COPD and occupational lung disease

Section edited by Craig Hersh

This section concerns all aspects of COPD, occupational lung disease, and smoking-related disorders including, but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Study protocol

    Effect of counselling during pulmonary rehabilitation on self-determined motivation towards physical activity in people with chronic obstructive pulmonary disease – protocol of a mixed methods study

    Physical activity promotion in people with Chronic Obstructive Pulmonary Disease (COPD) is focus of research and public health. Patient-centred interventions like counselling are promising approaches to help p...

    Anne-Kathrin Rausch-Osthoff, Nicola Greco, Ariane Schwank, Swantje Beyer, David Gisi, Mandy Scheermesser, André Meichtry, Noriane Sievi, Thomas Hess and Markus Wirz

    BMC Pulmonary Medicine 2017 17:115

    Published on: 17 August 2017

  2. Study protocol

    A multi-center randomized, controlled, open-label trial evaluating the effects of eosinophil-guided corticosteroid-sparing therapy in hospitalised patients with COPD exacerbations – The CORTICO steroid reduction in COPD (CORTICO-COP) study protocol

    The most commonly applied treatment for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is a 5-day course of high-dose systemic corticosteroids. However, this treatment has not been shown...

    Pradeesh Sivapalan, Mia Moberg, Josefin Eklöf, Julie Janner, Jørgen Vestbo, Rasmus Rude Laub, Andrea Browatzki, Karin Armbruster, Jon Torgny Wilcke, Niels Seersholm, Ulla Møller Weinreich, Ingrid Louise Titlestad, Helle Frost Andreassen, Charlotte Suppli Ulrik, Uffe Bødtger, Thyge Lynghøj Nielsen…

    BMC Pulmonary Medicine 2017 17:114

    Published on: 15 August 2017

  3. Research article

    White matter lesions characterise brain involvement in moderate to severe chronic obstructive pulmonary disease, but cerebral atrophy does not

    Brain pathology is relatively unexplored in chronic obstructive pulmonary disease (COPD). This study is a comprehensive investigation of grey matter (GM) and white matter (WM) changes and how these relate to d...

    Catherine A. Spilling, Paul W. Jones, James W. Dodd and Thomas R. Barrick

    BMC Pulmonary Medicine 2017 17:92

    Published on: 19 June 2017

  4. Study protocol

    Health coaching to improve self-management and quality of life for low income patients with chronic obstructive pulmonary disease (COPD): protocol for a randomized controlled trial

    Chronic obstructive pulmonary disease (COPD) severely hinders quality of life for those affected and is costly to the health care system. Care gaps in areas such as pharmacotherapy, inhaler technique, and know...

    Beatrice Huang, Rachel Willard-Grace, Denise De Vore, Jessica Wolf, Chris Chirinos, Stephanie Tsao, Danielle Hessler, George Su and David H. Thom

    BMC Pulmonary Medicine 2017 17:90

    Published on: 9 June 2017

  5. Research article

    Seasonal influenza vaccination in patients with COPD: a systematic literature review

    Influenza is a frequent cause of exacerbations of chronic obstructive pulmonary disease (COPD). Exacerbations are associated with worsening of the airflow obstruction, hospitalisation, reduced quality of life,...

    Rafik Bekkat-Berkani, Tom Wilkinson, Philippe Buchy, Gael Dos Santos, Dimitris Stefanidis, Jeanne-Marie Devaster and Nadia Meyer

    BMC Pulmonary Medicine 2017 17:79

    Published on: 3 May 2017

  6. Research article

    Asthma–COPD overlap syndrome (ACOS) in primary care of four Latin America countries: the PUMA study

    Asthma–COPD overlap syndrome (ACOS) prevalence varies depending on the studied population and definition criteria. The prevalence and clinical characteristics of ACOS in an at-risk COPD primary care population...

    Maria Montes de Oca, Maria Victorina Lopez Varela, Maria E. Laucho-Contreras, Alejandro Casas, Eduardo Schiavi and Juan Carlos Mora

    BMC Pulmonary Medicine 2017 17:69

    Published on: 21 April 2017

  7. Research article

    The utility of electron microscopy in detecting asbestos fibers and particles in BALF in diffuse lung diseases

    In patients with diffuse lung diseases, differentiating occupational lung diseases from other diseases is clinically important. However, the value of assessing asbestos and particles in bronchoalveolar lavage ...

    Takashi Kido, Yasuo Morimoto, Kazuhiro Yatera, Hiroshi Ishimoto, Takaaki Ogoshi, Keishi Oda, Kei Yamasaki, Toshinori Kawanami, Shohei Shimajiri and Hiroshi Mukae

    BMC Pulmonary Medicine 2017 17:71

    Published on: 21 April 2017

  8. Research article

    Hemosiderin in sputum macrophages may predict infective exacerbations of chronic obstructive pulmonary disease: a retrospective observational study

    Infective exacerbations of COPD are common and are accompanied by neutrophilic bronchitis in sputum. Increased respiratory iron content has been associated with respiratory tract infection, though it is unclea...

    Sindu Mohan, Terence Ho, Melanie Kjarsgaard, Katherine Radford, A. S. M. Borhan, Lehana Thabane and Parameswaran Nair

    BMC Pulmonary Medicine 2017 17:60

    Published on: 12 April 2017

  9. Research article

    Characteristics and longitudinal progression of chronic obstructive pulmonary disease in GOLD B patients

    The characteristics and natural history of GOLD B COPD patients are not well described. The clinical characteristics and natural history of GOLD B patients over 1 year in a multicentre cohort of COPD patients ...

    Philip J. Lawrence, Umme Kolsum, Vandana Gupta, Gavin Donaldson, Richa Singh, Bethan Barker, Leena George, Adam Webb, Anthony J. Brookes, Christopher Brightling, Jadwiga Wedzicha and Dave Singh

    BMC Pulmonary Medicine 2017 17:42

    Published on: 20 February 2017

  10. Research article

    Cooking smoke and respiratory symptoms of restaurant workers in Thailand

    Restaurant workers are at risk from exposure to toxic compounds from burning of fuel and fumes from cooking. However, the literature is almost silent on the issue. What discussion that can be found in the lite...

    Chudchawal Juntarawijit and Yuwayong Juntarawijit

    BMC Pulmonary Medicine 2017 17:41

    Published on: 17 February 2017

  11. Study protocol

    Early detection of COPD patients in GOLD 0 population: an observational non-interventional cohort study - MARKO study

    Main risk factor for the development of chronic obstructive pulmonary disease (COPD) is smoking, although only less than 1/3 of smokers develop clinically manifest COPD. COPD’s progressive nature with high dis...

    Žarko Vrbica, Marina Labor, Ivan Gudelj, Slavica Labor, Iva Jurić and Davor Plavec

    BMC Pulmonary Medicine 2017 17:36

    Published on: 10 February 2017

  12. Research article

    Airway wall thickness on HRCT scans decreases with age and increases with smoking

    To investigate if age, gender and smoking are associated with airway wall thickness (AWT) measured by high resolution computed tomography (HRCT) and if higher AWT is associated with lower levels of pulmonary f...

    Eef D. Telenga, Matthijs Oudkerk, Peter M. A. van Ooijen, Rozemarijn Vliegenthart, Nick H. T. ten Hacken, Dirkje S. Postma and Maarten van den Berge

    BMC Pulmonary Medicine 2017 17:27

    Published on: 1 February 2017

  13. Research article

    Immediate salbutamol responsiveness does not predict long-term benefits of indacaterol in patients with chronic obstructive pulmonary disease

    The purpose of this study was to evaluate the correlation between immediate responsiveness with the short-acting β2-agonist salbutamol and effects of treatment with the ultra-long-acting β2-agonist indacaterol in...

    Pierre-Régis Burgel, Vincent Le Gros, Laurent Decuypère, Isabelle Bourdeix, Thierry Perez and Gaëtan Deslée

    BMC Pulmonary Medicine 2017 17:25

    Published on: 31 January 2017

  14. Study protocol

    Effects of periodontal treatment on exacerbation frequency and lung function in patients with chronic periodontitis: study protocol of a 1-year randomized controlled trial

    Chronic obstructive pulmonary disease (COPD) has been associated with periodontal disease (PD), and periodontal treatment (PT) has been connected to reduction of lung disease exacerbations. Bronchiectasis has ...

    Sergio Romero Santos, Erika Horácio Pinto, Priscila Larcher Longo, Simone Dal Corso, Fernanda Cordoba Lanza, Rafael Stelmach, Samia Zahi Rached, Adriana Lino-dos-Santos-Franco, Marcia Pinto Alves Mayer, Sandra Kalil Bussadori, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari and Anna Carolina Ratto Tempestini Horliana

    BMC Pulmonary Medicine 2017 17:23

    Published on: 23 January 2017

    The Erratum to this article has been published in BMC Pulmonary Medicine 2017 17:51

  15. Study protocol

    Multi-center, randomized, placebo-controlled trial of nocturnal oxygen therapy in chronic obstructive pulmonary disease: a study protocol for the INOX trial

    Long-term oxygen therapy (LTOT) is the only component of the management of chronic obstructive pulmonary disease (COPD) that improves survival in patients with severe daytime hypoxemia. LTOT is usually provide...

    Yves Lacasse, Sarah Bernard, Frédéric Sériès, Van Hung Nguyen, Jean Bourbeau, Shawn Aaron and François Maltais

    BMC Pulmonary Medicine 2017 17:8

    Published on: 9 January 2017

  16. Research article

    Prevalence of airflow obstruction in patients with stable systolic heart failure

    Chronic obstructive pulmonary disease (COPD) is an important differential diagnosis in heart failure (HF). However, routine use of spirometry in outpatient HF clinics is not implemented. The aim of the present...

    Morten Dalsgaard, Louis Lind Plesner, Morten Schou, Erik Kjøller, Jørgen Vestbo and Kasper Iversen

    BMC Pulmonary Medicine 2017 17:6

    Published on: 6 January 2017

  17. Research article

    Symptom profiles and inflammatory markers in moderate to severe COPD

    Physical and psychological symptoms are the hallmark of patients’ subjective perception of their illness. The purpose of this analysis was to determine if patients with COPD have distinctive symptom profiles a...

    Huong Q. Nguyen, Jerald R. Herting, Kenneth C. Pike, Sina A. Gharib, Gustavo Matute-Bello, Soo Borson, Ruth Kohen, Sandra G. Adams and Vincent S. Fan

    BMC Pulmonary Medicine 2016 16:173

    Published on: 3 December 2016

  18. Research article

    Clinical, physiologic, and radiographic factors contributing to development of hypoxemia in moderate to severe COPD: a cohort study

    Hypoxemia is a major complication of COPD and is a strong predictor of mortality. We previously identified independent risk factors for the presence of resting hypoxemia in the COPDGene cohort. However, little...

    J. Michael Wells, Raul San Jose Estepar, Merry-Lynn N. McDonald, Surya P. Bhatt, Alejandro A. Diaz, William C. Bailey, Francine L. Jacobson, Mark T. Dransfield, George R. Washko, Barry J. Make, Richard Casaburi, Edwin J. R. van Beek, Eric A. Hoffman, Frank C. Sciurba, James D. Crapo, Edwin K. Silverman…

    BMC Pulmonary Medicine 2016 16:169

    Published on: 1 December 2016

  19. Research article

    The prognostic value of measurement of high-sensitive cardiac troponin T for mortality in a cohort of stable chronic obstructive pulmonary disease patients

    Cardiovascular disease (CVD) is a common comorbidity in chronic obstructive pulmonary disease (COPD). Cardiac troponin (cTn) elevation, indicating myocardial injury, is frequent during acute COPD exacerbations...

    Anke Neukamm, Gunnar Einvik, Arne Didrik Høiseth, Vidar Søyseth, Nils Henrik Holmedahl, Natalia Kononova and Torbjørn Omland

    BMC Pulmonary Medicine 2016 16:164

    Published on: 25 November 2016

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