0.03–0.1)

0.11

(0.07–0.19)

0.001§

6MWD

271.90

63.20

231.10

74.70

0.08$

PO2

75.30

11.70

52.80

10.40

 < 0.001$

PCO2

41.63

4.54

37.06

6.86

0.01$

FIO2

0.22

0.03

0.28

0.05

 < 0.001$

Aa PO2 gradient

23.73

(15.1–31.9)

106.24

(91.6–119.2)

 < 0.001§

  1. Bold value indicates FVC %
  2. *FVC restriction degree 1 = normal and mild restriction, 2 = moderate and sever restriction
  3. P < 0.05 considered significant
  4. $Independent t-test
  5. §Kruskal Wallis test
  6. #Chi square test