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Asthma and allergic disorders

This section concerns all aspects of asthma and allergic disorders including, but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Angiopoietin-1 (Ang-1) is an essential mediator of angiogenesis that establishes vascular integrity, and angiopoietin-2 (Ang-2) acts as its natural inhibitor. We considered that angiopoietin might be important...

    Authors: Kuk-Young Moon, PuReun-HaNeul Lee, Sung-Woo Park, Choon-Sik Park and An-Soo Jang

    Citation: BMC Pulmonary Medicine 2014 14:143

    Content type: Research article

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  2. Air pollution has many negative health effects on the general population, especially children, subjects with underlying chronic disease and the elderly. The aims of this study were to evaluate the effects of t...

    Authors: Susanna Esposito, Carlotta Galeone, Mara Lelii, Benedetta Longhi, Beatrice Ascolese, Laura Senatore, Elisabetta Prada, Valentina Montinaro, Stefano Malerba, Maria Francesca Patria and Nicola Principi

    Citation: BMC Pulmonary Medicine 2014 14:130

    Content type: Research article

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  3. Serum KL-6 is a useful biomarker for the diagnosis of interstitial lung diseases (ILD). However, KL-6 has not been used to discriminate different types of ILD. Serum KL-6 concentrations can vary depending on a...

    Authors: Hiroshi Ohnishi, Shintaro Miyamoto, Shigeo Kawase, Tetsuya Kubota and Akihito Yokoyama

    Citation: BMC Pulmonary Medicine 2014 14:129

    Content type: Research article

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  4. Nitric oxide can be measured at multiple flow rates to determine proximal (maximum airway nitric oxide flux; JawNO) and distal inflammation (alveolar nitric oxide concentration; CANO). The main aim was to study t...

    Authors: Olaia Sardón, Paula Corcuera, Ane Aldasoro, Javier Korta, Javier Mintegui, José I Emparanza and Eduardo G Pérez-Yarza

    Citation: BMC Pulmonary Medicine 2014 14:126

    Content type: Research article

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  5. Eotaxin proteins are a potential therapeutic target in treating the peribronchial eosinophilia associated with allergic airway diseases. Since inflammation is often associated with an increased generation of r...

    Authors: In-Hee Cho, Ju-Hyun Gong, Min-Kyung Kang, Eun-Jung Lee, Jung Han Yoon Park, Sang-Jae Park and Young-Hee Kang

    Citation: BMC Pulmonary Medicine 2014 14:122

    Content type: Research article

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  6. In healthy lungs, deposited micrometer-sized particles are efficiently phagocytosed by macrophages present on airway surfaces; however, uptake of nanoparticles (NP) by macrophages appears less effective and is...

    Authors: Marianne Geiser, Christoph Wigge, Melanie L Conrad, Sylvie Eigeldinger-Berthou, Lisa Künzi, Holger Garn, Harald Renz and Marcus A Mall

    Citation: BMC Pulmonary Medicine 2014 14:116

    Content type: Research article

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  7. Inhaled corticosteroids are a mainstay of therapy for persistent asthma, but suboptimal adherence with twice-daily use is widespread. Fluticasone furoate (FF) is a new inhaled corticosteroid (ICS) suitable for...

    Authors: Ashley Woodcock, Jan Lötvall, William W Busse, Eric D Bateman, Sally Stone, Anna Ellsworth and Loretta Jacques

    Citation: BMC Pulmonary Medicine 2014 14:113

    Content type: Research article

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  8. The impact of air pollution on the respiratory system has been estimated on the basis of respiratory symptoms and lung function. However; few studies have compared lung inflammation in healthy and asthmatics c...

    Authors: Benigno Linares Segovia, Gabriela Cortés Sandoval, Norma Amador Licona, Juan Manuel Guízar Mendoza, Estela Núñez Lemus, Diana Olivia Rocha Amador, Xóchitl Sofía Ramírez Gómez and Rebeca Monroy Torres

    Citation: BMC Pulmonary Medicine 2014 14:111

    Content type: Research article

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  9. Improvements in asthma diagnosis and management require deeper understanding of the heterogeneity of the complex airway inflammation. We hypothesise that differences in the two major inflammatory phenotypes of...

    Authors: Maria Bergquist, Sofia Jonasson, Josephine Hjoberg, Göran Hedenstierna and Jörg Hanrieder

    Citation: BMC Pulmonary Medicine 2014 14:110

    Content type: Research article

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  10. Many asthmatic women complain of symptom exacerbations in particular periods, i.e. during pregnancy and menstrual cycles (perimenstrual asthma: PMA)". The goal of this study was to study the effect of the lute...

    Authors: Maria Matteis, Francesca Polverino, Giuseppe Spaziano, Fiorentina Roviezzo, Carlo Santoriello, Nikol Sullo, Maria Rosaria Bucci, Francesco Rossi, Mario Polverino, Caroline A Owen and Bruno D’Agostino

    Citation: BMC Pulmonary Medicine 2014 14:108

    Content type: Research article

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  11. Chronic eosinophilic pneumonia (CEP) is characterized by chronic eosinophilic infiltration of the lung. It is dramatically responsive to corticosteroid treatment, but symptoms and radiopacities recur frequentl...

    Authors: Ji Young Park, Taehoon Lee, Hongyeul Lee, Yeon Joo Lee, Jong Sun Park, Young-Jae Cho, Ho Il Yoon, Jae Ho Lee and Choon-Taek Lee

    Citation: BMC Pulmonary Medicine 2014 14:81

    Content type: Research article

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  12. Bronchial asthma influences some chronic diseases such as coronary heart disease, diabetes mellitus, and hypertension, but the impact of asthma on vital diseases such as chronic kidney disease is not yet verif...

    Authors: Hui-Ling Huang, Shinn-Ying Ho, Chien-Hsun Li, Fang-Ying Chu, Li-Ping Ciou, Hua-Chin Lee, Wen-Liang Chen and Nian-Sheng Tzeng

    Citation: BMC Pulmonary Medicine 2014 14:80

    Content type: Research article

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  13. While reviews have been published on asthma management in pregnant women, none has examined the effectiveness of non-pharmacological healthcare interventions for optimizing asthma management in pregnant women....

    Authors: Elida Zairina, Kay Stewart, Michael J Abramson and Johnson George

    Citation: BMC Pulmonary Medicine 2014 14:46

    Content type: Research article

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  14. Lobular Capillary Hemangioma (LCH) is a benign tumour that is known to be hormone responsive and have a relatively high incidence during pregnancy, the most common site being the gingival surfaces. A tracheal ...

    Authors: Shivesh Prakash, Shailesh Bihari and Ubbo Wiersema

    Citation: BMC Pulmonary Medicine 2014 14:41

    Content type: Case report

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  15. Asthma and allergies are world-wide common chronic diseases among children and young people. Little information is available about the prevalence of these diseases in rural areas of Latin America. This study a...

    Authors: María Teresa Solis Soto, Armando Patiño, Dennis Nowak and Katja Radon

    Citation: BMC Pulmonary Medicine 2014 14:40

    Content type: Research article

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  16. Chronic airway diseases, like asthma or COPD, are characterized by excessive acetylcholine release and airway remodeling. The aim of this study was to investigate the long-term effect of muscarinic agonists on...

    Authors: Rodopi Stamatiou, Efrosini Paraskeva, Anna Vasilaki, Ilias Mylonis, Paschalis Adam Molyvdas, Konstantinos Gourgoulianis and Apostolia Hatziefthimiou

    Citation: BMC Pulmonary Medicine 2014 14:39

    Content type: Research article

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  17. Pneumonitis is a rare complication of bacillus Calmette-Guerin (BCG) immunotherapy seen in patients with urothelial cancer following the repeated administration of BCG. However, no case of BCG-induced pleurisy...

    Authors: Makoto Tobiume, Tsutomu Shinohara, Takahira Kuno, Shinji Mukai, Keishi Naruse, Nobuo Hatakeyama and Fumitaka Ogushi

    Citation: BMC Pulmonary Medicine 2014 14:35

    Content type: Case report

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  18. Endotoxins stimulate T helper 1 cell maturation and send a negative signal to T helper 2 polarisation. This causes a decrease IgE levels and prevents atopy (Hygiene hypothesis). It is shown that this response ...

    Authors: Füsun Şahin, Pınar Yıldız, Ayşegül Kuskucu, Mert Ahmet Kuskucu, Nilgün Karaca and Kenan Midilli

    Citation: BMC Pulmonary Medicine 2014 14:20

    Content type: Research article

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  19. There is limited information on the causes of death in asthma patients.

    Authors: Jose Gregorio Soto-Campos, Vicente Plaza, Joan B Soriano, Carlos Cabrera-López, Carlos Almonacid-Sánchez, Rosa Vazquez-Oliva, Jose Serrano, Aitor Ballaz-Quincoces, Alicia Padilla-Galo and Vanessa Santos

    Citation: BMC Pulmonary Medicine 2013 13:73

    Content type: Research article

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  20. The fraction of exhaled nitric oxide (FeNO) has been suggested as a non-invasive marker of eosinophilic inflammation in asthma, but lately rather as a biomarker of atopy than of asthma itself. Asthma after bro...

    Authors: Ingvild Bruun Mikalsen, Thomas Halvorsen and Knut Øymar

    Citation: BMC Pulmonary Medicine 2013 13:66

    Content type: Research article

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  21. Airway epithelial cells provide a protective barrier against environmental particles including potential pathogens. Epithelial repair in response to tissue damage is abnormal in asthmatic airway epithelium in ...

    Authors: Aleksandra Szczepankiewicz, Peter M Lackie and John W Holloway

    Citation: BMC Pulmonary Medicine 2013 13:63

    Content type: Research article

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  22. It has been suggested that smoking asthmatics benefit less from corticosteroid treatment than never-smoking asthmatics. We investigated differences in blood and sputum inflammatory profiles between ex-, curren...

    Authors: Eef D Telenga, Huib A M Kerstjens, Nick H T ten Hacken, Dirkje S Postma and Maarten van den Berge

    Citation: BMC Pulmonary Medicine 2013 13:58

    Content type: Research article

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  23. It remains unclear to what extent asthma in adults is linked to allergic rhinitis (AR), gastroesophageal reflux disease (GERD), and acetylsalicylic acid exacerbated respiratory disease (AERD), and how these co...

    Authors: Henriette Steppuhn, Ute Langen, Christa Scheidt-Nave and Thomas Keil

    Citation: BMC Pulmonary Medicine 2013 13:46

    Content type: Research article

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  24. The majority of the global population cannot afford existing asthma pharmacotherapy. Physical training as an airway anti-inflammatory therapy for asthma could potentially be a non-invasive, easily available, a...

    Authors: Smita Pakhale, Vanessa Luks, Andrew Burkett and Lucy Turner

    Citation: BMC Pulmonary Medicine 2013 13:38

    Content type: Research article

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  25. There is little data on the effect of exercise on markers of airway inflammation in human asthmatics. The main objective of this review is to determine the effects of physical training on markers of airway inf...

    Authors: Vanessa Luks, Andrew Burkett, Lucy Turner and Smita Pakhale

    Citation: BMC Pulmonary Medicine 2013 13:24

    Content type: Research article

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  26. Acute asthma attacks remain a frequent cause of emergency department (ED) visits and hospital admission. Many factors encourage patients to seek asthma treatment at the emergency department. These factors may ...

    Authors: Hamdan AL-Jahdali, Ahmed Anwar, Abdullah AL-Harbi, Salim Baharoon, Rabih Halwani, Abdulllah Al Shimemeri and Saleh Al-Muhsen

    Citation: BMC Pulmonary Medicine 2012 12:80

    Content type: Research article

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