COPD exacerbations and patient-reported outcomes according to post-bronchodilator FEV1 – a post-hoc analysis of pooled data

Table 4 Pearson correlation and linear regression between PB-FEV_1, exacerbations, and PROs of COPD patients

Variables	R*	R ² *	Constant*	B*	SE*	r^#/beta*	t*	p-value^
PB-FEV₁% – Exacerbations mMRC CAT SGRQ-c	0.183 0.121 0.072 0.114	0.033 0.015 0.005 0.013	3.870 2.085 16.439 47.049	− 0.036 − 0.007 − 0.035 − 0.139	0.010 0.003 0.025 0.063	− 0.183 − 0.121 − 0.072 − 0.114	-3.588 -2.344 -1.401 -2.204	< 0.001 0.020 0.162 0.028
Exacerbations – mMRC CAT SGRQ-c	0.407 0.445 0.482	0.165 0.198 0.233	1.478 12.480 33.968	0.123 1.075 2.999	0.014 0.112 0.282	0.407 0.445 0.482	8.587 9.573 10.619	< 0.001 < 0.001 < 0.001
mMRC – CAT SGRQ-c	0.727 0.847	0.529 0.717	4.656 10.062	5.819 17.425	0.285 0.568	0.727 0.847	20.436 30.676	< 0.001 < 0.001
CAT – SGRQ-c	0.851	0.724	8.039	2.189	0.070	0.851	31.251	< 0.001

* value for linear regression
# value for Pearson correlation
^ value for both Pearson correlation and linear regression
Abbreviations: PB-FEV₁, post-bronchodilator forced expiratory volume in one second; PROs, patient-reported outcomes; COPD, chronic obstructive pulmonary disease; mMRC, modified Medical Research Council; CAT, COPD Assessment Tool; SGRQ-c, St George’s Respiratory Questionnaire for COPD; B, unstandardized beta; SE, standard error

ISSN: 1471-2466