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Table 1 Baseline characteristics of COPD patients who incorrectly performed a critical step of a prescribed inhalation technique for any one inhaler device before receiving inhalation training by a pharmacist (N = 66)

From: Cognitive impairment according to Montreal Cognitive Assessment independently predicts the ability of chronic obstructive pulmonary disease patients to maintain proper inhaler technique

Characteristics

n = 66

Characteristics

n = 66

Age (years), (min, max)

73 ± 9 (51, 93)

Number of device models

 

Age (years)

 

1 device

19 (28.8)

  ≥ 65

52 (78.8)

2 devices

38 (57.6)

  < 65

14 (21.2)

3 devices

9 (13.6)

Sex: Male

63 (95.5)

Type of devices

 

BMI (kg/m2)

21.6 ± 3.9

pMDI only

16 (24.2)

Education level

 

pMDI + 1 DPI

36 (54.5)

 Lower education (≤ 6 years)

36 (54.5)

pMDI + 2 DPIs

9 (13.6)

 Higher education (> 6 years)

30 (45.5)

DPIs only

3 (4.5)

Smoking status

 

2 DPIs

2 (3.0)

 Never smokers

1 (1.5)

Duration of prescribed inhalers

 

 Ex-smokers

57 (86.4)

 ≤ 6 months

11 (16.7)

 Current smokers

8 (12.1)

 > 6 months

55 (83.3)

COPD duration (years)

 

Mean MoCA score (n = 57)

19.3 ± 4.8 (10, 28)

  < 1

8 (12.1)

MoCA scorec(n = 57)

 

 1—3

20 (30.3)

 ≤ 24 points

46 (80.7)

  > 3

38 (57.6)

 > 24 points

11 (19.3)

FEV1/FVC (%)

50.6 ± 11.3

 ≤ 16 points

16 (28.1)

Severity of COPDa

 

 > 16 points

41 (71.9)

 Mild

14 (21.2)

MoCA domain score, mean ± SD, (percentage score)d

 Moderate

32 (48.5)

Visuospatial/executive (5 points)

2.8 ± 1.4 (55.8)

 Severe

18 (27.3)

Naming (3 points)

2.8 ± 0.5 (94.7)

 Very severe

2 (3.0)

Attention (6 points)

4.2 ± 1.5 (70.2)

mMRC, median (IQR)

1.0 (0–2)

Language (3 points)

1.0 ± 1.1 (32.7)

 mean ± SD (min,max)

1.2 ± 1.3 (0, 4)

Abstraction (2 points)

1.2 ± 0.8 (58.8)

CAT, (min,max)

11.3 ± 8.0 (1, 33)

Delayed recall (5 points)

1.4 ± 1.6 (28.4)

Exacerbations in 1 yearb

20 (30.3)

Orientation (6 points)

5.4 ± 0.9 (89.8)

Previous inhaler education

62 (93.9)

  
  1. Data presented as number (percentage) or mean ± standard deviation (min, max) unless otherwise indicated
  2. aGOLD classification of COPD severity by post-bronchodilator FEV1% predicted, Mild (≥ 80), Moderate (50–79), Severe (30–49), Very Severe (< 30) [1]
  3. bFrequent exacerbations (≥ 2 moderate exacerbations) and/or ≥ 1 hospitalization in 1 year prior enrollment
  4. cMoCA score ≤ 24 points and ≤ 16 points are considered mild cognitive impairment (MCI) and dementia, respectively [23]
  5. dPercentage score = a mean percentage score calculated as a percentage of maximum possible score