Diagnostic accuracy of a set of clinical and radiological criteria for screening of COVID-19 using RT-PCR as the reference standard

Table 4 Cross tabulation of the results of the proposed set of clinical-radiological criteria versus the RT-PCR, considering the subgroup of patients with severe respiratory disfunction at ICU admission

Subgroup of patients with severe respiratory disfunction		RT-PCR (reference standard)
Subgroup of patients with severe respiratory disfunction		Positive	Negative	Total
Classification by the clinical-radiological criteria	Strong Suspicion	246 (52.6%)	72 (15.4%)	318 (67.9%)	PPV^a 77.4% (72.8–82%)
Classification by the clinical-radiological criteria	Weak Suspicion	3 (0.6%)	147 (31.4%)	150 (32.1%)	NPV^a 98% (95.8–99.9%)
	Total	249 (53.2%)	219 (46.8%)	468 (100%)
		Sensitivity^a 98.8% (97.4–99.9%)	Specificity^a 67.1% (60.9–73.3%)		Accuracy^a 84.0% (80.7–87.3%)

RT-PCR Reverse transcription polymerase chain reaction, PPV positive predictive value, NPV negative predictive value
^aValues presented with their respective 95% confidence intervals
Likelihood of a positive test: 3.01; likelihood of a negative test: 0.02

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