From: Characteristics of idiopathic pulmonary fibrosis -associated cough. a case-control study
Measured variable | Total IPF-population (n=68) | IPF cc population (n=46) | IPF-population without cough (n=22) | p-value |
---|---|---|---|---|
Age | 67.0 (62.3–72.8) | 67.5 (64.7–70.0) | 67 (61.0–75.0) | 0.870 |
Gender (female) | 29 (42.6 %) | 26 (56.5%) | 3 (13.6 %) | 0.001 |
BMI (kg/m2) | 28.1 (26.4–31.5) | 27.9 (26.7–30.8) | 28.5 (26.4–30.6) | 0.911 |
Current smoker | 6 (8.8 %) | 5 (10.9 %) | 1 (4.5 %) | 0.390 |
Ever smoker | 42 (61.8 %) | 28 (60.9%) | 14 (63.6 %) | 0.826 |
FVC (% predicted) | 79.5 (72.3–88.0) | 78.50 (73.7–82.3) | 84.5 (77.0–91.25) | 0.098 |
DLCO (% predicted) | 64.0 (53.5–73.0) | 63.50 (58.3–68.0) | 64.0 (46.6–73.5) | 0.637 |
GAP Index | 3.00 (2.00–3.00) | 3.00 (2.00–3.00) | 3.00 (2.00–4.00) | 0.352 |
Sputum production | 5.0 (3.0–6.0) | 5.0 (3.0–6.0) | 6.0 (4.00–7.00) | 0.075 |
Cough response to paint or fumes | 6.0 (5.0–7.0) | 5.5 (5.0–7.0) | 6.0 (6.00–7.00) | 0.057 |
Cough disturbing sleep | 6.0 (5.0–7.0) | 5.5 (4.0–6.0) | 7.0 (6.00–7.00) | 0.000 |
Cough bout frequency per day | 5.0 (3.0–6.0) | 4.0 (3.0–6.0) | 6.0 (5.75–7.00) | 0.000 |
LCQ total score | 16.9 (13.4–18.9) | 14.8 (11.5–18.1) | 18.2 (16.4–19.4) | 0.002 |
LCQ physical domain | 5.4 (4.5–6.1) | 4.9 (3.9–6.1) | 5.9 (5.1–6.4) | 0.003 |
LCQ psychological domain | 5.2 (4.1–6.3) | 4.6 (3.7–5.9) | 6.0 (5.0–6.7) | 0.002 |
LCQ social domain | 5.8 (4.8–6.7) | 5.5 (3.7–6.5) | 6.4 (5.8–6.8) | 0.006 |