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Table 7 Value of vascular endothelial injury markers (sTM and vWF) in screening T2DM + PE

From: Changes and significance of vascular endothelial injury markers in patients with diabetes mellitus and pulmonary thromboembolism

Markers

Cutoff

AUC

P

Sensitivity (%)

Specificity (%)

95% CI

Youden index

sTM

676.68 pg/mL

0.973 ± 0.013

< 0.001

100

86.7

0.947–0.999

0.867

vWF

13.75 ng/mL

0.954 ± 0.022

< 0.001

90.0

95.0

0.911–0.998

0.85

sTM + vWF

-

0.993 ± 0.007

< 0.001

100

96.7

0.980–1.000

0.967

PO2

85.2 mmHg

0.888 ± 0.047

< 0.001

86.7 

86.7 

0.796–0.981

0.734

  1. AUC Area under the curve, sTM Soluble thrombomodulin, vWF Von Willebrand factor, CI Confidence interval