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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: The balance between lung regulatory T cells and Th17 cells is a risk indicator for the acute exacerbation of interstitial lung disease after surgery: a case-control study

Fig. 1

Typical immunohistochemical findings of Th17 and Treg in patients with and without AE. A dual-labeled cell was defined by the presence of cytoplasmic staining for CD4 (red chromogen), STAT3, and FOXP3 (brown chromogen) and nuclear staining for the interrogated transcription factor (blue chromogen). The yellow arrow shows an example of a double-stained cell. CD4 was more extensively stained in patients without AE. CD4+/STAT3+ were more prominent in the AE group (A) than in the non-AE group (B). CD4+/FOXP3 appeared less stained in the AE group (C) than in the non-AE group (D)

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