Table 2 Biomarkers in sputum specimen at baseline
From: The effect of azithromycin on sputum inflammatory markers in bronchiectasis
Overall n = 54 | AZM n = 25 | Placebo n = 29 | P-value | |
|---|---|---|---|---|
ECP (ug) | 3.75 (8.8) | 3.8 (8.1) | 3.6 (9) | 0.828 |
Fractalkine (pg) | 0 (0) | 0 (0) | 0 (0) | 0.392 |
GCSF (pg) | 0 (100.2) | 0 (128.8) | 0 (26.1) | 0.307 |
GMCSF (pg) | 0 (0) | 0 (0) | 0 (0) | 1.000 |
GRO-α (pg) | 14 (297.9) | 13.9 (387) | 17 (170) | 0.668 |
IFN-γ (pg) | 0 (0) | 0 (0) | 0 (0) | 0.369 |
IL-10 (pg) | 0 (0) | 0 (0) | 0 (0) | 1.000 |
IL-12p70 (pg) | 0 (0) | 0 (0) | 0 (0) | 0.185 |
IL-13 (pg) | 0 (0) | 0 (0) | 0 (0) | 0.031 |
IL -17A (pg) | 0 (0) | 0 (0) | 0 (0) | 0.471 |
IL-1α (pg) | 285.3 (871.7) | 335.7 (660.3) | 285.3 (1071.9) | 0.869 |
IL-1β (ng) | 6.5 (22.0) | 6.4 (17.9) | 7.5 (41.8) | 0.735 |
IL-1RA (pg) | 606.7 (1716.7) | 549.9 (1993.2) | 606.7 (1578) | 0.842 |
IL-21 (pg) | 7.61 (62) | 3.1 (44) | 8.4 (90) | 0.503 |
IL-4 (pg) | 0 (0) | 0 (0) | 0 (3) | 0.737 |
IL-5 (pg) | 0 (0) | 0 (0) | 0 (0) | 0.879 |
IL-6 (pg) | 5.5 (548.5) | 0 (837.1) | 63.9 (504.8) | 0.623 |
IL-8 (ng) | 22.1 (84.4) | 25 (101.4) | 22.1 (70.3) | 0.381 |
IP-10 (pg) | 53.5 (149.2) | 42.6 (136.9) | 76.3 (149.2) | 0.695 |
MIP-1β (ng) | 5.7 (9.7) | 4.2 (6.5) | 7.2 (14.4) | 0.504 |
MIP-3α (pg) | 0 (69) | 0 (175) | 0 (64) | 0.496 |
MMP-9 (ng) | 178.0 (329.7) | 178 (316.9) | 177.1 (375.1) | 0.869 |
MPO (ug) | 76.31 (240.4) | 86.4 (178) | 53.3 (270.2) | 0.842 |
TNF-α (pg) | 129.9 (1334) | 238.4 (1019) | 129.9 (1841) | 0.854 |
VEGF (pg) | 1665.3 (3794.6) | 1221.3 (3789.3) | 1700.1 (3985.2) | 0.683 |