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Table 2 The prognostic factors associated with the risk of ARDS for patients with sepsis

From: A prediction model for predicting the risk of acute respiratory distress syndrome in sepsis patients: a retrospective cohort study

Variables

Univariate logistic regression model

Multivariate logistic regression model

RR (95% CI)

P

RR (95% CI)

P

Age

0.988 (0.985–0.990)

 < 0.001

–

–

Gender

    

 Female

Ref

 

–

–

 Male

0.984 (0.898–1.079)

0.734

–

–

BMI

    

 < 18.5

Ref

 

Ref

 

 ≥ 18.5 and < 25

0.673 (0.516–0.878)

0.003

0.732 (0.542–0.987)

0.041

 ≥ 25 and < 30

0.723 (0.556–0.941)

0.016

0.748 (0.555–1.008)

0.057

 ≥ 30

1.050 (0.810–1.362)

0.712

0.863 (0.642–1.159)

0.326

Ethnicity

    

 White

Ref

 

–

–

 Black

1.346 (1.145–1.583)

 < 0.001

–

–

 Other/unknown

1.298 (1.171–1.438)

 < 0.001

–

–

Marital status

    

 Single

Ref

 

–

–

 Married

0.728 (0.653–0.812)

 < 0.001

–

–

 Other/unknown

0.851 (0.755–0.959)

0.008

–

–

SBP

0.988 (0.927–1.053)

0.715

–

–

DBP

0.990 (0.933–1.051)

0.748

–

–

Respiratory rate

1.075 (1.067–1.082)

 < 0.001

1.049 (1.041–1.058)

 < 0.001

Urine output

1.635 (1.563–1.710)

 < 0.001

1.000 (1.000–1.000)

 < 0.001

PCO2

1.019 (1.015–1.022)

 < 0.001

1.017 (1.013–1.021)

 < 0.001

FiO2

0.998 (0.996–1.000)

0.016

–

–

HCO3 −

0.975 (0.966–0.985)

 < 0.001

–

–

Hemoglobin

0.931 (0.913–0.950)

 < 0.001

–

–

PLT

1.017 (0.973–1.063)

0.459

–

–

WBC

1.015 (1.010–1.019)

 < 0.001

–

–

Creatinine

1.076 (1.048–1.104)

 < 0.001

–

–

BUN

1.008 (1.006–1.010)

 < 0.001

1.005 (1.002–1.007)

 < 0.001

Glucose

1.002 (1.001–1.002)

 < 0.001

–

–

Vasopressin

    

 No

Ref

 

Ref

 

 Yes

4.144 (3.705–4.635)

 < 0.001

1.711 (1.491–1.964)

 < 0.001

CRRT

    

 No

Ref

 

Ref

 

 Yes

5.319 (4.619–6.126)

 < 0.001

4.870 (4.054–5.851)

 < 0.001

Ventilation status

    

 High flow

Ref

 

Ref

 

 Invasive vent

11.951 (6.866–20.801)

 < 0.001

5.617 (3.122–10.107)

 < 0.001

 Non-invasive vent

14.495 (9.616–21.850)

 < 0.001

7.387 (4.825–11.308)

 < 0.001

 Oxygen

4.186 (2.002–8.752)

 < 0.001

1.681 (0.751–3.760)

0.206

 Trach

4.382 (2.923–6.570)

 < 0.001

2.906 (1.914–4.412)

 < 0.001

PLT-transfusion

    

 No

Ref

 

–

–

 Yes

1.748 (1.558–1.962)

 < 0.001

–

–

Diabetes

    

 No

Ref

 

–

–

 Yes

1.037 (0.942–1.142)

0.460

–

–

Chronic pulmonary disease

    

 No

Ref

 

Ref

 

 Yes

1.455 (1.321–1.604)

 < 0.001

1.353 (1.208–1.514)

 < 0.001

Renal disease

    

 No

Ref

 

–

–

 Yes

1.089 (0.978–1.214)

0.121

–

–

Malignant cancer

    

 No

Ref

 

Ref

 

 Yes

1.252 (1.097–1.428)

 < 0.001

1.278 (1.097–1.488)

0.002

Liver disease

    

 No

Ref

 

Ref

 

 Yes

2.125 (1.899–2.377)

 < 0.001

1.720 (1.505–1.967)

 < 0.001

Leukemia

    

 No

Ref

 

–

–

 Yes

1.386 (1.000–1.922)

0.050

–

–

Myocardial infarct

    

 No

Ref

 

–

–

 Yes

0.967 (0.863–1.083)

0.557

–

–

Septic shock

    

 No

Ref

 

Ref

 

 Yes

2.380 (2.015–2.811)

 < 0.001

1.268 (1.044–1.541)

0.017

Pancreatitis

    

 No

Ref

 

Ref

 

 Yes

3.713 (2.892–4.766)

 < 0.001

2.273 (1.693–3.053)

 < 0.001

  1. BMI Body mass index; SBP Systolic blood pressure; DBP Diastolic blood pressure; SPO2 Pulse oxygen saturation; PCO2 Partial pressure of carbon dioxide; PO2 Oxygen partial pressure; FiO2 Fraction of inspired oxygen; HCO3− Bicarbonate; PLT Platelet; WBC White blood cell; BUN Blood urea nitrogen; CRRT Continuous renal replacement therapy; RBC Red blood cell; PLT Platelets; ARDS Acute respiratory distress syndrome; RR Relative risk; CI confidence interval
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BMC Pulmonary Medicine

ISSN: 1471-2466

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