Skip to main content

Cancer

Section edited by Montserrat Sanchez Cespedes

This section concerns all aspects of lung cancer including, but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

Page 1 of 3

  1. Long noncoding RNA POU class 3 homeobox 3 (POU3F3) is upregulated in esophageal squamous-cell carcinomas. The present study aimed to investigate the role of POU3F3 in non-small cell lung cancer (NSCLC).

    Authors: Qigang Zeng, Yong Dai, Chenxia Duan, Rong Zeng, Qingxiang Zeng and Chengong Wei

    Citation: BMC Pulmonary Medicine 2020 20:185

    Content type: Research article

    Published on:

  2. Tumor necrosis factor (TNF) has been investigated to be correlated with the occurrence and progression of lung cancer. This investigation was to assess the efficacy and safety of recombinant mutant human tumor...

    Authors: Tian Fu, Yong Lin, Qingdi Zeng, Wei Yao and Liping Han

    Citation: BMC Pulmonary Medicine 2020 20:175

    Content type: Research article

    Published on:

  3. Lung cancer is frequently situated peripherally in the upper lobes of the lung. Acquiring adequate tissue from this difficult-to-reach area remains a challenge. Transbronchial cryobiopsy (TBCB) has the ability...

    Authors: Sze Shyang Kho, Chan Sin Chai, Larry Ellee Nyanti, Adam Malik bin Ismail and Siew Teck Tie

    Citation: BMC Pulmonary Medicine 2020 20:158

    Content type: Case report

    Published on:

  4. Long non-coding RNA (lncRNA) Wilms Tumor 1 Associated Protein Pseudogene 1 (WTAPP1) has been reported to be a critical player in the angiogenesis and migration of endothelial progenitor cells, while its involv...

    Authors: Li Zhang, Chengyan Jin, Guiyun Yang, Bin Wang, Peiyan Hua and Yan Zhang

    Citation: BMC Pulmonary Medicine 2020 20:153

    Content type: Research article

    Published on:

  5. Endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) has been become an important procedure for the diagnosis and staging of lung cancer. Our research identified the effects of differen...

    Authors: Youzu Xu, Jian Lin, Meifang Chen, Haihong Zheng and Jiaxi Feng

    Citation: BMC Pulmonary Medicine 2020 20:140

    Content type: Research article

    Published on:

  6. Various host factors can promote pneumonia susceptibility of lung cancer patients. However, data about risk factors for pneumonia in lung cancer patients receiving active treatments such as chemotherapy, radio...

    Authors: Jung Won Heo, Chang Dong Yeo, Chan Kwon Park, Sung Kyoung Kim, Ju Sang Kim, Jin Woo Kim, Seung Joon Kim, Sang Haak Lee and Hye Seon Kang

    Citation: BMC Pulmonary Medicine 2020 20:117

    Content type: Research article

    Published on:

  7. Appropriate management of lung nodules detected incidentally or through lung cancer screening can increase the rate of early-stage diagnoses and potentially improve treatment outcomes. However, the implementat...

    Authors: Gregory P. LeMense, Ernest A. Waller, Cheryl Campbell and Tyler Bowen

    Citation: BMC Pulmonary Medicine 2020 20:115

    Content type: Research article

    Published on:

  8. The involvement of lncRNA FEZF1-AS1 has been analyzed in many types of cancers, while its roles in non-small cell lung cancer (NSCLC) remains unclear. We then explored the role of FEZF1-AS1 in NSCLC.

    Authors: Shangxiao Huang, Chunjun Li, Jianfeng Huang, Penghui Luo, Dunchang Mo and Hanlei Wang

    Citation: BMC Pulmonary Medicine 2020 20:110

    Content type: Research article

    Published on:

  9. Immune checkpoint inhibitors (ICIs) are the standard treatment for non-small cell lung cancer. The unique adverse events that can arise after treatment with ICIs are known as immune-related adverse events (irA...

    Authors: Takeshi Terashima, Eri Iwami, Takashi Shimada, Aoi Kuroda, Tatsu Matsuzaki, Takahiro Nakajima, Aya Sasaki and Keisuke Eguchi

    Citation: BMC Pulmonary Medicine 2020 20:104

    Content type: Case report

    Published on:

  10. The prognostic value of elevated pretreatment platelet counts remains controversial in lung cancer patients. We performed the present meta-analysis to determine its precise role in these patients.

    Authors: Yuan Yuan, Hai Zhong, Liang Ye, Qian Li, Surong Fang, Wei Gu and Yingying Qian

    Citation: BMC Pulmonary Medicine 2020 20:96

    Content type: Research article

    Published on:

  11. Malignant melanoma (MM) generally presents as a primary neoplasm of the skin, and most MM cases of the respiratory system are metastatic. Primary MM of the lung (PMML) is quite rare, and its diagnosis is relat...

    Authors: Shuangshuang Deng, Xiaobo Sun, Zhen Zhu, Jingjing Lu, Guanghua Wen, Xuejiao Chang, Hui Gao, Yanfei Hua, Lumei Wang and Jinli Gao

    Citation: BMC Pulmonary Medicine 2020 20:94

    Content type: Case report

    Published on:

  12. Kartagener syndrome, an autosomal recessive disorder with a triad of chronic sinusitis, bronchiectasis, and situs inversus, is characterized by recurrent respiratory tract infections and chronic inflammation o...

    Authors: Yoshiaki Nagai, Nobuyuki Koyama, Yuki Iwai, Hiroyoshi Tsubochi, Masahiro Hiruta, Yoshiko Mizushina, Shinichiro Koyama, Yuichi Ishikawa and Koichi Hagiwara

    Citation: BMC Pulmonary Medicine 2020 20:93

    Content type: Case report

    Published on:

  13. The most prevalent complication of percutaneous lung biopsy is pneumothorax (PNX). A routine immediate post-procedure CT scan (ICT) to spot PNX is done in many centers. However, the diagnostic yield of this pr...

    Authors: Rafael Y. Brzezinski, Ifat Vigiser, Irina Fomin, Lilach Israeli, Shani Shenhar-Tsarfaty and Amir Bar-Shai

    Citation: BMC Pulmonary Medicine 2020 20:91

    Content type: Research article

    Published on:

  14. Synchronous multiple primary lung cancers (sMPLC) are rare forms of lung cancer, and their diagnosis remains as a significant challenge. Distinguishing sMPLC from advanced disease is important as their prognos...

    Authors: Yang Song, Ziqi Jia, Pancheng Wu, Weiwei Wang, Qiuxiang Ou, Hua Bao, Man Yu, Xue Wu, Peng Liu, Naixin Liang, Shuyang Zhang and Shanqing Li

    Citation: BMC Pulmonary Medicine 2020 20:80

    Content type: Case report

    Published on:

  15. Malignant tumors are risk factors for a pulmonary embolism (PE), and a PE caused by a tumor is not uncommon. Primary pleural squamous cell carcinoma (PPSCC) is a rare malignancy; thus, a related PE is extremel...

    Authors: Zhongzhong Chen, Tingting Feng, Meng Wang, Xingxiang Xu, Yuxiu Wang, Yiran Li and Lingfeng Min

    Citation: BMC Pulmonary Medicine 2020 20:75

    Content type: Case report

    Published on:

  16. Lung cancer is one of the most common co-morbid conditions in patients with idiopathic pulmonary fibrosis (IPF) and negatively affects the prognosis of IPF; Current guidelines for the management of IPF do not ...

    Authors: Weirong Ma, Hui Li, Zhigang Tian, Shaojin Wang, Xiwei Zheng and Jia Hou

    Citation: BMC Pulmonary Medicine 2020 20:69

    Content type: Case report

    Published on:

  17. Malignant central airway obstruction (MCAO) occurs in 20–30% of patients with primary pulmonary malignancy. Although bronchoscopic intervention is widely performed to treat MCAO, little data exist on the progn...

    Authors: Bo-Guen Kim, Beomsu Shin, Boksoon Chang, Hojoong Kim and Byeong-Ho Jeong

    Citation: BMC Pulmonary Medicine 2020 20:54

    Content type: Research article

    Published on:

  18. congenital pulmonary airway malformation (CPAM) is the most frequent congenital lung disorder. CPAM type 1 is the most common subtype, typically having a cystic radiological and histological appearance. Mucino...

    Authors: Timco Koopman, Bart L. Rottier, Arja ter Elst and Wim Timens

    Citation: BMC Pulmonary Medicine 2020 20:52

    Content type: Case report

    Published on:

  19. Lung cancer surgery is associated with a high incidence of postoperative pulmonary complications (PPCs). Preliminary evidence suggests that ERAS processes can reduce overall incidence of PPCs as short- and lon...

    Authors: Yu Zheng, Mao Mao, Meifang Ji, Qiugang Zheng, Liang Liu, Zhigang Zhao, Haiming Wang, Xiangyang Wei, Yulong Wang, Jiamin Chen, Huiqing Zhou, Qiaoqiao Liang, Ying Chen, Xintong Zhang, Lu Wang, Yihui Cheng…

    Citation: BMC Pulmonary Medicine 2020 20:44

    Content type: Study protocol

    Published on:

  20. Cystic airspace is an uncommon imaging manifestation involved in non-small lung cancer (NSCLC). Diffuse cystic lesion is even rarer as pulmonary manifestation of NSCLC. In the present study, we reported a rare...

    Authors: Xianhua Gui, Jingjing Ding, Yan Li, Min Yu, Tingting Chen, Mei Huang and Yonglong Xiao

    Citation: BMC Pulmonary Medicine 2020 20:30

    Content type: Case report

    Published on:

  21. Lung cancer is the leading cause of cancer mortality in Australia. Guidelines suggest that patients with suspected lung cancer on thoracic imaging be referred for urgent specialist review. However, the term “s...

    Authors: P. Brownell, F. Piccolo, F. Brims, R. Norman and D. Manners

    Citation: BMC Pulmonary Medicine 2020 20:24

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Pulmonary Medicine 2020 20:53

  22. Due to the acquired drug resistance, the potency of cisplatin-based chemotherapy is limited in lung cancer, which is a big obstacle in clinical treatment of lung cancer. Abundant evidence has revealed that cir...

    Authors: Zhihui Wu, Qiang Gong, Yan Yu, Jialin Zhu and Wencan Li

    Citation: BMC Pulmonary Medicine 2020 20:10

    Content type: Research article

    Published on:

  23. Our study aimed to verify the prognostic value of circulating tumor cells (CTCs) prior to initial treatment on survival of non-small cell lung cancer (NSCLC) by using meta-analysis and system review of publish...

    Authors: Sha-Sha Jiang, Bo Deng, Yong-Geng Feng, Kai Qian, Qun-You Tan and Ru-Wen Wang

    Citation: BMC Pulmonary Medicine 2019 19:262

    Content type: Research article

    Published on:

  24. Lung adenocarcinoma associated transcript 1 (LUADT1) has been reported as an oncogenic long non-coding RNA (lncRNA) in lung adenocarcinoma, while its roles in small cell lung cancer (SCLC) are unknown. Our RNA...

    Authors: Dingxue Wang, Wenyu Wu, Wenqi Huang, Jinghui Wang, Li Luo and Dongxin Tang

    Citation: BMC Pulmonary Medicine 2019 19:246

    Content type: Research article

    Published on:

  25. The Robotic Endoscopic System (Auris Health, Inc., Redwood City, CA) has the potential to overcome several limitations of contemporary guided-bronchoscopic technologies for the diagnosis of lung lesions. Our o...

    Authors: Udit Chaddha, Stephen P. Kovacs, Christopher Manley, D. Kyle Hogarth, Gustavo Cumbo-Nacheli, Sivasubramanium V. Bhavani, Rohit Kumar, Manisha Shende, John P. Egan III and Septimiu Murgu

    Citation: BMC Pulmonary Medicine 2019 19:243

    Content type: Research article

    Published on:

  26. Recurrent pleural effusion is a common cause of dyspnoea, cough and chest pain during the course of malignant diseases. Chemical pleurodesis had been the only definitive treatment option until two decades ago....

    Authors: Nikolaj Frost, Martin Brünger, Christoph Ruwwe-Glösenkamp, Matthias Raspe, Antje Tessmer, Bettina Temmesfeld-Wollbrück, Dirk Schürmann, Norbert Suttorp and Martin Witzenrath

    Citation: BMC Pulmonary Medicine 2019 19:232

    Content type: Research article

    Published on:

  27. Flexible bronchoscopy enables visualization of the respiratory airway mucosa from the oropharynx to third generation branching of the tracheobronchial tree. Bronchoscopic diagnoses vary from one locality to th...

    Authors: Deus A. Ndilanha, Grace A. Shayo, Ramadhan Hassan, Moses Byomuganyizi and Leonard E. K. Lema

    Citation: BMC Pulmonary Medicine 2019 19:214

    Content type: Research article

    Published on:

  28. Spontaneous remission (SR) of cancer is a very rare phenomenon of unknown mechanism. In particular, SR of non-small cell lung cancer (NSCLC) has been scarcely reported. We present the case of a 74-year-old wom...

    Authors: Hee-Young Yoon, Heae Surng Park, Min Sun Cho, Sung Shin Shim, Yookyung Kim and Jin Hwa Lee

    Citation: BMC Pulmonary Medicine 2019 19:210

    Content type: Case report

    Published on:

  29. Lung cancer is one of the most incident neoplastic diseases, and a leading cause of death for cancer worldwide. Knowledge of the incidence of druggable genetic alterations, their correlation with clinical and ...

    Authors: Maria Colombino, Panagiotis Paliogiannis, Antonio Cossu, Davide Adriano Santeufemia, Maria Cristina Sini, Milena Casula, Grazia Palomba, Antonella Manca, Marina Pisano, Valentina Doneddu and Giuseppe Palmieri

    Citation: BMC Pulmonary Medicine 2019 19:209

    Content type: Research article

    Published on:

  30. The critical management of advanced non-small-cell lung carcinoma (NSCLC), especially when complicated by severe airway stenosis, is difficult and often leads to high clinical risks and medical costs.

    Authors: Ai-Gui Jiang, Hui-Yu Lu and Zhong-Qi Ding

    Citation: BMC Pulmonary Medicine 2019 19:205

    Content type: Case report

    Published on:

  31. Dose intensity and dose density of first line Platinum and Etoposide (PE) do not influence Overall Survival (OS) of Small Cell Lung Cancer (SCLC) patients. The effect of treatment length, however, remains uncl...

    Authors: Mostafa Sallam, Helen Wong and Carles Escriu

    Citation: BMC Pulmonary Medicine 2019 19:195

    Content type: Research article

    Published on:

  32. Radial endobronchial ultrasound (R-EBUS)-guided transbronchial biopsy (TBB) is a common diagnostic modality for peripheral pulmonary lesions; however, there is uncertainty about the optimal sequence of TBB and...

    Authors: Chun-Ta Huang, Yi-Ju Tsai, Chao-Chi Ho and Chong-Jen Yu

    Citation: BMC Pulmonary Medicine 2019 19:193

    Content type: Research article

    Published on:

  33. In non-small cell lung cancer (NSCLC) patients, concomitant idiopathic pulmonary fibrosis (IPF) and emphysema (CPFE) are independently related to poor survival. CPFE is a condition with features of both pulmon...

    Authors: Sung Woo Moon, Moo Suk Park, Young Sam Kim, Joon Jang, Jae Ho Lee, Choon-Taek Lee, Jin-Haeng Chung, Hyo Sup Shim, Kyung Won Lee, Seung-Seob Kim, Sang Hoon Lee and Ho Il Yoon

    Citation: BMC Pulmonary Medicine 2019 19:177

    Content type: Research article

    Published on:

  34. Emphysema and chronic obstructive pulmonary disease (COPD) are well known independent risk factors for lung cancer. However, the developmental mechanisms between emphysema/COPD and lung cancer remain unknown. ...

    Authors: Ken Arimura, Yasuo Sekine, Kenzo Hiroshima, Satoru Shimizu, Noriyuki Shibata, Mitsuko Kondo, Kiyoshi Takeyama and Etsuko Tagaya

    Citation: BMC Pulmonary Medicine 2019 19:169

    Content type: Research article

    Published on:

  35. The diagnosis of lung typical carcinoid tumors results challenging when limited size and unfavorable sampling location is associated. It has been reported that bronchoscopy with endobronchial ultrasound (EBUS)...

    Authors: Roberto Piro, Roberto Tonelli, Sofia Taddei, Alessandro Marchioni, Giovanni Musci, Enrico Clini and Nicola Facciolongo

    Citation: BMC Pulmonary Medicine 2019 19:168

    Content type: Case report

    Published on:

  36. Endobronchial ultrasound-guided trans-bronchial needle aspiration (EBUS-TBNA) is minimally invasive technique used for diagnosis and/or staging of benign and malignant pulmonary and non-pulmonary disease. Prev...

    Authors: Nicola Bailey, Zoe Krisnadi, Raena Kaur, Siobhain Mulrennan, Martin Phillips and Neli Slavova-Azmanova

    Citation: BMC Pulmonary Medicine 2019 19:155

    Content type: Research article

    Published on:

  37. The effectiveness of Incentive spirometry (IS) in patients undergoing video-assisted thoracic surgery (VATS) remains lacking. We conducted a population-based study to investigate the effectiveness of IS on pat...

    Authors: Chin-Jung Liu, Wen-Chen Tsai, Chia-Chen Chu, Chih-Hsin Muo and Wei-Sheng Chung

    Citation: BMC Pulmonary Medicine 2019 19:121

    Content type: Research article

    Published on:

  38. Malignant endobronchial mass (MEM) has poor prognosis, cryotherapy is reportedly to diagnose MEM, however, the therapeutic role of cryotherapy impacts on survival has not be well addressed.

    Authors: Fu-Tsai Chung, Chun-Liang Chou, Yu-Lun Lo, Chih-Hsi Kuo, Tsai-Yu Wang, Chun-Hwa Wang, Hung-Yu Huang, Horng-Chyuan Lin, Chih-Hao Chang, Chung-Shu Lee, Hao-Cheng Chen and Shu-Min Lin

    Citation: BMC Pulmonary Medicine 2019 19:101

    Content type: Research article

    Published on:

  39. Lobectomy is the standard treatment for patients with stage I non-small cell lung cancer (NSCLC). Recent studies have shown promising results of stereotactic body radiation therapy (SBRT) in these patients. We...

    Authors: Qingren Lin, Xiaojiang Sun, Ning Zhou, Zhun Wang, Yaping Xu and Yuezhen Wang

    Citation: BMC Pulmonary Medicine 2019 19:98

    Content type: Research article

    Published on:

  40. The presence of emphysema on computed tomography (CT) is associated with an increased frequency of lung cancer, but the postoperative outcomes of patients with pulmonary emphysema are not well known. The objec...

    Authors: Seijiro Sato, Masaya Nakamura, Yuki Shimizu, Tatsuya Goto, Terumoto Koike, Hiroyuki Ishikawa and Masanori Tsuchida

    Citation: BMC Pulmonary Medicine 2019 19:73

    Content type: Research article

    Published on:

  41. Acute exacerbation of interstitial lung disease (AE-ILD) is the most serious complication in lung cancer patients with pre-existing ILD receiving chemotherapy. The role of vascular endothelial growth factor (V...

    Authors: Shohei Hamada, Hidenori Ichiyasu, Tokunori Ikeda, Megumi Inaba, Kosuke Kashiwabara, Tomoki Sadamatsu, Nahoko Sato, Kimitaka Akaike, Hiroko Okabayashi, Koichi Saruwatari, Yusuke Tomita, Sho Saeki, Naomi Hirata, Takeshi Yoshinaga and Kazuhiko Fujii

    Citation: BMC Pulmonary Medicine 2019 19:72

    Content type: Research article

    Published on: