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Table 2 Crude HRs for the presence of new-onset dementia among patients with COPD and controls

From: The adjusted impact of different severities of acute exacerbations and medications on the risk of developing dementia in COPD patients

Development of dementia during the 5-year follow-up period

Total sample

(n = 102,636)

COPD group (n = 51,318)

Control group (n = 51,318)

 

No.

%

No.

%

No.

%

Yes

1,488

1.4

1,025

2.0

423

0.8

No

101,188

98.6

50,293

98.0

50,895

99.2

Crude HR (95% CI)

-

2.51a (2.24–2.81)

-

Adjusted HR (95% CI)

-

2.42b (2.16–2.71)

-

  1. a The crude HR was calculated using a Cox proportional hazards model stratified by age, sex and the year of index hospitalization
  2. bHR adjusted for demographics and baseline comorbidities (i.e., diabetes, hypertension, renal failure, liver cirrhosis, stroke and osteoporosis)