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Asthma and allergic disorders

Section edited by Joerg Mattes

This section concerns all aspects of asthma and allergic disorders including, but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Content type: Research article

    Vitamin D deficiency has been linked to an increased risk of asthma. This study aimed to quantify the effect of early life vitamin D status on asthma and wheeze later in life.

    Authors: Song-Ying Shen, Wan-Qing Xiao, Jin-Hua Lu, Ming-Yang Yuan, Jian-Rong He, Hui-Min Xia, Xiu Qiu, Kar Keung Cheng and Kin Bong Hubert Lam

    Citation: BMC Pulmonary Medicine 2018 18:120

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  2. Content type: Research article

    Interleukin-5 (IL-5) antibodies represent a promising therapeutic option for patients with severe eosinophilic asthma. To date, no official treatment response criteria exist. In this study, simple criteria for...

    Authors: Nora Drick, Benjamin Seeliger, Tobias Welte, Jan Fuge and Hendrik Suhling

    Citation: BMC Pulmonary Medicine 2018 18:119

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  3. Content type: Research article

    Sputum induction is an important noninvasive method for analyzing bronchial inflammation in patients with asthma and other respiratory diseases. Most frequently, ultrasonic nebulizers are used for sputum induc...

    Authors: Sinem Koc-Günel, Ralf Schubert, Stefan Zielen and Martin Rosewich

    Citation: BMC Pulmonary Medicine 2018 18:115

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  4. Content type: Research article

    The natural history of airway inflammation and symptoms in occupations at risk of asthma is still not fully understood. We aimed to study the evolution during apprenticeship of inflammation markers, bronchial ...

    Authors: Valérie Demange, Denis Zmirou-Navier, Abraham Bohadana and Pascal Wild

    Citation: BMC Pulmonary Medicine 2018 18:113

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  5. Content type: Research article

    Multiple factors are involved in asthma exacerbations, including environmental exposure and viral infections. We aimed to assess the association between severe asthma exacerbations, acute respiratory viral inf...

    Authors: Lusmaia Damaceno Camargo Costa, Paulo Augusto Moreira Camargos, Paul L. P. Brand, Fabíola Souza Fiaccadori, Menira Borges de Lima Dias e Souza, Divina das Dôres de Paula Cardoso, Ítalo de Araújo Castro, Ruth Minamisava and Paulo Sérgio Sucasas da Costa

    Citation: BMC Pulmonary Medicine 2018 18:109

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  6. Content type: Research article

    Incorrect inhaler technique is a common cause of poor asthma control. This two-phase pragmatic study evaluated inhaler technique mastery and maintenance of mastery with DuoResp® (budesonide-formoterol [BF]) Sp...

    Authors: David B. Price, Vicky Thomas, P. N. Richard Dekhuijzen, Sinthia Bosnic-Anticevich, Nicolas Roche, Federico Lavorini, Priyanka Raju, Daryl Freeman, Carole Nicholls, Iain R. Small, Erika Sims, Guilherme Safioti, Janice Canvin and Henry Chrystyn

    Citation: BMC Pulmonary Medicine 2018 18:107

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  7. Content type: Research article

    An increasing number of studies using primary human bronchial epithelial cells (BECs) have reported intrinsic differences in the expression of several genes between cells from asthmatic and non-asthmatic donor...

    Authors: Stephen R. Reeves, Kaitlyn A. Barrow, Maria P. White, Lucille M. Rich, Maryam Naushab and Jason S. Debley

    Citation: BMC Pulmonary Medicine 2018 18:91

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  8. Content type: Research article

    Asthma is a common chronic respiratory disease leading to morbidity, mortality and impaired quality of life worldwide. Information on asthma prevalence in the Middle East is fragmented and relatively out-dated...

    Authors: Hesham Tarraf, Omur Aydin, Dilsad Mungan, Mohammad Albader, Bassam Mahboub, Adam Doble, Aaicha Lahlou, Luqman Tariq, Fayaz Aziz and Abdelkader El Hasnaoui

    Citation: BMC Pulmonary Medicine 2018 18:68

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  9. Content type: Research article

    Although pre-puberty asthma is more prevalent in males, after puberty through middle-age, asthma is more prevalent in females. The surge of sex hormones with puberty might explain this gender switch.

    Authors: Mark D. DeBoer, Brenda R. Phillips, David T. Mauger, Joe Zein, Serpil C. Erzurum, Anne M. Fitzpatrick, Benjamin M. Gaston, Ross Myers, Kristie R. Ross, James Chmiel, Min Jie Lee, John V. Fahy, Michael Peters, Ngoc P. Ly, Sally E. Wenzel, Merritt L. Fajt…

    Citation: BMC Pulmonary Medicine 2018 18:58

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  10. Content type: Case report

    Allergic bronchopulmonary aspergillosis (ABPA) is an allergic pulmonary disease comprising a complex hypersensitivity reaction to Aspergillus fumigatus. Clinical features of ABPA are wheezing, mucoid impaction, a...

    Authors: Takeshi Terashima, Taro Shinozaki, Eri Iwami, Takahiro Nakajima and Tatsu Matsuzaki

    Citation: BMC Pulmonary Medicine 2018 18:53

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  11. Content type: Case report

    Mortality related to asthma has decreased worldwide since the introduction of inhaled corticosteroid therapy in the past decades. However, there are still some asthma fatalities identified mainly in population...

    Authors: Thais Mauad, Felipe B. P. do Nascimento, Marisa Dolhnikoff, Milena C. M. Picka and Paulo H. N. Saldiva

    Citation: BMC Pulmonary Medicine 2018 18:50

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  12. Content type: Research article

    Thus far, no algorithms have been developed to automatically extract patients who meet Asthma Predictive Index (API) criteria from the Electronic health records (EHR) yet. Our objective is to develop and valid...

    Authors: Harsheen Kaur, Sunghwan Sohn, Chung-Il Wi, Euijung Ryu, Miguel A. Park, Kay Bachman, Hirohito Kita, Ivana Croghan, Jose A. Castro-Rodriguez, Gretchen A. Voge, Hongfang Liu and Young J. Juhn

    Citation: BMC Pulmonary Medicine 2018 18:34

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  13. Content type: Research article

    Bronchial thermoplasty (BT) is a non-pharmacological intervention for severe asthma whose mechanism of action is not completely explained by a reduction of airway smooth muscle (ASM). In this study we analyzed...

    Authors: N. Facciolongo, A. Di Stefano, V. Pietrini, C. Galeone, F. Bellanova, F. Menzella, N. Scichilone, R. Piro, G. L. Bajocchi, B. Balbi, L. Agostini, P. P. Salsi, D. Formisano and M. Lusuardi

    Citation: BMC Pulmonary Medicine 2018 18:29

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  14. Content type: Research article

    Postoperative pulmonary complications (PPC) in patients with pulmonary diseases remain to be resolved clinical issue. However, most evidence regarding PPC has been established more than 10 years ago. Therefore...

    Authors: Takanori Numata, Katsutoshi Nakayama, Satoko Fujii, Yoko Yumino, Nayuta Saito, Masahiro Yoshida, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara…

    Citation: BMC Pulmonary Medicine 2018 18:4

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  15. Content type: Research article

    Annexin-A1 (ANXA1) is a glucocorticoid-induced protein with multiple actions in the regulation of inflammatory cell activation. The anti-inflammatory protein ANXA1 and its N-formyl peptide receptor 2 (FPR2) ha...

    Authors: Sun-Hye Lee, Pureun-Haneul Lee, Byeong-Gon Kim, Hyun-Jeong Seo, Ae-Rin Baek, Jong-Sook Park, June-Hyuk Lee, Sung-Woo Park, Do-Jin Kim, Choon-Sik Park and An-Soo Jang

    Citation: BMC Pulmonary Medicine 2018 18:1

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  16. Content type: Research article

    We previously reported that the ILVBL gene on chromosome 19p13.1 was associated with the risk for aspirin-exacerbated respiratory disease (AERD) and the percent decline of forced expired volume in one second (FEV...

    Authors: Hun Soo Chang, Jong Sook Park, Ho Sung Lee, Jiwon Lyu, Ji-Hye Son, Inseon S. Choi, Hyoung Doo Shin and Choon-Sik Park

    Citation: BMC Pulmonary Medicine 2017 17:210

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  17. Content type: Research article

    Previous studies have indicated that chitinase 3-like 1 (CHI3L1) gene rs4950928 polymorphism and acidic mammalian chitinase (AMCase or CHIA) gene rs10494132 polymorphism are associated with the risk of asthma....

    Authors: Yanting Zhu, Xin Yan, Cui Zhai, Lan Yang and Manxiang Li

    Citation: BMC Pulmonary Medicine 2017 17:193

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  18. Content type: Research article

    Gene expression changes in the structural cells of the airways are thought to play a role in the development of asthma and airway hyperresponsiveness. This includes changes to smooth muscle contractile machine...

    Authors: Christopher D. Pascoe, Ma’en Obeidat, Bryna A. Arsenault, Yunlong Nie, Stephanie Warner, Dorota Stefanowicz, Samuel J. Wadsworth, Jeremy A. Hirota, S. Jasemine Yang, Delbert R. Dorscheid, Chris Carlsten, Tillie L. Hackett, Chun Y. Seow and Peter D. Paré

    Citation: BMC Pulmonary Medicine 2017 17:189

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  19. Content type: Research article

    Inhaled corticosteroids are recommended as the first-line controller medication for childhood asthma owing to their multiple clinical benefits. However, heterogeneity in the response towards these drugs remain...

    Authors: Yi-Fan Wu, Ming-Wei Su, Bor-Luen Chiang, Yao-Hsu Yang, Ching-Hui Tsai and Yungling L. Lee

    Citation: BMC Pulmonary Medicine 2017 17:176

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