Pulmonary benign metastasizing leiomyoma in patients aged 45 years and younger: clinical features and novelty in treatment

Table 2 Follow-up and outcomes of conventional treatment for PBML patients (N = 40) from literature and our hospital

Treatment options	No. of patients	Follow-up time (month)	Outcomes (N, %)
Treatment options	No. of patients	Follow-up time (month)	Radiologically progressive	Radiologically stable	Radiologically regressive
Observation	7	Median 18.0 IQRs 12.0–38.0	0 (0%)	7 (100.0%)	0 (0%)
GnRHa	10	Median 12.0 IQRs 8.5–20.3	1 (10.0%)	5 (50.0%)	4 (40.0%)
Surgical castration^*	14	Median 19.5 IQRs 11.3–29.5	2 (14.3%)	9 (64.3%)	3 (21.4%)
Anti-estrogen drugs^†	6	Median 15.5 IQRs 3.5–33.5	3 (50.0%)	3 (50.0%)	0 (0%)
Surgery^††	3	Median 18.0 IQRs 15.0-20.6	2 (66.7%)	0 (0%)	1 (33.3%)

^*including 4 patients simultaneously treated with surgical resection of pulmonary metastatic lesions, and all of them achieved no recurrence; ^†including 1 patient simultaneously treated with surgical resection of pulmonary metastatic lesions, and she achieved no recurrence; ^††patients only received surgical resection of pulmonary metastatic lesions

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