Skip to main content

Table 2 Morphologic characteristics of pulmonary cysts on initial CT and temporal changes in cyst characteristics between initial CT and last CT

From: Progression of pulmonary cysts in Birt-Hogg-Dubé syndrome: longitudinal thoracic computed tomography study with quantitative assessment

 

Initial CT

Last CT

Difference

p-value

Largest cyst (right lung)

25.1 ± 15.3 mm

26.1 ± 15.5 mm

1.0 (0.42,1.64)

0.002

Largest cyst (left lung)

25.0 ± 15.3 mm

25.8 ± 15.6 mm

0.8 (-0.49,1.09)

 < 0.001

Cyst number

   

0.28

 ≤ 50

67.4% (29)

60.5% (26)

  

 50–100

25.6% (11)

27.9% (12)

  

 ≥ 100

7.0% (3)

11.6% (5)

  

Cyst shape

   

0.50

 Round/ovoid

14.0% (6)

9.3% (4)

  

 Lentiform

0.0 (0)

0.0 (0)

  

 Irregular

86.0% (37)

90.73% (39)

  

 Septated

0.0% (0)

0.0% (0)

  

Location of largest cyst

   

1.00

 Subpleural

83.7% (35)

79.1% (33)

  

 within lung parenchyma

16.3% (7)

20.9% (9)

  

Cyst wall: identifiable

100.0% (43)

100.0% (43)

 

1.00

Distribution

   

1.00

 Upper

0.0% (0)

0.0% (0)

 

1.00

 Lower

20.9% (9)

20.9% (9)

 

1.00

 Diffuse

79.1% (34)

79.1% (34)

 

1.00

Fissural cyst

97.7% (42)

97.7% (42)

 

1.00

Subpleural cyst

100.0% (43)

100.0% (43)

 

1.00

Encircling bronchovascular bundle (air-cuff sign)

62.8% (27)

79.1% (34)

 

0.02

  1. Numbers within parenthesis indicate the number of patients
  2. Statistics on the change in cyst size were calculated using the paired t-test after converting into 1-year change rate due to the difference between intervals according to CT
  3. A paired t-test was performed for continuous variables, and exact McNemar's test was performed for categorical variables