Skip to main content

Table 3 Serological data at the time of admission

From: Impact of respiratory bacterial infections on mortality in Japanese patients with COVID-19: a retrospective cohort study

 

No Bacterial Infection (n = 1635)

Respiratory Co-infection (n = 54)

Respiratory Secondary Infection (n = 85)

P value

WBC (/μL)

5627.5 ± 2693.5

7579.8 ± 3868.5

7927.3 ± 4971.6

 < 0.0001a=**/b=**

Neutrophil (/ μL)

3633.8 ± 2440.9

6109.9 ± 4275.7

6689.5 ± 4737.9

 < 0.0001a=**/b=**

Lymphocyte(/μL)

1059.8 ± 616.3

705.2 ± 438.1

742.0 ± 462.9

 < 0.0001a=**/b=**

Hb (g/dL)

14.1 ± 1.88

13.5 ± 1.98

13.1 ± 2.15

 < 0.0001a=*/b=**

PLT (× 103 /μL)

19.9 ± 7.65

20.4 ± 7.50

19.5 ± 8.95

0.80

Alb (g/dL)

3.78 ± 0.61

3.29 ± 0.92

3.12 ± 0.62

 < 0.0001a=**/b=**

TB (mg/dL)

0.66 ± 0.36

0.78 ± 0.65

0.69 ± 0.43

0.08

ALP (IU/L)

175.5 ± 124.0

220.3 ± 142.3

197.3 ± 100.6

0.02a=*

AST (IU/L)

40.9 ± 69.1

54.7 ± 53.1

53.0 ± 91.3

0.13

ALT (IU/L)

38.6 ± 91.2

50.7 ± 63.5

43.8 ± 54.4

0.56

BUN (mg/dL)

16.5 ± 10.6

27.6 ± 25.5

31.4 ± 41.2

 < 0.0001a=**/b=**

Cr (mg/dL)

1.06 ± 1.43

1.68 ± 2.34

1.38 ± 1.47

0.0018 a=**

LDH (IU/L)

268.7 ± 136.6

337.1 ± 150.4

368.2 ± 184.1

 < 0.0001a=**/b=**

UA (mg/dL)

4.88 ± 1.81

5.55 ± 2.34

5.11 ± 2.21

0.04a=*

CK (IU/L)

149.7 ± 456.3

248.7 ± 347.8

218.9 ± 387.1

0.14

Na (mEq/L)

138.3 ± 3.62

137.7 ± 5.53

137.4 ± 3.91

0.08

K (mEq/L)

3.98 ± 0.46

4.03 ± 0.54

4.20 ± 0.55

0.0002b=**

Cl (mEq/L)

101.8 ± 3.97

100.7 ± 5.56

102.1 ± 3.80

0.11

BNP (pg/mL)

69.4 ± 401.9

157.1 ± 403.0

104.2 ± 169.6

0.51

IgG(mg/dL)

1151.2 ± 359.4

1128.4 ± 293.3

1197.8 ± 293.6

0.27

Ferritin (ng/mL)

531.1 ± 583.0

814.4 ± 712.5

876.7 ± 982.0

 < 0.0001a=*/b=**

KL-6 (IU/L)

315.9 ± 302.4

422.0 ± 308.9

488.2 ± 439.1

 < 0.0001 b=**

HbA1c (%)

6.37 ± 1.31

6.76 ± 1.60

6.88 ± 1.39

0.002 b=**

CRP (mg/dL)

4.48 ± 5.35

10.8 ± 9.61

9.93 ± 10.1

 < 0.0001a=**/b=**

Procalcitonin (ng/mL)

0.16 ± 0.62

2.81 ± 9.57

1.05 ± 2.83

 < 0.0001a=**/b=*

  1. Data are shown as mean ± SD
  2. WBC white blood cell, Hb hemoglobin, PLT platelet, Alb albumin, TB total bilirubin, ALP alkaline phosphatase, AST aspartate aminotransferase, ALT alanine aminotransferase, BUN blood urea nitrogen, Cr creatinine, LDH lactate dehydrogenase, UA uric acid, CK creatinine kinase, Na sodium, K potassium, Cl chlorine, BNP brain natriuretic peptide, IgG Immunoglobulin G, KL-6 Krebs von den Lungen-6, CRP C-reactive protein
  3.  *p < 0.05
  4.  **p < 0.01
  5.  aComparison of patients without infection versus patients with community-acquired co-infection
  6.   bComparison of patients without infection versus patients with hospital-acquired secondary infection