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BMC Pulmonary Medicine


Section edited by Montserrat Sanchez Cespedes

This section concerns all aspects of lung cancer including, but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Content type: Research article

    Radial-probe endobronchial ultrasound (rEBUS)-guided transbronchial biopsy (TBB) is invaluable in the diagnosis of peripheral pulmonary lesions (PPLs); however, in certain instances, the procedure has to be re...

    Authors: Chun-Ta Huang, Yi-Ju Tsai, Chao-Chi Ho and Chong-Jen Yu

    Citation: BMC Pulmonary Medicine 2017 17:132

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  2. Content type: Research article

    Lung cancer has been the leading cause of cancer-related mortality worldwide among both men and women in recent years. There is an increase in the incidence of nonsmoking-related lung cancer in recent years. T...

    Authors: Kuei-Feng Lin, Hsiu-Fu Wu, Wei-Chun Huang, Pei-Ling Tang, Ming-Ting Wu and Fu-Zong Wu

    Citation: BMC Pulmonary Medicine 2017 17:120

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  3. Content type: Research article

    This retrospective study investigated the association between the Charlson comorbidity index (CCI) score and the survival of patients with stage IIIB-IV (advanced, non-resectable) non-small cell lung cancer (N...

    Authors: Lei Zhao, Lai-Han Leung, Jing Wang, Huihui Li, Juanjuan Che, Lian Liu, Xiaojun Yao and Bangwei Cao

    Citation: BMC Pulmonary Medicine 2017 17:112

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  4. Content type: Research article

    Decorin is one of the most abundant proteoglycans of the extracellular matrix and is mainly secreted and deposited in the interstitial matrix by fibroblasts where it plays an important role in collagen turnove...

    Authors: S.N. Kehlet, C.L. Bager, N. Willumsen, B. Dasgupta, C. Brodmerkel, M. Curran, S. Brix, D.J. Leeming and M. A. Karsdal

    Citation: BMC Pulmonary Medicine 2017 17:110

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  5. Content type: Research article

    Medical thoracoscopy has been shown to be an efficacious procedure in diagnosing unexplained exudative pleural effusions with excellent safety. This study aimed to assess the diagnostic significance of thoraco...

    Authors: Yan-Bing Wu, Li-Li Xu, Xiao-Juan Wang, Zhen Wang, Jun Zhang, Zhao-Hui Tong and Huan-Zhong Shi

    Citation: BMC Pulmonary Medicine 2017 17:109

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  6. Content type: Research article

    We analyzed the differences between maximum and peak computed tomography (CT) numbers (M-P), respectively representing the densities of the solid center and the main periphery of ground-glass nodules (GGNs), a...

    Authors: Mingzheng Peng, Gang Yu, Chengzhong Zhang, Cuidi Li and Jinwu Wang

    Citation: BMC Pulmonary Medicine 2017 17:93

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  7. Content type: Research article

    ALK-rearranged lung cancers exhibit specific pathologic and clinical features and are responsive to anti-ALK therapies. Therefore, the detection of ALK-rearrangement is fundamental for...

    Authors: Adriane F. Evangelista, Maicon F. Zanon, Adriana Cruvinel Carloni, Flávia E. de Paula, Mariana Andozia Morini, Maressa Ferreira-Neto, Iberê Cauduro Soares, Jose Elias Miziara, Pedro de Marchi, Cristovam Scapulatempo-Neto and Rui M. Reis

    Citation: BMC Pulmonary Medicine 2017 17:86

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  8. Content type: Research article

    Electromagnetic navigation bronchoscopy (ENB) is an image-guided, minimally invasive approach that uses a flexible catheter to access pulmonary lesions.

    Authors: Sandeep J. Khandhar, Mark R. Bowling, Javier Flandes, Thomas R. Gildea, Kristin L. Hood, William S. Krimsky, Douglas J. Minnich, Septimiu D. Murgu, Michael Pritchett, Eric M. Toloza, Momen M. Wahidi, Jennifer J. Wolvers and Erik E. Folch

    Citation: BMC Pulmonary Medicine 2017 17:59

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  9. Content type: Research article

    The present study sought to evaluate the usefulness of EBUS-TBNA in the diagnosis of locoregional recurrence of lung cancer in a cohort of lung cancer patients who were previously treated surgically, and descr...

    Authors: José Sanz-Santos, Pere Serra, Felipe Andreo, Mohamed Torky, Carmen Centeno, Teresa Morán, Enric Carcereny, Esther Fernández, Samuel García-Reina and Juan Ruiz-Manzano

    Citation: BMC Pulmonary Medicine 2017 17:46

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  10. Content type: Research article

    Cumulative sum (CUSUM) analysis can be used to continuously monitor the performance of an individual or process and detect deviations from a preset or standard level of achievement. However, no previous study ...

    Authors: Yasuhiro Norisue, Yasuharu Tokuda, Mayrol Juarez, Ryo Uchimido, Shigeki Fujitani and David A. Stoeckel

    Citation: BMC Pulmonary Medicine 2017 17:32

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  11. Content type: Research article

    Staging of mediastinal lymph nodes in non-small cell lung cancer (NSCLC) is mandatory. The maximum Standard Uptake Value (SUVmax) obtained using F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) i...

    Authors: M. Serra Fortuny, M. Gallego, Ll Berna, C. Montón, L. Vigil, M. J. Masdeu, A. Fernández-Villar, M. I. Botana, R. Cordovilla, R. García-Luján, E. Cases and E. Monsó

    Citation: BMC Pulmonary Medicine 2016 16:177

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  12. Content type: Technical advance

    Nowadays, small peripheral pulmonary lesions (PPLs) are frequently detected and the prognosis of lung cancer depends on the early diagnosis. Because of the high fee and requiring specialized training, many adv...

    Authors: Chaosheng Deng, Xiaoming Cao, Dawen Wu, Haibo Ding, Ruixiong You, Qunlin Chen, Linying Chen, Xin Zhang, Qiaoxian Zhang and Yongquan Wu

    Citation: BMC Pulmonary Medicine 2016 16:166

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  13. Content type: Research article

    The most efficient approach to diagnose malignant pleural effusions (MPEs) is still controversial and uncertain. This study aimed to evaluate the utility of a combined approach using ultrasound (US)-guided cut...

    Authors: Jinlin Wang, Xinghua Zhou, Xiaohong Xie, Qing Tang, Panxiao Shen and Yunxiang Zeng

    Citation: BMC Pulmonary Medicine 2016 16:155

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  14. Content type: Research article

    Limited studies have examined the association between lung cancer and bronchiectasis (BE). This study evaluated the regional association between BE and lung cancer by analyzing the lobar location of lung cance...

    Authors: Yeon Wook Kim, Chang-Hoon Lee, Kwang-Nam Jin, Jung-Kyu Lee, Eun Young Heo, Sung Soo Park, Hee Soon Chung and Deog Kyeom Kim

    Citation: BMC Pulmonary Medicine 2016 16:151

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  15. Content type: Research article

    Re-biopsy for resistant non-small cell lung cancer (NSCLC) after treatment with epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) is important for selection of better therapy, but there h...

    Authors: Takehiro Izumo, Yuji Matsumoto, Christine Chavez and Takaaki Tsuchida

    Citation: BMC Pulmonary Medicine 2016 16:106

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  16. Content type: Research article

    Since the first articles published for over 10 years ago, endobronchial ultrasound (EBUS) has gained a strong scientific backing and has been incorporated into routine medical practice in pulmonology and thora...

    Authors: João Pedro Steinhauser Motta, Axel Tobias Kempa, Alexandre Pinto Cardoso, Marcos Eduardo Paschoal, Ronir Raggio Luiz, José Roberto Lapa e Silva and Franz Stanzel

    Citation: BMC Pulmonary Medicine 2016 16:101

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  17. Content type: Research article

    The epidermal growth factor receptor (EGFR) mutation status assessment has become increasingly important given the significant impact of tyrosine kinase inhibitors in lung cancer management.

    Authors: Andrei-Tudor Cernomaz, Ina Iuliana Macovei, Ionut Pavel, Carmen Grigoriu, Mihai Marinca, Florent Baty, Simona Peter, Radu Zonda, Martin Brutsche and Bogdan- Dragos Grigoriu

    Citation: BMC Pulmonary Medicine 2016 16:88

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  18. Content type: Research article

    Bronchoscopy is frequently used for the evaluation of suspicious pulmonary lesions found on computed tomography, but its sensitivity for detecting lung cancer is limited. Recently, a bronchial genomic classifi...

    Authors: J. Scott Ferguson, Ryan Van Wert, Yoonha Choi, Michael J. Rosenbluth, Kate Porta Smith, Jing Huang and Avrum Spira

    Citation: BMC Pulmonary Medicine 2016 16:66

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  19. Content type: Research article

    Radial endobronchial ultrasound with a guide sheath (EBUS-GS) has improved the diagnostic outcomes of peripheral lung lesions. However, to our knowledge, reports on the use of EBUS-GS for diagnosis of cavitary...

    Authors: Manabu Hayama, Norio Okamoto, Hidekazu Suzuki, Motohiro Tamiya, Takayuki Shiroyama, Ayako Tanaka, Takuji Nishida, Takashi Nishihara, Nobuko Uehara, Naoko Morishita, Kunimitsu Kawahara and Tomonori Hirashima

    Citation: BMC Pulmonary Medicine 2016 16:76

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  20. Content type: Research article

    The evaluation of solitary pulmonary lesions (SPL) requires a balance between procedure-related morbidity and diagnostic yield, particularly in areas where tuberculosis (TB) is endemic. Data on ultrathin bronc...

    Authors: Daniel Franzen, Andreas H. Diacon, Lutz Freitag, Pawel T. Schubert, Colleen A. Wright and Macé M. Schuurmans

    Citation: BMC Pulmonary Medicine 2016 16:62

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