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Table 2 Invasive cardiopulmonary exercise testing

From: Primary mitochondrial disease as a rare cause of unclear breathlessness and distinctive performance degradation – a case report

parameter

unit

baseline

45° upright position

unloaded cycling

exercise 25 W

heart rate

min− 1

80.0

81.0

120.0

157.0

systolic blood pressure

mmHg

115.0

126.0

134.0

135.0

diastolic blood pressure

mmHg

72.0

79.0

89.0

77.0

mean systemic arterial pressure

mmHg

99.0

90.0

113.0

99.0

PAWP

mmHg

7.0

9.0

9.0

15.0

CVP

mmHg

7.0

6.0

7.0

13.0

VO2 -table

l/min

193.7

   

VO2 -measured

l/min

223.0

162.0

353.0

530.0

CO (iFM)

l/min

5.8

   

CO (dFM)

l/min

6.7

4.5

11.6

14.9

SVR (iFM)

WU

15.9

   

PVR (iFM)

WU

1.4

   

CI (iFM)

l/min/m²

3.3

   

SVR (dFM)

WU

13.8

18.5

9.1

5.8

PVR (dFM)

WU

1.2

1.3

0.7

0.6

CI (dFM)

l/min/m²

3.8

2.6

6.6

8.5

CO (TD, mean)

l/min

6.3

5.3

10.1

10.8

SVR (TD, mean)

WU

14.7

15.9

10.5

8.0

PVR (TD, mean)

WU

1.3

1.1

0.8

0.8

CI (TD, mean)

l/min/m2

3.6

3.0

5.7

6.1

PAPsys

mmHg

20.0

18.0

30.0

35.0

PAPdia

mmHg

8.0

8.0

8.0

14.0

PAPmean

mmHg

15.0

15.0

17.0

24.0

paO2

mmHg

98.8

103.0

106.0

126.0

paCO2

mmHg

29.9

29.6

28.4

21.2

SaO2

%

97.5

97.6

98.2

98.0

SvO2

%

79.5

78.4

81.8

78.9

taO2

Vol%

18.1

18.1

18.2

18.2

tvO2

Vol%

14.8

14.6

15.2

14.6

a-vDO2

Vol%

3.3

3.6

3.0

3.5

lactate, arterial

mmol/l

3.3

2.6

5.4

15.0

  1. Abbbreviations: a-vDO2 arterial-venous volume difference for oxygen, CI cardiac index, CO cardiac output, CVP central venous pressure, dFM direct method of Fick, iFM indirect method of Fick, paCO2 arterial partial pressure of carbon dioxide, paO2 arterial partial pressure of oxygen, PAPdia diastolic pulmonary artery pressure, PAPmean mean pulmonary artery pressure, PAPsys systolic pulmonary artery pressure, PAWP pulmonary arterial wedge pressure, PVR pulmonary vascular resistance, SaO2 arterial oxygen saturation, SvO2 venous oxygen saturation, SVR systemic vascular resistance, taO2 arterial oxygen tension in percent, tvO2 venous oxygen tension in percent, TD thermodilution, VO2 oxygen uptake per minute, WU wood unit
  2. Cardiac output, cardiac index and resistances were calculated by thermodilution (TD) and direct and indirect method of Fick (dFM resp. iFM), with the iFM method using the table of LaFarge.