Table 1 Baseline demographics of participants with normal spirometry, PRISm, and COPD
From: Longitudinal mortality of preserved ratio impaired spirometry in a middle-aged Asian cohort
Total (N = 7,526) | Fixed ratio | Lower limit of normal | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Normal (n = 6,387) | PRISm (n = 471) | COPD (n = 668) | P-value | Normal (n = 6,395) | PRISm (n = 487) | COPD (n = 644) | P-value | |||
Age (years) | 51.9 ± 8.6 | 51.2 ± 8.5 | 53.4 ± 8.4 | 57.7 ± 8.1 | < 0.001 | 51.5 ± 8.6 | 54.7 ± 8.6 | 53.8 ± 8.7 | < 0.001 | |
Age group | < 0.001 | |||||||||
40–49 years | 3,659 (48.6) | 3,320 (52.0) | 200 (42.5) | 139 (20.8) | 3,231 (50.5) | 177 (36.3) | 251 (39.0) | |||
50–59 years | 2,037 (27.1) | 1,697 (26.6) | 140 (29.7) | 200 (29.9) | 1,708 (26.7) | 144 (29.6) | 185 (28.7) | |||
60–69 years | 1,830 (24.3) | 1,370 (21.5) | 131 (27.8) | 329 (49.3) | 1,456 (22.8) | 166 (34.1) | 208 (32.3) | |||
Male | 3,597 (47.8) | 2,858 (44.8) | 248 (52.7) | 491 (73.5) | < 0.001 | 2,913 (45.6) | 271 (55.7) | 413 (64.1) | < 0.001 | |
BMI (kg/m2) | 24.7 ± 3.1 | 24.7 ± 3.0 | 24.9 ± 3.5 | 23.7 ± 2.9 | < 0.001 | 24.7 (3.1) | 24.8 (3.5) | 23.9 (3.0) | < 0.001 | |
BMI group | < 0.001 | < 0.001 | ||||||||
< 18.5 kg/m2 | 115 (1.5) | 80 (1.3) | 17 (3.6) | 18 (2.7) | 79 (1.2) | 18 (3.7) | 18 (2.8) | |||
18.5–22.9 kg/m2 | 2,156 (28.7) | 1,759 (27.5) | 121 (25.7) | 276 (41.3) | 1,783 (27.9) | 133 (27.3) | 240 (37.3) | |||
23.0–24.9 kg/m2 | 1,979 (26.3) | 1,714 (26.8) | 92 (19.5) | 173 (25.9) | 1,717 (26.9) | 92 (18.9) | 170 (26.4) | |||
≥ 25.0 kg/m2 | 3,276 (43.5) | 2,834 (44.4) | 241 (51.2) | 201 (30.1) | 2,816 (44.0) | 244 (50.1) | 216 (35.5) | |||
Smoking status | < 0.001 | < 0.001 | ||||||||
Never | 4,480 (59.5) | 4,009 (62.8) | 260 (55.2) | 211 (31.6) | 3,981 (62.3) | 250 (51.3) | 249 (38.7) | |||
Former | 1,209 (16.1) | 983 (15.4) | 82 (17.4) | 144 (21.6) | 1,006 (15.7) | 85 (17.5) | 118 (18.3) | |||
Current | 1,837 (24.4) | 1,395 (21.8) | 129 (27.4) | 313 (46.9) | 1,408 (22.0) | 152 (31.2) | 277 (43.0) | |||
Lung function | ||||||||||
FEV1% predicted | 96.9 ± 13.9 | 100.4 ± 11.1 | 73.3 ± 6.1 | 80.2 ± 14.1 | < 0.001 | 100.4 ± 11.1 | 73.4 ± 5.9 | 80.1 ± 14.3 | < 0.001 | |
FVC % predicted | 96.8 ± 13.1 | 98.5 ± 11.4 | 73.6 ± 8.7 | 97.5 ± 14.9 | < 0.001 | 98.4 ± 11.3 | 73.7 ± 8.5 | 98.7 ± 15.2 | < 0.001 | |
FEV1/FVC (%) | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.6 ± 0.1 | < 0.001 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.6 ± 0.1 | < 0.001 | |
Comorbidities | ||||||||||
HTN | 1,112 (14.8) | 917 (14.4) | 95 (20.2) | 100 (15.0) | 0.002 | 927 (14.5) | 105 (21.6) | 80 (12.4) | < 0.001 | |
DM | 469 (6.2) | 376 (5.9) | 44 (9.3) | 49 (7.3) | 0.005 | 382 (6.0) | 42 (8.6) | 45 (7.0) | 0.046 | |
CVD | 125 (1.7) | 93 (1.5) | 10 (2.1) | 22 (3.3) | 0.001 | 97 (1.5) | 13 (2.7) | 15 (2.3) | 0.060 | |