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Infectious, Rare and Idiopathic Pulmonary Diseases

Section edited by Sanjay Chotirmall and Giovanni Sotgiu

This section concerns all aspects of pulmonary infection, rare and idiopathic lung diseases including, but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Content type: Research article

    Mortality prediction of pneumonia by severity scores in patients with multiple underlying health conditions has not fully been investigated. This prospective cohort study is to identify mortality-associated un...

    Authors: Sugihiro Hamaguchi, Motoi Suzuki, Kota Sasaki, Masahiko Abe, Takao Wakabayashi, Eiichiro Sando, Makito Yaegashi, Shimpei Morimoto, Norichika Asoh, Naohisa Hamashige, Masahiro Aoshima, Koya Ariyoshi and Konosuke Morimoto

    Citation: BMC Pulmonary Medicine 2018 18:88

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  2. Content type: Research article

    Those affected by advanced fibrotic interstitial lung diseases have limited treatment options and in the terminal stages, the focus of care is on symptom management. However, quantitatively, little is known ab...

    Authors: Sabrina Carvajalino, Carla Reigada, Miriam J. Johnson, Mendwas Dzingina and Sabrina Bajwah

    Citation: BMC Pulmonary Medicine 2018 18:78

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  3. Content type: Research article

    Data on the lung microbiome in HIV-infected children is limited. The current study sought to determine the lung microbiome in HIV-associated bronchiectasis and to assess its association with pulmonary exacerba...

    Authors: Refiloe Masekela, Solize Vosloo, Stephanus N. Venter, Wilhelm Z. de Beer and Robin J. Green

    Citation: BMC Pulmonary Medicine 2018 18:87

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  4. Content type: Research article

    Bronchiectasis is a chronic respiratory condition. Persistent bacterial colonisation in the stable state with increased and sometimes altered bacterial burden during exacerbations are accepted as key features ...

    Authors: Alicia B. Mitchell, Bassel Mourad, Lachlan Buddle, Matthew J. Peters, Brian G. G. Oliver and Lucy C. Morgan

    Citation: BMC Pulmonary Medicine 2018 18:84

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  5. Content type: Review

    Bronchiectasis is an incurable lung disease characterised by irreversible airway dilatation. It causes symptoms including chronic productive cough, dyspnoea, and recurrent respiratory infections often requirin...

    Authors: Katy L. M. Hester, Julia Newton, Tim Rapley and Anthony De Soyza

    Citation: BMC Pulmonary Medicine 2018 18:80

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  6. Content type: Review

    Bronchiectasis is a common feature of severe inherited and acquired pulmonary disease conditions. Among inherited diseases, cystic fibrosis (CF) is the major disorder associated with bronchiectasis, while acqu...

    Authors: Jürgen Schäfer, Matthias Griese, Ravishankar Chandrasekaran, Sanjay H. Chotirmall and Dominik Hartl

    Citation: BMC Pulmonary Medicine 2018 18:79

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  7. Content type: Research article

    Bronchiectasis is a heterogeneous disease which affects quality of life. Measuring symptoms and quality of life has proved challenging and research is limited by extrapolation of questionnaires and treatments ...

    Authors: Emily K. Dudgeon, Megan Crichton and James D. Chalmers

    Citation: BMC Pulmonary Medicine 2018 18:81

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  8. Content type: Review

    Bronchiectasis is a disease associated with chronic progressive and irreversible dilatation of the bronchi and is characterised by chronic infection and associated inflammation. The prevalence of bronchiectasi...

    Authors: Ravishankar Chandrasekaran, Micheál Mac Aogáin, James D. Chalmers, Stuart J. Elborn and Sanjay H. Chotirmall

    Citation: BMC Pulmonary Medicine 2018 18:83

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  9. Content type: Research article

    Non-tuberculous mycobacteria (NTM) infection is an increasing problem worldwide. The epidemiology of NTM in most Asian countries is unknown. This study investigated the epidemiology, and clinical profile of in...

    Authors: Albert Y. H. Lim, Sanjay H. Chotirmall, Eric T. K. Fok, Akash Verma, Partha P. De, Soon Keng Goh, Ser Hon Puah, Daryl E. L. Goh and John A. Abisheganaden

    Citation: BMC Pulmonary Medicine 2018 18:85

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  10. Content type: Research article

    Lung transplantation is a well-established treatment for end-stage non-cystic fibrosis bronchiectasis (BR), though information regarding outcomes of transplantation remains limited. Our results of lung transpl...

    Authors: Jodie Birch, Syba S. Sunny, Katy L. M. Hester, Gareth Parry, F. Kate Gould, John H. Dark, Stephen C. Clark, Gerard Meachery, James Lordan, Andrew J. Fisher, Paul A. Corris and Anthony De Soyza

    Citation: BMC Pulmonary Medicine 2018 18:82

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  11. Content type: Editorial

    Bronchiectasis has an increasing profile within respiratory medicine. This chronic and irreversible airways disease is common but suffers from a lack of evidenced based therapy for patients and, a lack of unde...

    Authors: Sanjay H. Chotirmall and James D. Chalmers

    Citation: BMC Pulmonary Medicine 2018 18:76

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  12. Content type: Research article

    In people with cystic fibrosis infection with NonTuberculous Mycobacteria is of increasing prevalence. Mycobacterium abscessus complex is of particular concern and has been associated with adverse clinical outcom...

    Authors: Adrien Tissot, Matthew F. Thomas, Paul A. Corris and Malcolm Brodlie

    Citation: BMC Pulmonary Medicine 2018 18:86

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  13. Content type: Case report

    Pleuroparenchymal fibroelastosis (PPFE) is a very rare interstitial lung disease (ILD) characterized by progressive fibrotic lesions of the visceral pleura and the sub-pleural parenchyma, affecting predominant...

    Authors: D. Hassoun, S. Dirou, P. P. Arrigoni, C. Durant, M. Hamidou, A. Néel and C. Agard

    Citation: BMC Pulmonary Medicine 2018 18:73

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  14. Content type: Research article

    The most common cause of death of patients with idiopathic pulmonary fibrosis (IPF) has been reported to be the lung disease itself and mortality from IPF appears to be increasing. However, the causes of death...

    Authors: Miia Kärkkäinen, Hanna Nurmi, Hannu-Pekka Kettunen, Tuomas Selander, Minna Purokivi and Riitta Kaarteenaho

    Citation: BMC Pulmonary Medicine 2018 18:69

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  15. Content type: Research article

    The inherent risk of developing tuberculosis (TB) in HIV- infected individuals is further enhanced by hypovitaminosis D. Interventions that offset HIV-associated immune deterioration potentially arrest disease...

    Authors: Cuthbert Musarurwa, Lynn Sodai Zijenah, Doreen Zvipo Mhandire, Tsitsi Bandason, Kudakwashe Mhandire, Maria Mary Chipiti, Marshall Wesley Munjoma and Witmore Bayayi Mujaji

    Citation: BMC Pulmonary Medicine 2018 18:67

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  16. Content type: Research article

    Pirfenidone, a pleiotropic anti-fibrotic treatment, has been shown to slow down disease progression of idiopathic pulmonary fibrosis (IPF), a fatal and devastating lung disease. Rapamycin, an inhibitor of fibr...

    Authors: M. Molina-Molina, C. Machahua-Huamani, V. Vicens-Zygmunt, R. Llatjós, I. Escobar, E. Sala-Llinas, P. Luburich-Hernaiz, J. Dorca and A. Montes-Worboys

    Citation: BMC Pulmonary Medicine 2018 18:63

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  17. Content type: Research article

    Aspergillus fumigatus is frequently encountered in sputum samples of patients with cystic fibrosis (CF), which traditionally has been interpreted as saprophytic airway colonization. However, this mere bystander r...

    Authors: Johannes Träger, Volker Otto Melichar, Renate Meyer, Manfred Rauh, Christian Bogdan and Jürgen Held

    Citation: BMC Pulmonary Medicine 2018 18:52

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  18. Content type: Research article

    Interstitial lung disease (ILD) is a prognostic indicator of poor outcome in myositis. Although the pathogenesis of myositis-associated ILD is not well understood, neutrophils are thought to play a pivotal rol...

    Authors: Noriho Sakamoto, Hiroshi Ishimoto, Tomoyuki Kakugawa, Minoru Satoh, Tomoko Hasegawa, Shin Tanaka, Atsuko Hara, Shota Nakashima, Hirokazu Yura, Takuto Miyamura, Hanako Koyama, Towako Morita, Seiko Nakamichi, Yasushi Obase, Yuji Ishimatsu and Hiroshi Mukae

    Citation: BMC Pulmonary Medicine 2018 18:44

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  19. Content type: Research article

    Previous studies have suggested that antibodies against human leukocyte antigen (HLA) are associated with worse outcomes in lung transplantation. However, little is known about the factors associated with outc...

    Authors: Ji Eun Park, Chi Young Kim, Moo Suk Park, Joo Han Song, Young Sam Kim, Jin Gu Lee, Hyo Chae Paik and Song Yee Kim

    Citation: BMC Pulmonary Medicine 2018 18:45

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