Table 1 Characteristics of the enrolled studies. APP awake prone position, NR not reported, SpO2 transcutaneous oxygen saturation, FiO2 inspired oxygen fraction. SpO2 to FiO2 ratio was estimated by following formula S/F = 64 + 0.84×(P/F) if P/F were reported in the study
Study | Settings | Patient Number | Estimated baseline S/F, mmHg | Overall intubation rate, % | Daily APP duration, hour |
|---|---|---|---|---|---|
Alhazzani 2022 | ICU | 400 | 133.9 ± 52.5 | 37.3 | 4.8 (1.8 to 8.0) |
Ehrmann 2021 | ICU | 1121 | 148.2 ± 43.5 | 36.4 | 5.0 (1.6 to 8.8) |
Fralick 2022 | Non-ICU | 250 | 303.9 ± 18.4 | 4.4 | 6 (1.5 to 12.8) |
Gad 2021 | ICU | 30 | 163.45 ± 109.9 | 20.0 | each session last for 1 to 2 h according to patients to tolerability with 3-hs apart during waking hours. |
Jayakumar 2021 | ICU | 60 | 226.1 ± 164.8 | 13.3 | a minimum of 6-h in a day |
Johnson 2021 | Non-ICU | 30 | NR | 6.7 | 1.6 (0.2 to 3.1) |
Kharat 2021 | Non-ICU | 27 | 329.3 ± 56.0 | 0.0 | 4.9 ± 3.6 |
Rampon 2022 | Non-ICU | 293 | 396 (306–387) | 2.0 | NR |
Rosen 2021 | ICU | 75 | 160 ± 87.5 | 66.7 | 9.0 ± 4.6 (control group, 3 h) |
Taylor 2021 | Non-ICU | 40 | NR | 0.0 | 10 to 120 min per day |