Table 3 Baseline sputum inflammatory profile grouped according to Pseudomonas aeruginosa or Haemophilus influenzae colonization
From: The effect of azithromycin on sputum inflammatory markers in bronchiectasis
Pseudomonas aeruginosa | Haemophilus influenzae | |||||
|---|---|---|---|---|---|---|
Yes (n = 10) | No (n = 44) | p-value | Yes (n = 16) | No (n = 38) | p-value | |
MPO (ug) | 87.5 (121.1) | 75.9 (264.4) | 0.373 | 249.9 (483.8) | 49.5 (110.3) | 0.004 |
ECP (ug) | 3.0 (7.8) | 4.3 (9.5) | 0.449 | 7.7 (17.7) | 2.6 (7.0) | 0.043 |
IP-10 (pg) | 19.3 (72.3) | 70.2 (162.7) | 0.180 | 77 (172.5) | 43 (122.6) | 0.133 |
MIP-1β (ng) | 2.2 (6.4) | 6.6 (10.9) | 0.084 | 9.7 (32.2) | 4.2 (8.2) | 0.022 |
VEGF (pg) | 567.9 (1327.7) | 1719.5 (4025.6) | 0.031 | 2261.7 (4656.8) | 1332.7 (2840.7) | 0.185 |
TNF-α (pg) | 78.8 (157) | 554.7 (1846) | 0.120 | 1334.2 (4014) | 37.1 (549) | 0.000 |
IL-1RA (pg) | 100.9 (2529.9) | 640.0 (1579.0) | 0.082 | 414.5 (920.3) | 616.4 (2686.4) | 0.405 |
IL-21 (pg) | 0.28 (18) | 16.3 (80) | 0.215 | 44.1 (99) | 0.0 (24) | 0.001 |
IL-8 (ng) | 5.6 (14.7) | 38.4 (98.9) | 0.010 | 82.3 (110.8) | 17.4 (65.1) | 0.036 |
IL-1β (ng) | 5.1 (7.4) | 7.5 (29.1) | 0.161 | 30.5 (58.7) | 3.7 (7.6) | 0.000 |
IL-6 (pg) | 0.0 (244.8) | 38.4 (637.8) | 0.341 | 6.5 (993.3) | 2.8 (547.2) | 0.935 |
GCSF (pg) | 0.0 (18.4) | 0.0 (129.9) | 0.440 | 0.0 (218.1) | 0.0 (67.2) | 0.647 |
GRO-α (pg) | 40 (177.9) | 15.5 (418.4) | 0.981 | 0.0 (129.6) | 23.7 (463.1) | 0.309 |
IL-1α (pg) | 98 (410) | 344.8 (945.4) | 0.160 | 888.5 (1072.3) | 176.3 (437.8) | 0.000 |
MIP-3α (pg) | 0.0 (20) | 0.0 (118) | 0.546 | 0.0 (1711) | 0.0 (42) | 0.309 |
MMP-9 (ng) | 64.7 (68.8) | 236.2 (455.1) | 0.001 | 242.2 (608.3) | 176.7 (306) | 0.415 |