PROs | All COPD patients, N = 374 | Severity of airflow limitation based on PB-FEV1 (% predicted) | p-value | |||
---|---|---|---|---|---|---|
< 30% | 30–49% | 50–79% | ≥ 80% | |||
Number of COPD patients (% of total COPD patients) | ||||||
85 (22.7) | 142 (38.0) | 111 (29.7) | 36 (9.6) | |||
mMRC, score (mean ± SD, 95% CI) | 1.7 ± 1.3; 1.6–1.9 | 2.0 ± 1.4; 1.7–2.3 | 1.8 ± 1.3; 1.6–2.1 | 1.6 ± 1.1; 1.4–1.8 | 1.4 ± 1.1; 1.1–1.8 | 0.053 |
CAT, total score (mean ± SD, 95% CI) | 14.8 ± 10.1; 13.8–15.8 | 15.7 ± 11.1; 13.3–18.1 | 14.9 ± 10.1; 13.2–16.5 | 15.1 ± 9.9; 13.2–17.0 | 11.6 ± 8.1; 8.9–14.4 | 0.230 |
SGRQ-c, % (mean ± SD, 95% CI) Total Symptoms Activities Impact | 40.4 ± 26.0; 37.8–43.1 42.7 ± 26.4; 40.0–45.3 48.6 ± 30.4; 45.5–51.7 34.8 ± 29.4; 31.8–37.8 | 43.6 ± 29.2; 37.3–49.9 47.0 ± 29.2; 40.7–53.3 53.8 ± 32.5; 46.8–60.8 36.5 ± 32.9; 29.4–43.6 | 41.3 ± 27.1; 36.8–45.8 44.1 ± 27.8; 39.5–48.8 50.4 ± 32.1; 45.0–55.7 34.9 ± 29.2; 30.1–39.8 | 39.8 ± 23.7; 35.4–44.3 41.1 ± 22.7; 36.8–45.4 44.5 ± 27.2; 39.4–49.7 36.6 ± 28.8; 31.2–42.0 | 31.4 ± 18.5; 25.1–37.7 31.8 ± 21.4; 24.6–39.1 42.2 ± 26.1; 33.3–51.0 25.0 ± 21.5; 17.7–32.2 | 0.121 0.026 0.087 0.192 |