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Fig. 9 | BMC Pulmonary Medicine

Fig. 9

From: The combination therapy of isomucronulatol 7-O-beta-glucoside (IMG) and CEP-9722 targeting ferroptosis-related biomarkers in non-small cell lung cancer (NSCLC)

Fig. 9

The effect of cell proliferation in NSCLC cell lines by using CEP-9722 and IMG. A The HAS synergy and antagonism of CEP-9722 and IMG in A549 cell. B The cell percentages of A549 treated with CEP-9722 and IMG. C The IC50 values of CEP-9722, RAF-265, Gefitinib, BMS-599626, and IMG for cell viability inhibition in lung cancer cell line A549 were determined. D, E Control group represents DMSO-treated cells. F The CCK8 assay of A549 cell treated with different drugs. G A549 cells were cultured with CEP-9722 and/or IMG. Analyzing the induced colony formation and calculate the colony formation. Data shown represent mean ± SD from three independent experiments. **p < 0.01; ***p < 0.001; ****p < 0.0001

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BMC Pulmonary Medicine

ISSN: 1471-2466

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