Table 2 Univariable and multivariable regression analysis of the determinants of in-hospital antibiotic use

CRP in mg/L

1.04 [1.03; 1.05]

 < 0.001

1.04 [1.02; 1.06]

 < 0.001

Azithromycin MWF

9.31 [2.85; 30.44]

 < 0.001

12.11 [2.50; 58.61]

0.002

Body temperature in °C

3.05 [2.10; 4.43]

 < 0.001

5.13 [2.46; 10.70]

 < 0.001

Sputum volume

2.61 [1.58; 4.31]

 < 0.001

2.87 [1.24; 6.66]

0.014

BMI in kg/m²

0.95 [0.92; 0.98]

0.002

0.94 [0.89; 1.00]

0.043

Age in years

1.03 [1.01; 1.05]

0.003

1.04 [1.00; 1.08]

0.030

Maintenance theophylline

4.43 [1.01; 19.39]

0.048

7.05 [1.25; 39.83]

0.027

Sputum purulence

2.69 [1.54; 4.69]

 < 0.001

2.34 [0.96; 5.71]

0.061

Neutrophils count in /µL

1.00009 [1.00002; 1.00016]

0.008

1.00011 [0.99999; 1.00022]

0.064

Cancer

2.61 [1.32; 5.17]

0.006

2.60 [1.06; 6.40]

0.038

Sex

0.71 [0.47; 1.08]

0.113

0.54 [0.26; 1.12]

0.100

Inhaled corticosteroids

1.63 [1.07; 2.48]

0.022

1.75 [0.86; 3.55]

0.123

Intensive care unit

1.62 [0.80; 3.28]

0.183

2.76 [0.71; 10.65]

0.141