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Epidemiology and public health

This section concerns all aspects of the epidemiology of pulmonary disorders including but not limited to: cohort studies, genetic association studies, and prevalence studies.

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  1. Lower respiratory tract infection (LRIs) is very common both in terms of community-acquired infection and hospital-acquired infection. Sputum and bronchoalveolar lavage fluid (BALF) are the most important spec...

    Authors: Zheng Peng, Jin’an Zhou and Lei Tian

    Citation: BMC Pulmonary Medicine 2020 20:233

    Content type: Research article

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  2. It has been shown that home mechanical ventilation improves quality of life, but it has not been widely studied which particular patient groups benefit the most from starting this type of therapy. The purpose ...

    Authors: Luca Valko, Szabolcs Baglyas, V. Anna Gyarmathy, Janos Gal and Andras Lorx

    Citation: BMC Pulmonary Medicine 2020 20:221

    Content type: Research article

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  3. Tumor necrosis factor-α (TNF-α) has been reported to play a part in the development of obstructive sleep apnea (OSA) and its complications. However, the relationship between TNF-α and OSA still remains inconcl...

    Authors: Yuan Cao, Yali Song, Pu Ning, Liyu Zhang, Shuang Wu, Juan Quan and Qiao Li

    Citation: BMC Pulmonary Medicine 2020 20:215

    Content type: Review

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  4. Asthma is one of the leading causes of disease burden when measured in terms of disability adjusted life years, despite low prevalence of self-reported cases among young women. This paper deals with the meso-s...

    Authors: Shri Kant Singh, Jitendra Gupta, Himani Sharma, Sarang P. Pedgaonkar and Nidhi Gupta

    Citation: BMC Pulmonary Medicine 2020 20:190

    Content type: Research article

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  5. The six-minute walking test (6MWT) is a tool that plays a key role in evaluating the functional exercise capacity, prognosis and evaluation of treatment response of patients with various cardiopulmonary diseas...

    Authors: He Zou, Jia Zhang, Yingying Zou, Xiaoshu Chen, Yi Wang, Hao Chen, Fanhao Ye and Haizhu Yu

    Citation: BMC Pulmonary Medicine 2020 20:177

    Content type: Research article

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  6. Beginning at a young age, children with cystic fibrosis (CF) embark on demanding care regimens that pose challenges to parents. We examined the extent to which clinical, demographic and psychosocial features i...

    Authors: Rhonda D. Szczesniak, Teresa Pestian, Leo L. Duan, Dan Li, Sophia Stamper, Brycen Ferrara, Elizabeth Kramer, John P. Clancy and Daniel Grossoehme

    Citation: BMC Pulmonary Medicine 2020 20:174

    Content type: Research article

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  7. The prevalence of non-cystic fibrosis (CF) bronchiectasis is increasing in both developed and developing countries in recent years. Although the main features remain similar, etiologies seem to change. Our aim...

    Authors: Ela Erdem Eralp, Yasemin Gokdemir, Emine Atag, Nilay Bas Ikizoglu, Pinar Ergenekon, Cansu Yilmaz Yegit, Arif Kut, Refika Ersu, Fazilet Karakoc and Bulent Karadag

    Citation: BMC Pulmonary Medicine 2020 20:172

    Content type: Research article

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  8. Low lung function has been associated with increased body mass index (BMI). The aim of this study was to investigate whether the effect of BMI on lung function is mediated by DNA methylation.

    Authors: André F. S. Amaral, Medea Imboden, Matthias Wielscher, Faisal I. Rezwan, Cosetta Minelli, Judith Garcia-Aymerich, Gabriela P. Peralta, Juha Auvinen, Ayoung Jeong, Emmanuel Schaffner, Anna Beckmeyer-Borowko, John W. Holloway, Marjo-Riitta Jarvelin, Nicole M. Probst-Hensch and Deborah L. Jarvis

    Citation: BMC Pulmonary Medicine 2020 20:171

    Content type: Research article

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  9. Supervised cardio-pulmonary rehabilitation may be safe and beneficial for people with pulmonary hypertension (PH) in groups 1 (pulmonary arterial hypertension) and 4 (chronic thromboembolic disease), particula...

    Authors: Gordon McGregor, Julie Bruce, Stuart Ennis, James Mason, Ranjit Lall, Chen Ji, Harbinder Sandhu, Kate Seers, Prithwish Banerjee, Alastair Canaway, Katie Booth, Stephanie J. C. Taylor, Elizabeth Robertson, Tamar Pincus, Sally Singh, David Fitzmaurice…

    Citation: BMC Pulmonary Medicine 2020 20:143

    Content type: Study protocol

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  10. Attenuated decreases in lung function can signal the onset of acute respiratory events known as pulmonary exacerbations (PEs) in children and adolescents with cystic fibrosis (CF). Univariate joint modeling fa...

    Authors: E. R. Andrinopoulou, J. P. Clancy and R. D. Szczesniak

    Citation: BMC Pulmonary Medicine 2020 20:142

    Content type: Research article

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  11. Home mechanical ventilation is a reliable treatment for patients suffering from chronic respiratory failure, improving survival and quality of life. Prevalence has been increasing worldwide as a result of evol...

    Authors: Luca Valko, Szabolcs Baglyas, Laszlo Kunos, Attila Terray-Horvath, Andras Lorx, Janos Gal and Wolfram Windisch

    Citation: BMC Pulmonary Medicine 2020 20:130

    Content type: Research article

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  12. Electronic cigarettes/e-cigarettes (ECs), or vaping, is currently the most popular form of smoking amongst youth in the United States. ECs are battery-powered devices that vaporize a liquid that comes in small...

    Authors: Andrew L. Silverman, Haseeb Siddique, Vikas Kumar, Thuy-Hong Le and Joseph Ng

    Citation: BMC Pulmonary Medicine 2020 20:118

    Content type: Research article

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  13. Handgrip strength (HGS) has been widely studied in clinical and epidemiological settings, but the relationship between HGS and pulmonary function is still controversial. This study analysed pulmonary function ...

    Authors: Liangmei Chen, Xiaomin Liu, Qian Wang, Linpei Jia, Kangkang Song, Sasa Nie, Yinping Zhang, Dan Cao, Delong Zhao, Zuoxiang Li, Zheyi Dong, Ying Zheng, Shuwei Duan, Xuefeng Sun, Zhe Feng, Guangyan Cai…

    Citation: BMC Pulmonary Medicine 2020 20:114

    Content type: Research article

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  14. The epidemiology of acute kidney injury (AKI) in nonexacerbated chronic obstructive pulmonary disease (NECOPD) patients is unknown. This study investigated the factors associated with AKI and the association b...

    Authors: Xiaohong Wang, Zhen Xie, Shuguang Xiong, Wei Xiong, Tian Zhong and Yang Su

    Citation: BMC Pulmonary Medicine 2020 20:108

    Content type: Research article

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  15. WHO’s directly observed therapy (DOT) strategy for tuberculosis (TB) treatment depends upon a well–organized healthcare system. This study sought to evaluate the effectiveness of self-administered drug intake ...

    Authors: Vahe Khachadourian, Nune Truzyan, Arusyak Harutyunyan, Varduhi Petrosyan, Hayk Davtyan, Karapet Davtyan, Martin van den Boom and Michael E. Thompson

    Citation: BMC Pulmonary Medicine 2020 20:105

    Content type: Research article

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  16. Factors associated with reduced daily physical activity (DPA) in patients with COPD are still controversial. Physical inactivity in COPD increases risk of cardiovascular disease, frequent exacerbations, reduce...

    Authors: Ali M. Albarrati, Nichola S. Gale, Maggie M. Munnery, John R. Cockcroft and Dennis J. Shale

    Citation: BMC Pulmonary Medicine 2020 20:60

    Content type: Research article

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  17. The 2012 Global Lung Function Initiative (GLI2012) provide multi-ethnic spirometric reference equations (SRE) for the 3–95 year-old age range, but Sub-Saharan African populations are not represented. This study a...

    Authors: Tafadzwa Madanhire, Rashida A. Ferrand, Engi F. Attia, Elopy N. Sibanda, Simba Rusakaniko and Andrea M. Rehman

    Citation: BMC Pulmonary Medicine 2020 20:56

    Content type: Research article

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  18. There is low diagnostic accuracy of the proxy restrictive spirometric pattern (RSP) to identify true pulmonary restriction. This knowledge is based on patients referred for spirometry and total lung volume det...

    Authors: Kjell Torén, Linus Schiöler, Jonas Brisman, Andrei Malinovschi, Anna-Carin Olin, Göran Bergström and Björn Bake

    Citation: BMC Pulmonary Medicine 2020 20:55

    Content type: Research article

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  19. Bronchiectasis is a chronic infectious respiratory disease with diverse causes and ethnic or geographic differences. However, few large-scale studies of its etiology have been conducted in Asia. This study aim...

    Authors: Hung-Yu Huang, Fu-Tsai Chung, Chun-Yu Lo, Horng-Chyuan Lin, Yu-Tung Huang, Chih-Hsin Yeh, Chang-Wei Lin, Yu-Chen Huang and Chun-Hua Wang

    Citation: BMC Pulmonary Medicine 2020 20:45

    Content type: Database

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  20. Lung cancer is the most common cause of cancer related death worldwide and survival is poor. Patients with lung cancer may develop a critical illness, but it is unclear what features are associated with an Int...

    Authors: Kathryn Puxty, Christopher H. Grant, Philip McLoone, Billy Sloan, Tara Quasim, Kate Hulse and David S. Morrison

    Citation: BMC Pulmonary Medicine 2020 20:36

    Content type: Research article

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  21. The risk of injury directly related to hospitalization for motor vehicle accidents (MVAs) in the obstructive sleep apnea (OSA) patients has not been thoroughly understood. Our study aimed to examine the associ...

    Authors: Yi-Chang Lin, Tien-Yu Chen, Wu-Chien Chien, Chi-Hsiang Chung, Hsin-An Chang, Yu-Chen Kao, Chien-Sung Tsai, Chih-Sheng Lin and Nian-Shen Tzeng

    Citation: BMC Pulmonary Medicine 2020 20:28

    Content type: Research article

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  22. Recent research has proposed an association between desaturation during a six minute walking test (6MWT) and osteoporosis in an elderly group of individuals with non-cystic fibrosis bronchiectasis. A causative...

    Authors: Owen W. Tomlinson and Dimitris Vlachopoulos

    Citation: BMC Pulmonary Medicine 2020 20:23

    Content type: Correspondence

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  23. Community-acquired pneumonia (CAP) is one of the leading causes of morbidity and mortality worldwide, often leading to hospital admissions. In Portugal, the factors associated with in-hospital mortality due to...

    Authors: Ezequiel Pessoa, Cristina Bárbara, Laura Viegas, Andreia Costa, Matilde Rosa and Paulo Nogueira

    Citation: BMC Pulmonary Medicine 2020 20:18

    Content type: Research article

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  24. This study aimed to determine the association between chronic periodontitis (CP) and community-acquired pneumonia (CAP) according to CP severity in the Korean population based on the National Health Insurance ...

    Authors: Seon-Jip Kim, Kyuwoong Kim, Seulggie Choi, Jooyoung Chang, Sung Min Kim, Sang Min Park and Hyun-Jae Cho

    Citation: BMC Pulmonary Medicine 2019 19:268

    Content type: Research article

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  25. Use of humidifier disinfectants (HD) at home leads to chemical airborne exposure, causing HD associated lung injury (HDLI) with high mortality. However, the lung function in children diagnosed with HDLI is not...

    Authors: Hyun-Ju Cho, So Yeon Lee, Donguk Park, Seung-Hun Ryu, Jisun Yoon, Sungsu Jung, Eun Lee, Song-I Yang and Soo-Jong Hong

    Citation: BMC Pulmonary Medicine 2019 19:261

    Content type: Research article

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  26. To promote the utilization of pulmonary function tests (PFT) through analyzing the data of PFT during the past seven years in one large teaching hospital in China.

    Authors: Fei Li, Zhi-wen Huang, Xiao-fei Wang, Hui-wen Xu, Hua Yu, Yan-bin Chen, Jian-an Huang, Jia-jia Wang and Wei Lei

    Citation: BMC Pulmonary Medicine 2019 19:259

    Content type: Research article

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  27. Pediatric community acquired pneumonia (pedCAP) is one of the leading causes for childhood morbidity accounting for up to 20% of pediatric hospital admissions in high income countries. In spite of its high mor...

    Authors: Martin Wetzke, Matthias Volkmar Kopp, Jürgen Seidenberg, Christian Vogelberg, Tobias Ankermann, Christine Happle, Gesche Voigt, Holger Köster, Thomas Illig, Christiane Lex, Antje Schuster, Marcus Panning, Grit Barten, Gernot Rohde, Tobias Welte and Gesine Hansen

    Citation: BMC Pulmonary Medicine 2019 19:238

    Content type: Study protocol

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  28. Globally, tuberculosis (TB) lasts a major public health concern. Using feasible strategies to estimate TB infectious periods is crucial. The aim of this study was to determine the magnitude of TB infectious pe...

    Authors: Mulusew Andualem Asemahagn, Getu Degu Alene and Solomon Abebe Yimer

    Citation: BMC Pulmonary Medicine 2019 19:229

    Content type: Research article

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  29. To quantify the financial cost of pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc).

    Authors: Kathleen Morrisroe, Wendy Stevens, Joanne Sahhar, Gene-Siew Ngian, Nava Ferdowsi, Dylan Hansen, Shreeya Patel, Catherine L. Hill, Janet Roddy, Jennifer Walker, Susanna Proudman and Mandana Nikpour

    Citation: BMC Pulmonary Medicine 2019 19:226

    Content type: Research article

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  30. Physical activity is recommended in the management of cystic fibrosis (CF). The aim of this study was to explore motives, barriers and enablers to physical activity among this population. Methods: Twelve parti...

    Authors: S. Denford, D. M. Hill, K. A. Mackintosh, M. A. McNarry, A. R. Barker and C. A. Williams

    Citation: BMC Pulmonary Medicine 2019 19:220

    Content type: Research article

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  31. Anti-tuberculosis therapy requires at least six-month treatment with continuous administration of combined antibiotics, including isoniazid, rifampicin, pyrazinamide, and ethambutol. The long-term exposure to ...

    Authors: Wenpei Shi, Yi Hu, Xubin Zheng, Zhu Ning, Meiying Wu, Fan Xia, Stefanie Prast-Nielsen, Yue O. O. Hu and Biao Xu

    Citation: BMC Pulmonary Medicine 2019 19:211

    Content type: Study protocol

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  32. IgG4-related disease (IgG4-RD) is a systemic autoimmune disease that can affect multiple organs of the body. Pulmonary manifestations of IgG4-RD include pulmonary solid nodules, thickening of bronchovascular b...

    Authors: Xiuling Wang, Jun Wan, Ling Zhao, Jiping Da, Bin Cao and Zhenguo Zhai

    Citation: BMC Pulmonary Medicine 2019 19:191

    Content type: Case report

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  33. Limited data exists regarding healthcare utilization, medical expenses, and prognosis of pulmonary hypertension (PH) according to the World Health Organization (WHO) classification. We aimed to investigate mor...

    Authors: In-Chang Hwang, Goo-Yeong Cho, Hong-Mi Choi, Yeonyee E. Yoon, Jin Joo Park, Jun-Bean Park, Seung-Pyo Lee, Hyung-Kwan Kim, Yong-Jin Kim and Dae-Won Sohn

    Citation: BMC Pulmonary Medicine 2019 19:189

    Content type: Research article

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  34. E-cigarette use prevalence has grown rapidly in the US. Despite the popularity of these products, few acute exposure toxicity studies exist, and studies on long-term pulmonary health effects are limited. E-cig...

    Authors: Albert D. Osei, Mohammadhassan Mirbolouk, Olusola A. Orimoloye, Omar Dzaye, S. M. Iftekhar Uddin, Zeina A. Dardari, Andrew P. DeFilippis, Aruni Bhatnagar and Michael J. Blaha

    Citation: BMC Pulmonary Medicine 2019 19:180

    Content type: Research article

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  35. Wheezes and crackles are well-known signs of lung diseases, but can also be heard in apparently healthy adults. However, their prevalence in a general population has been sparsely described. The objective of t...

    Authors: J. C. Aviles-Solis, C. Jácome, A. Davidsen, R. Einarsen, S. Vanbelle, H. Pasterkamp and H. Melbye

    Citation: BMC Pulmonary Medicine 2019 19:173

    Content type: Research article

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  36. Histoplasmosis is a mycosis caused by soil-based fungus Histoplasma capsulatum endemic in the USA, Latin America, Africa and South-East Asia. The disease is usually self-resolving, but exposure to a large inoculu...

    Authors: Krzysztof Specjalski, Karolina Kita, Krzysztof Kuziemski, Beata Tokarska, Lucyna Górska, Jolanta Szade, Alicja Siemińska, Marta Chełmińska and Ewa Jassem

    Citation: BMC Pulmonary Medicine 2019 19:150

    Content type: Case report

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  37. Pneumonia is a significant public health problem globally. The early identification and management of the determinants of pneumonia demands clear evidence. But, there is a limited data on this issue in the cur...

    Authors: Sefinew Getaneh, Girma Alem, Maru Meseret, Yihun Miskir, Tilahun Tewabe, Gebeyaw Molla and Yihalem Abebe Belay

    Citation: BMC Pulmonary Medicine 2019 19:147

    Content type: Research article

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  38. Epidemiologic characteristics of nontuberculous mycobacterial (NTM) disease remain largely unknown. The objective of this study was to evaluate incidence, prevalence, and mortality of NTM infection in a large ...

    Authors: Seon Cheol Park, Min Jin Kang, Chang Hoon Han, Sun Min Lee, Cheong Ju Kim, Jung Mo Lee and Young Ae Kang

    Citation: BMC Pulmonary Medicine 2019 19:140

    Content type: Research article

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  39. The Nelson mortality results were presented in September 2018. Four other randomized control trials (RCTs) were also reported the latest mortality outcomes in 2018 and 2019. We therefore conducted a meta-analy...

    Authors: Kai-Lin Huang, Shih-Yuan Wang, Wan-Chen Lu, Ya-Hui Chang, Jian Su and Yen-Ta Lu

    Citation: BMC Pulmonary Medicine 2019 19:126

    Content type: Research article

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    The Correspondence to this article has been published in BMC Pulmonary Medicine 2020 20:225

  40. Medical thoracoscopy is considered an overall safe procedure, whereas numbers of studies focus on complications of diagnostic thoracoscopy and talc poudrage pleurodesis. We conduct this study to evaluate the s...

    Authors: Yun-Yan Wan, Cong-Cong Zhai, Xin-Shan Lin, Zhou-Hong Yao, Qing-Hua Liu, Ling Zhu, De-Zhi Li, Xi-Li Li, Ning Wang and Dian-Jie Lin

    Citation: BMC Pulmonary Medicine 2019 19:125

    Content type: Research article

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  41. Pulmonary tuberculosis is a leading cause of morbidity and mortality in developing countries. Drug resistance, a huge problem in this contagious disease, is driven by point mutations in the Mycobacterium tubercul...

    Authors: David Patrick Kateete, Rogers Kamulegeya, Edgar Kigozi, Fred Ashaba Katabazi, Deus Lukoye, Sindani Ireneaus Sebit, Hergeye Abdi, Peter Arube, George William Kasule, Kenneth Musisi, Myalo Glen Dlamini, Derrick Khumalo and Moses L. Joloba

    Citation: BMC Pulmonary Medicine 2019 19:124

    Content type: Research article

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  42. With rising medical costs, stakeholders and healthcare professionals are exploring community-based solutions to relieve the burden of chronic diseases and reduce health care spending. The community health work...

    Authors: Trisha M. Parekh, Carla R. Copeland, Mark T. Dransfield and Andrea Cherrington

    Citation: BMC Pulmonary Medicine 2019 19:116

    Content type: Research article

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  43. Tuberculous pleurisy and malignancy are two of the most common causes of pleural effusion. IL-33 is expressed in the epithelial lining and endothelial cells and is released after cell damage; it is proposed to...

    Authors: Abdel-sadek Hamed Al-aarag, Mohammad Hussein Kamel, Eman Ramadan Abdelgawad, Shaimaa Magdy Abo-Youssef, Hany Hussein Moussa, Marwa Elsayed Elnaggar, Rasha Mohammad Hendy and Koot Ahmad Diab

    Citation: BMC Pulmonary Medicine 2019 19:114

    Content type: Research article

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  44. Epidemiological research on health effects of livestock exposure in population subgroups with compromised respiratory health is still limited. The present study explored the association between livestock expos...

    Authors: Christos Baliatsas, Lidwien A. M. Smit, Michel L. A. Dückers, Christel E. van Dijk, Dick Heederik and C. Joris Yzermans

    Citation: BMC Pulmonary Medicine 2019 19:105

    Content type: Research article

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  45. The prevalence of chronic obstructive pulmonary disease (COPD) in Anhui Province of eastern China remain uncertain. The present study provides the first estimate of the prevalence and risk factors of COPD in A...

    Authors: Zhenqiu Zha, Ruixue Leng, Wei Xu, Heling Bao, Yeji Chen, Liwen Fang, Zhirong Liu and Dongqing Ye

    Citation: BMC Pulmonary Medicine 2019 19:102

    Content type: Research article

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  46. The management and control of pulmonary bacteriologically confirmed (PBC) tuberculosis (TB) also known as infectious TB is important not only to monitor for resistance but also to check for severity, treatment...

    Authors: Nicholas Sebuliba Kirirabwa, Derrick Kimuli, Carol Nanziri, Denis Sama, Syrus Ntudhu, Daniel Ayen Okello, Raymond Byaruhanga, Deus Lukoye and Samuel Kasozi

    Citation: BMC Pulmonary Medicine 2019 19:91

    Content type: Research article

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  47. Social determinants may influence the incidence and control of tuberculosis (TB). The aim of this study was to evaluate the correlation between social determinants and pulmonary TB (PTB) incidence and treatmen...

    Authors: Alessandra Isabel Zille, Guilherme Loureiro Werneck, Ronir Raggio Luiz and Marcus Barreto Conde

    Citation: BMC Pulmonary Medicine 2019 19:87

    Content type: Research article

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  48. Differentiating bacterial from viral pneumonia is important for guiding targeted management and judicious use of antibiotics. We assessed if clinical characteristics and blood inflammatory biomarkers could be ...

    Authors: Mejbah U. Bhuiyan, Christopher C. Blyth, Rachel West, Jurissa Lang, Tasmina Rahman, Caitlyn Granland, Camilla de Gier, Meredith L. Borland, Ruth B. Thornton, Lea-Ann S. Kirkham, Andrew Martin, Peter C. Richmond, David W. Smith, Adam Jaffe and Thomas L. Snelling

    Citation: BMC Pulmonary Medicine 2019 19:71

    Content type: Research article

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  49. Relationships between low forced vital capacity (FVC), and morbidity have previously been studied but there are no data available for the Caribbean population. This study assessed the association of low FVC wi...

    Authors: Sateesh Sakhamuri, Fallon Lutchmansingh, Donald Simeon, Liane Conyette, Peter Burney and Terence Seemungal

    Citation: BMC Pulmonary Medicine 2019 19:62

    Content type: Research article

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