Respiratory critical care

Section edited by Raffaele Scala

This section concerns all aspects dealing with pulmonary critically ill patients: models of acute setting ; epidemiology, monitoring and treatment of acute respiratory failure; patho-physiology and clinical applications of invasive e non-invasive mechanical ventilation; weaning strategies; morbidity and mortality; ethical problems; imaging and interventional procedures; nurse and physiotherapist's issues.

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  1. Research article

    Intravenous superoxide dismutase as a protective agent to prevent impairment of lung function induced by high tidal volume ventilation

    Positive-pressure mechanical ventilation is essential in assisting patients with respiratory failure in the intensive care unit and facilitating oxygenation in the operating room. However, it was also recogniz...

    Nan-Chun Wu, Fan-Ting Liao, Hao-min Cheng, Shih-Hsien Sung, Yu-Chun Yang and Jiun-Jr Wang

    BMC Pulmonary Medicine 2017 17:105

    Published on: 26 July 2017

  2. Case report

    Successful rescue combination of extracorporeal membrane oxygenation, high-frequency oscillatory ventilation and prone positioning for the management of severe methicillin-resistant Staphylococcus aureus pneumonia complicated by pneumothorax: a case report and literature review

    To describe the experience of combination therapy with extracorporeal membrane oxygenation(ECMO), high-frequency oscillatory ventilation(HFOV) and prone positioning in treating severe respiratory failure cause...

    Hangyong He, Hao Wang, Xuyan Li, Xiao Tang, Rui Wang, Bing Sun and Zhaohui Tong

    BMC Pulmonary Medicine 2017 17:103

    Published on: 20 July 2017

  3. Case report

    Monitoring the electric activity of the diaphragm during noninvasive positive pressure ventilation: a case report

    In patients with post-extubation respiratory distress, delayed reintubation may worsen clinical outcomes. Objective measures of extubation failure at the bedside are lacking, therefore clinical parameters are ...

    Fabia Diniz-Silva, Anna Miethke-Morais, Adriano M. Alencar, Henrique T. Moriya, Pedro Caruso, Eduardo L. V. Costa and Juliana C. Ferreira

    BMC Pulmonary Medicine 2017 17:91

    Published on: 17 June 2017

  4. Research article

    Single use and conventional bronchoscopes for Broncho alveolar lavage (BAL) in research: a comparative study (NCT 02515591)

    Broncho alveolar lavage (BAL) is widely used for investigative research to study innate, cellular and humoral immune responses, and in early phase drug trials. Conventional (multiple use) flexible bronchoscope...

    Seher Raza Zaidi, Andrea M. Collins, Elena Mitsi, Jesús Reiné, Kayleigh Davies, Angela D Wright, Jessica Owugha, Richard Fitzgerald, Amitava Ganguli, Stephen B Gordon, Daniela Mulari Ferreira and Jamie Rylance

    BMC Pulmonary Medicine 2017 17:83

    Published on: 5 May 2017

  5. Research article

    A new clinical algorithm scoring for management of suspected foreign body aspiration in children

    Foreign Body Aspiration (FBA) is a serious problem in children and delays in diagnosis and management can be devastating. The history is often vague, with subtle physical and chest radiograph abnormalities. Th...

    Ibrahim A. Janahi, Shabina Khan, Prem Chandra, Noora Al-Marri, Ammar Saadoon, Lolwa Al-Naimi, Maryam Al-Thani and William Greer

    BMC Pulmonary Medicine 2017 17:61

    Published on: 13 April 2017

  6. Case report

    Extracorporeal membrane oxygenation for avian influenza A (H7N9) patient with acute respiratory distress syndrome: a case report and short literature review

    Extracorporeal membrane oxygenation (ECMO) is performed as an acceptable life-saving bridging procedure in patients with severe acute respiratory distress syndrome (ARDS).To patients with avian influenza A (H7...

    Qi Nie, Ding-yu Zhang, Wen-juan Wu, Chao-lin Huang and Zheng-yi Ni

    BMC Pulmonary Medicine 2017 17:38

    Published on: 14 February 2017

  7. Research article

    IL-8 predicts early mortality in patients with acute hypercapnic respiratory failure treated with noninvasive positive pressure ventilation

    Patients with Acute Hypercapnic Respiratory Failure (AHRF) who are unresponsive to appropriate medical treatment, are often treated with Noninvasive Positive Pressure Ventilation (NPPV). Clinical predictors of...

    Brynja Jónsdóttir, Åsa Jaworowski, Carmen San Miguel and Olle Melander

    BMC Pulmonary Medicine 2017 17:35

    Published on: 8 February 2017

  8. Research article

    Hemodynamic effects of lung recruitment maneuvers in acute respiratory distress syndrome

    Clinical trials have, so far, failed to establish clear beneficial outcomes of recruitment maneuvers (RMs) on patient mortality in acute respiratory distress syndrome (ARDS), and the effects of RMs on the card...

    Anup Das, Mainul Haque, Marc Chikhani, Oana Cole, Wenfei Wang, Jonathan G. Hardman and Declan G. Bates

    BMC Pulmonary Medicine 2017 17:34

    Published on: 8 February 2017

  9. Research article

    Early exposure to hyperoxia and mortality in critically ill patients with severe traumatic injuries

    Hyperoxia is common early in the course of resuscitation of critically ill patients. It has been associated with mortality in some, but not all, studies of cardiac arrest patients and other critically ill coho...

    Derek W. Russell, David R. Janz, William L. Emerson, Addison K. May, Gordon R. Bernard, Zhiguo Zhao, Tatsuki Koyama and Lorraine B. Ware

    BMC Pulmonary Medicine 2017 17:29

    Published on: 3 February 2017

  10. Research article

    Effects of ventilator settings, nebulizer and exhalation port position on albuterol delivery during non-invasive ventilation: an in-vitro study

    Few studies have investigated the factors affecting aerosol delivery during non-invasive ventilation (NIV). Our aim was to investigate, using a bench-top model, the effect of different ventilator settings and ...

    Yuda Sutherasan, Lorenzo Ball, Pasquale Raimondo, Valentina Caratto, Elisa Sanguineti, Federico Costantino, Maurizio Ferretti, Robert M. Kacmarek and Paolo Pelosi

    BMC Pulmonary Medicine 2017 17:9

    Published on: 10 January 2017

  11. Research article

    End-tidal capnographic monitoring to detect apnea episodes during flexible bronchoscopy under sedation

    Apnea developing as a result of oversedation is a potential clinical problem in patients undergoing flexible bronchoscopy (FB) under sedation. However, there are no reports of evaluation using a standardized m...

    Tsukasa Ishiwata, Kenji Tsushima, Mai Fujie, Kenichi Suzuki, Kosuke Hirota, Mitsuhiro Abe, Naoko Kawata, Jiro Terada and Koichiro Tatsumi

    BMC Pulmonary Medicine 2017 17:7

    Published on: 7 January 2017

  12. Study protocol

    BreathDx – molecular analysis of exhaled breath as a diagnostic test for ventilator–associated pneumonia: protocol for a European multicentre observational study

    The diagnosis of ventilator-associated pneumonia (VAP) remains time-consuming and costly, the clinical tools lack specificity and a bedside test to exclude infection in suspected patients is unavailable. Breat...

    Pouline M. P. van Oort, Tamara Nijsen, Hans Weda, Hugo Knobel, Paul Dark, Timothy Felton, Nicholas J. W. Rattray, Oluwasola Lawal, Waqar Ahmed, Craig Portsmouth, Peter J. Sterk, Marcus J. Schultz, Tetyana Zakharkina, Antonio Artigas, Pedro Povoa, Ignacio Martin-Loeches…

    BMC Pulmonary Medicine 2017 17:1

    Published on: 3 January 2017

  13. Research article

    Non-invasive mechanical ventilation after heart surgery in children

    The purpose of the study was to analyze the characteristics and evolution of non-invasive mechanical ventilation (NIV) in the postoperative period of heart surgery in children.

    Sarah Fernández Lafever, Blanca Toledo, Miguel Leiva, Maite Padrón, Marina Balseiro, Angel Carrillo and Jesús López-Herce

    BMC Pulmonary Medicine 2016 16:167

    Published on: 29 November 2016

  14. Case report

    Diffuse persistent pulmonary interstitial emphysema secondary to mechanical ventilation in bronchiolitis

    Persistent interstitial pulmonary emphysema (PIE) is a rare disease and it is even more uncommon in full-term infants, like our patient. When conservative management is not successful, surgical treatment shoul...

    Blanca Toledo del Castillo, Isabel Gordillo, Elena Rubio García, Sarah Nicole Fernández Lafever, Rafael Gonzalez Cortés, Javier Urbano Villaescusa, Jorge López González, María José Solana García and Jesús López-Herce Cid

    BMC Pulmonary Medicine 2016 16:139

    Published on: 3 November 2016

  15. Research article

    Long-term outcome and health-related quality of life in difficult-to-wean patients with and without ventilator dependency at ICU discharge: a retrospective cohort study

    Long-term outcome and quality of life (QOL) in patients requiring prolonged mechanical ventilation after failure to wean in the ICU is scarcely documented. We aimed to evaluate long-term survival and QOL in pa...

    P. Depuydt, S. Oeyen, S. De Smet, S. De Raedt, D. Benoit, J. Decruyenaere and E. Derom

    BMC Pulmonary Medicine 2016 16:133

    Published on: 27 September 2016

  16. Research article

    Noninvasive versus invasive mechanical ventilation for immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis

    To determine the effects of noninvasive mechanical ventilation (NIV) compared with invasive mechanical ventilation (IMV) as the initial mechanical ventilation on clinical outcomes when used for treatment of ac...

    Tao Wang, Lixi Zhang, Kai Luo, Jianqiang He, Yong Ma, Zongru Li, Na Zhao, Qun Xu, Yi Li and Xuezhong Yu

    BMC Pulmonary Medicine 2016 16:129

    Published on: 27 August 2016

  17. Research article

    Influence of weaning methods on the diaphragm after mechanical ventilation in a rat model

    Mechanical ventilation (MV) is associated with diaphragm weakness, a phenomenon termed ventilator-induced diaphragmatic dysfunction. Weaning should balance diaphragmatic loading as well as prevention of overlo...

    Christian S. Bruells, Thomas Breuer, Karen Maes, Ingmar Bergs, Christian Bleilevens, Gernot Marx, Joachim Weis, Ghislaine Gayan-Ramirez and Rolf Rossaint

    BMC Pulmonary Medicine 2016 16:127

    Published on: 24 August 2016

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