Table 5 Diagnostic value of different biomarkers in malignant pleural effusion
Group | CEA | Methylation | Combined |
|---|---|---|---|
Sensitivity(%) | 74.3 | 71.4 | 88.6 |
Specificity(%) | 97.0 | 84.8 | 81.8 |
Accuracy(%) | 85.3 | 77.9 | 85.3 |
PPV (%) | 96.3 | 83.3 | 83.8 |
NPV (%) | 78.0 | 73.7 | 87.1 |
Youden’s index | 0.71 | 0.56 | 0.70 |