Characteristics | TCGA (training set, N = 509) | GSE68465 (validation set, N = 443) | Total (N = 952) | p value | FDR |
---|---|---|---|---|---|
Time | |||||
Mean ± SD | 909.60 ± 892.04 | 1578.13 ± 1087.35 | 1220.31 ± 1041.95 | ||
Median[min–max] | 658.00 [4.00,7248.00] | 1410.00 [0.90,6120.00] | 900.00 [0.90,7248.00] | ||
State | 1.10*10–7 | 4.50*10–7 | |||
Alive | 326 (34.24%) | 207 (21.74%) | 533 (55.99%) | ||
Dead | 183 (19.22%) | 236 (24.79%) | 419 (44.01%) | ||
Age | |||||
Mean ± SD | 65.29 ± 10.03 | 64.42 ± 10.10 | 64.88 ± 10.07 | ||
Median[min–max] | 66.00 [33.00,88.00] | 65.00 [33.00,87.00] | 65.50 [33.00,88.00] | ||
Sex | 0.22 | 0.33 | |||
Female | 274 (28.78%) | 220 (23.11%) | 494 (51.89%) | ||
Male | 235 (24.68%) | 223 (23.42%) | 458 (48.11%) | ||
T | 0.17 | 0.33 | |||
T1 | 171 (17.96%) | 150 (15.76%) | 321 (33.72%) | ||
T2 | 272 (28.57%) | 251 (26.37%) | 523 (54.94%) | ||
T3 | 45 (4.73%) | 28 (2.94%) | 73 (7.67%) | ||
T4 | 18 (1.89%) | 12 (1.26%) | 30 (3.15%) | ||
TX | 3 (0.32%) | 0 (0.0e + 0%) | 3 (0.32%) | ||
NA | 0 (0.0e + 0%) | 2 (0.21%) | 2 (0.21%) | ||
N | 0.06 | 0.18 | |||
N0 | 329 (34.56%) | 299 (31.41%) | 628 (65.97%) | ||
N1 | 97 (10.19%) | 88 (9.24%) | 185 (19.43%) | ||
N2 | 70 (7.35%) | 53 (5.57%) | 123 (12.92%) | ||
N3 | 2 (0.21%) | 0 (0.0e + 0%) | 2 (0.21%) | ||
NA | 0 (0.0e + 0%) | 2 (0.21%) | 2 (0.21%) | ||
NX | 10 (1.05%) | 1 (0.11%) | 11 (1.16%) | ||
NA | 1 (0.11%) | 0 (0.0e + 0%) | 1 (0.11%) | ||
M | 4.20*10–200 | 2.50*10–199 | |||
M0 | 341 (35.82%) | 0 (0.0e + 0%) | 341 (35.82%) | ||
M1 | 17 (1.79%) | 0 (0.0e + 0%) | 17 (1.79%) | ||
M1a | 2 (0.21%) | 0 (0.0e + 0%) | 2 (0.21%) | ||
M1b | 5 (0.53%) | 0 (0.0e + 0%) | 5 (0.53%) | ||
MX | 140 (14.71%) | 0 (0.0e + 0%) | 140 (14.71%) | ||
NA | 4 (0.42%) | 443 (46.53%) | 447 (46.95%) | ||
Stage | 6.30*10–198 | 3.10*10–197 | |||
Stage I | 273 (28.68%) | 0 (0.0e + 0%) | 273 (28.68%) | ||
Stage II | 122 (12.82%) | 0 (0.0e + 0%) | 122 (12.82%) | ||
Stage III | 81 (8.51%) | 0 (0.0e + 0%) | 81 (8.51%) | ||
Stage IV | 25 (2.63%) | 0 (0.0e + 0%) | 25 (2.63%) | ||
NA | 8 (0.84%) | 443 (46.53%) | 451 (47.37%) |