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Table 2 Change in primary and secondary outcome measures in post-treatment phase relative to baseline

From: Cough desensitization treatment for patients with refractory chronic cough: results of a second pilot randomized control trial

 

Mean Change at PT1

 

Mean Change at PT2

 
 

CDT

Sham

 

CDT

Sham

  
 

Mean

95% CI

Mean

95% CI

 

mean

95% CI

Mean

95% CI

N2p

F-Value

P = Value

LCQ Total

5.32

3.04 to 7.60

2.34

− 0.33 to 5.02

 

6.35

4.07 to 8.63

2.17

− 0.50 to 4.85

0.14

2.657

0.058

LCQ Phys

1.46

0.74 to 2.18

0.60

− 0.24 to 1.42

 

1.64

0.92 to 2.36

0.47

− 0.36 to 1.30

0.17

2.49

0.097

LCQ Psych

1.95

0.92 to 2.99

0.80

− 0.42 to 2.01

 

2.43

1.39 to 3.46

0.50

− 0.72 to 1.71

0.19

3.36

0.046

LCQ Soc

1.91

1.00 to 2.81

0.96

− 0.09 to 2.00

 

2.30

1.39 to 3.20

0.96

− 0.09 to 2.00

0.14

1.84

0.174

VAS

-32.3

-52.1 to -12.4

-5.11

-27.0 to 16.8

 

-33.4

-53.2 to -13.5

-4.2

-26.1 to 17.1

0.11

2.16

0.103

logC5

1.12

0.53 to 1.78

0.41

− 0.41 to 0.97

 

--

--

--

--

0.13

2.54

0.094

UTC

-5.00

-7.47 to -2.53

-1.61

-4.34 to 1.11

 

--

--

--

--

0.15

5.08

0.037

  1. PT1 = 1-week post-treatment; PT2 = 3 weeks post-treatment; CI = confidence interval; LCQ = Leicester Cough Questionnaire; LCQPhys = LCQ Physical Domain; LCQPsych = LCQ Psychological Domain; LCQSoc = LCQ Social Domain; VAS = visual analogue scale of cough severity; logC5 = log form of dose that causes 5 or more coughs during cough challenge testing; N2p = partial eta squared effect size; UTC = urge-to-cough