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  1. Systemic sclerosis (SSc) is a severe rheumatic disease of the interstitial tissue, in which heart and lung involvement can lead to disease-specific mortality. Our study tests the hypothesis that in addition to...

    Authors: Ralf Ewert, Till Ittermann, Dirk Habedank, Matthias Held, Tobias J. Lange, Michael Halank, Jörg Winkler, Sven Gläser, Horst Olschewski and Gabor Kovacs
    Citation: BMC Pulmonary Medicine 2019 19:230
  2. Globally, tuberculosis (TB) lasts a major public health concern. Using feasible strategies to estimate TB infectious periods is crucial. The aim of this study was to determine the magnitude of TB infectious pe...

    Authors: Mulusew Andualem Asemahagn, Getu Degu Alene and Solomon Abebe Yimer
    Citation: BMC Pulmonary Medicine 2019 19:229
  3. Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial pneumonia with an unpredictable course. The aims of this study were to retrospectively re-evaluate a cohort of patients with IPF according to t...

    Authors: Miia Kärkkäinen, Hannu-Pekka Kettunen, Hanna Nurmi, Tuomas Selander, Minna Purokivi and Riitta Kaarteenaho
    Citation: BMC Pulmonary Medicine 2019 19:228
  4. Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities. The main causes of COPD are Gene-env...

    Authors: Yadira Velasco-Torres, Victor Ruiz-López, Oliver Pérez-Bautista, Ivette Buendía-Roldan, Alejandra Ramírez-Venegas, Julia Pérez-Ramos, Ramcés Falfán-Valencia, Carlos Ramos and Martha Montaño
    Citation: BMC Pulmonary Medicine 2019 19:227
  5. To quantify the financial cost of pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc).

    Authors: Kathleen Morrisroe, Wendy Stevens, Joanne Sahhar, Gene-Siew Ngian, Nava Ferdowsi, Dylan Hansen, Shreeya Patel, Catherine L. Hill, Janet Roddy, Jennifer Walker, Susanna Proudman and Mandana Nikpour
    Citation: BMC Pulmonary Medicine 2019 19:226
  6. To study the effects of different positive end expiratory pressure (PEEP) on blood pressure and heart function in elderly patients with hypertension.

    Authors: Lili Zhou, Guoen Cai, Zhihui Xu, Qinyong Weng, Qinyong Ye and Cunrong Chen
    Citation: BMC Pulmonary Medicine 2019 19:224
  7. The CAnadian REgistry for Pulmonary Fibrosis (CARE-PF) is a multi-center, prospective registry designed to study the natural history of fibrotic interstitial lung disease (ILD) in adults. The aim of this cross...

    Authors: J. H. Fisher, M. Kolb, M. Algamdi, J. Morisset, K. A. Johannson, S. Shapera, P. Wilcox, T. To, M. Sadatsafavi, H. Manganas, N. Khalil, N. Hambly, A. J. Halayko, A. S. Gershon, C. D. Fell, G. Cox…
    Citation: BMC Pulmonary Medicine 2019 19:223
  8. Idiopathic pulmonary fibrosis (IPF) is a disease with poor prognosis mainly affecting males. Differences in clinical presentation between genders may be important both for the diagnostic work-up and for follow...

    Authors: Dimitrios Kalafatis, Jing Gao, Ida Pesonen, Lisa Carlson, C. Magnus Sköld and Giovanni Ferrara
    Citation: BMC Pulmonary Medicine 2019 19:222
  9. Physical activity is recommended in the management of cystic fibrosis (CF). The aim of this study was to explore motives, barriers and enablers to physical activity among this population. Methods: Twelve parti...

    Authors: S. Denford, D. M. Hill, K. A. Mackintosh, M. A. McNarry, A. R. Barker and C. A. Williams
    Citation: BMC Pulmonary Medicine 2019 19:220
  10. Malignant central airway obstruction (CAO) occurs in approximately 20–30% of patients with lung cancer and is associated with debilitating symptoms and poor prognosis. Multimodality therapeutic bronchoscopy ca...

    Authors: Coral X. Giovacchini, Edward R. Kessler, Christopher M. Merrick, Junheng Gao, Xiaofei Wang, Momen M. Wahidi, Scott L. Shofer, George Z. Cheng and Kamran Mahmood
    Citation: BMC Pulmonary Medicine 2019 19:219
  11. The dysfunction of airway epithelial barrier is closely related to the pathogenesis of asthma. Secreted Hsp90α participates in inflammation and Hsp90 inhibitor protects endothelial dysfunction. In the current ...

    Authors: Cuiping Ye, Chaowen Huang, Mengchen Zou, Yahui Hu, Lishan Luo, Yilan Wei, Xuan Wan, Haijin Zhao, Wei Li, Shaoxi Cai and Hangming Dong
    Citation: BMC Pulmonary Medicine 2019 19:218
  12. Eosinophilic lung diseases represent a heterogeneous group of disorders with prominent infiltrate of eosinophils in lung interstitium and alveolar spaces. Peripheral blood eosinophilia is often present. Infect...

    Authors: Magda Zanelli, Maxwell Smith, Maurizio Zizzo, Angelo Carloni, Riccardo Valli, Loredana De Marco, Moira Foroni, Andrea Palicelli, Giovanni Martino and Stefano Ascani
    Citation: BMC Pulmonary Medicine 2019 19:216
  13. Acute exacerbation (AE) is the major cause of morbidity and mortality in patients with idiopathic pulmonary fibrosis (IPF). AEs also occur in other forms of fibrosing interstitial lung disease (fILD). The clin...

    Authors: Mengshu Cao, Jian Sheng, Xiaohua Qiu, Dandan Wang, Dongmei Wang, Yang Wang, Yonglong Xiao and Hourong Cai
    Citation: BMC Pulmonary Medicine 2019 19:215
  14. Flexible bronchoscopy enables visualization of the respiratory airway mucosa from the oropharynx to third generation branching of the tracheobronchial tree. Bronchoscopic diagnoses vary from one locality to th...

    Authors: Deus A. Ndilanha, Grace A. Shayo, Ramadhan Hassan, Moses Byomuganyizi and Leonard E. K. Lema
    Citation: BMC Pulmonary Medicine 2019 19:214
  15. Fibrosing, non-idiopathic pulmonary fibrosis (non-IPF) interstitial lung diseases (fILDs) are a heterogeneous group of diseases characterized by a different amount of inflammation and fibrosis. Therapy is curr...

    Authors: Sebastiano Emanuele Torrisi, Nicolas Kahn, Julia Wälscher, Nilab Sarmand, Markus Polke, Kehler Lars, Monika Eichinger, Claus Peter Heussel, Stefano Palmucci, Francesca Maria Sambataro, Gianluca Sambataro, Domenico Sambataro, Carlo Vancheri and Michael Kreuter
    Citation: BMC Pulmonary Medicine 2019 19:213
  16. A three-drug regimen (macrolide, ethambutol, and rifampicin) is recommended for the treatment of Mycobacterium avium complex pulmonary disease (MAC-PD). Although macrolide has proven efficacy, the role of ethambu...

    Authors: Hyung-Jun Kim, Jong Sik Lee, Nakwon Kwak, Jaeyoung Cho, Chang-Hoon Lee, Sung Koo Han and Jae-Joon Yim
    Citation: BMC Pulmonary Medicine 2019 19:212
  17. Anti-tuberculosis therapy requires at least six-month treatment with continuous administration of combined antibiotics, including isoniazid, rifampicin, pyrazinamide, and ethambutol. The long-term exposure to ...

    Authors: Wenpei Shi, Yi Hu, Xubin Zheng, Zhu Ning, Meiying Wu, Fan Xia, Stefanie Prast-Nielsen, Yue O. O. Hu and Biao Xu
    Citation: BMC Pulmonary Medicine 2019 19:211
  18. Spontaneous remission (SR) of cancer is a very rare phenomenon of unknown mechanism. In particular, SR of non-small cell lung cancer (NSCLC) has been scarcely reported. We present the case of a 74-year-old wom...

    Authors: Hee-Young Yoon, Heae Surng Park, Min Sun Cho, Sung Shin Shim, Yookyung Kim and Jin Hwa Lee
    Citation: BMC Pulmonary Medicine 2019 19:210
  19. Lung cancer is one of the most incident neoplastic diseases, and a leading cause of death for cancer worldwide. Knowledge of the incidence of druggable genetic alterations, their correlation with clinical and ...

    Authors: Maria Colombino, Panagiotis Paliogiannis, Antonio Cossu, Davide Adriano Santeufemia, Maria Cristina Sini, Milena Casula, Grazia Palomba, Antonella Manca, Marina Pisano, Valentina Doneddu and Giuseppe Palmieri
    Citation: BMC Pulmonary Medicine 2019 19:209
  20. The expiratory time constant (RCEXP), which is defined as the product of airway resistance and lung compliance, enable us to assess the mechanical properties of the respiratory system in mechanically ventilated p...

    Authors: Takamitsu Ikeda, Yasuhiro Yamauchi, Kanji Uchida, Koji Oba, Takahide Nagase and Yoshitsugu Yamada
    Citation: BMC Pulmonary Medicine 2019 19:208
  21. To compare the therapeutic value of a bronchial blocker (BB) with a double-lumen tube (DLT) in minimally invasive cardiac surgery (MICS).

    Authors: Chuncheng Zhang, Jing Yue, Mingyue Li, Wei Jiang, Yu Pan, Zhimin Song, Cailian Shi, Weixuan Fan and Zhenxiang Pan
    Citation: BMC Pulmonary Medicine 2019 19:207

    The Retraction Note to this article has been published in BMC Pulmonary Medicine 2020 20:322

  22. Quantifying morphologic changes is critical to our understanding of the pathophysiology of the lung. Mean linear intercept (MLI) measures are important in the assessment of clinically relevant pathology, such ...

    Authors: George Crowley, Sophia Kwon, Erin J. Caraher, Syed Hissam Haider, Rachel Lam, Prag Batra, Daniel Melles, Mengling Liu and Anna Nolan
    Citation: BMC Pulmonary Medicine 2019 19:206
  23. The critical management of advanced non-small-cell lung carcinoma (NSCLC), especially when complicated by severe airway stenosis, is difficult and often leads to high clinical risks and medical costs.

    Authors: Ai-Gui Jiang, Hui-Yu Lu and Zhong-Qi Ding
    Citation: BMC Pulmonary Medicine 2019 19:205
  24. To explore patterns of brain structural alteration in chronic obstructive pulmonary disease (COPD) patients with different levels of lung function impairment and the associations of those patterns with cogniti...

    Authors: Minmin Yin, Haibao Wang, Xianwei Hu, Xiaoshu Li, Guanghe Fei and Yongqiang Yu
    Citation: BMC Pulmonary Medicine 2019 19:203
  25. The published data on the association between β2-adrenergic receptor gene polymorphisms and asthma susceptibility are inconclusive. To derive a more precise estimation of this association, a meta-analysis was ...

    Authors: Songlin Zhao, Wei Zhang and Xiuhong Nie
    Citation: BMC Pulmonary Medicine 2019 19:202
  26. Delay in diagnosis and treatment of pulmonary tuberculosis (PTB) leads to severe disease, adverse outcomes and increased transmission. Assessing the extent of delay and its effect on disease progression in TB ...

    Authors: Fentabil Getnet, Meaza Demissie, Alemayehu Worku, Tesfaye Gobena, Rea Tschopp, Michael Girmachew, Gebeyehu Assefa and Berhanu Seyoum
    Citation: BMC Pulmonary Medicine 2019 19:201
  27. Lung injury is common in post-cardiac arrest syndrome, and is associated with increased morbidity and mortality. The aim of this study was to evaluate the effect of mild hypothermia on lung injury after cardia...

    Authors: Chunshuang Wu, Jiefeng Xu, Xiaohong Jin, Qijiang Chen, Zilong Li and Mao Zhang
    Citation: BMC Pulmonary Medicine 2019 19:198
  28. Following publication of the original article [1], the authors flagged that name of the author ‘Batoul Khoundabi’ had been provided with an incorrect spelling: ‘Batoutl’ was given in place of ‘Batoul’.

    Authors: Majid Malekmohammad, Gert Folkerts, Babak Sharif Kashani, Parisa Adimi Naghan, Zahra Habibi Dastenae, Batoul Khoundabi, Johan Garssen, Esmaeil Mortaz and Ian M. Adcock
    Citation: BMC Pulmonary Medicine 2019 19:197

    The original article was published in BMC Pulmonary Medicine 2019 19:188

  29. Epidemiologic studies have shown inconsistent conclusions about the effect of ulinastain treatment for acute respiratory distress syndrome (ARDS). It is necessary to perform a meta-analysis of ulinastatin’s ra...

    Authors: Xiangyun Zhang, Zhaozhong Zhu, Weijie Jiao, Wei Liu, Fang Liu and Xi Zhu
    Citation: BMC Pulmonary Medicine 2019 19:196
  30. Dose intensity and dose density of first line Platinum and Etoposide (PE) do not influence Overall Survival (OS) of Small Cell Lung Cancer (SCLC) patients. The effect of treatment length, however, remains uncl...

    Authors: Mostafa Sallam, Helen Wong and Carles Escriu
    Citation: BMC Pulmonary Medicine 2019 19:195
  31. Myeloperoxidase anti-neutrophil cytoplasmic antibody-related nephritis (MPO-ANCA nephritis) is occasionally accompanied by lung abnormalities such as pulmonary fibrosis. However, the clinical features of pulmo...

    Authors: Toshikazu Watanabe, Tomoyuki Minezawa, Midori Hasegawa, Yasuhiro Goto, Takuya Okamura, Yosuke Sakakibara, Yoshikazu Niwa, Atsushi Kato, Masamichi Hayashi, Sumito Isogai, Masashi Kondo, Naoki Yamamoto, Naozumi Hashimoto and Kazuyoshi Imaizumi
    Citation: BMC Pulmonary Medicine 2019 19:194
  32. Radial endobronchial ultrasound (R-EBUS)-guided transbronchial biopsy (TBB) is a common diagnostic modality for peripheral pulmonary lesions; however, there is uncertainty about the optimal sequence of TBB and...

    Authors: Chun-Ta Huang, Yi-Ju Tsai, Chao-Chi Ho and Chong-Jen Yu
    Citation: BMC Pulmonary Medicine 2019 19:193
  33. Connective tissue disease-associated interstitial lung disease (CTD-ILD) is associated with reduced quality of life and poor prognosis. Prior studies have not identified a consistent combination of variables t...

    Authors: Chrystal Chan, Christopher J. Ryerson, James V. Dunne and Pearce G. Wilcox
    Citation: BMC Pulmonary Medicine 2019 19:192
  34. IgG4-related disease (IgG4-RD) is a systemic autoimmune disease that can affect multiple organs of the body. Pulmonary manifestations of IgG4-RD include pulmonary solid nodules, thickening of bronchovascular b...

    Authors: Xiuling Wang, Jun Wan, Ling Zhao, Jiping Da, Bin Cao and Zhenguo Zhai
    Citation: BMC Pulmonary Medicine 2019 19:191
  35. In 2015, South Korea experienced an outbreak of Middle East respiratory syndrome (MERS), and our hospital experienced a nosocomial MERS infection. We performed a comprehensive analysis to identify the MERS tra...

    Authors: Hyun Kyun Ki, Sang Kuk Han, Jun Seong Son and Sang O Park
    Citation: BMC Pulmonary Medicine 2019 19:190
  36. Limited data exists regarding healthcare utilization, medical expenses, and prognosis of pulmonary hypertension (PH) according to the World Health Organization (WHO) classification. We aimed to investigate mor...

    Authors: In-Chang Hwang, Goo-Yeong Cho, Hong-Mi Choi, Yeonyee E. Yoon, Jin Joo Park, Jun-Bean Park, Seung-Pyo Lee, Hyung-Kwan Kim, Yong-Jin Kim and Dae-Won Sohn
    Citation: BMC Pulmonary Medicine 2019 19:189
  37. Idiopathic pulmonary arterial hypertension (IPAH) is a fatal illness. Despite many improvements in the treatment of these patients, there is no unique prognostic variable available to track these patients. The...

    Authors: Majid Malekmohammad, Gert Folkerts, Babak Sharif Kashani, Parisa Adimi Naghan, Zahra Habibi Dastenae, Batoul Khoundabi, Johan Garssen, Esmaeil Mortaz and Ian M. Adcock
    Citation: BMC Pulmonary Medicine 2019 19:188

    The Correction to this article has been published in BMC Pulmonary Medicine 2019 19:197

  38. Patient awareness of asthma severity is important for optimal asthma management. However, there is often a discrepancy between physician assessment of asthma control based on guidelines and patient discernment...

    Authors: Tewodros H. Gebremariam, Charles B. Sherman and Neil W. Schluger
    Citation: BMC Pulmonary Medicine 2019 19:187
  39. There is evidence of an association between inflammatory bowel disease (IBD) and lung conditions such as chronic obstructive pulmonary disease (COPD). This systematic review and meta-analysis explored the risk...

    Authors: Gonzalo Labarca, Lauren Drake, Gloria Horta, Michael A. Jantz, Hiren J. Mehta, Sebastian Fernandez-Bussy, Erik Folch, Adnan Majid and Michael Picco
    Citation: BMC Pulmonary Medicine 2019 19:186
  40. Diffuse alveolar haemorrhage (DAH) is characterized by the diffuse accumulation of red blood cells within the alveoli, presence of ground glass opacities and/or consolidation on computed tomography (CT). Aside...

    Authors: Anna Stainer, Alex Rice, Anand Devaraj, Joseph Luke Barnett, Jacqueline Donovan, Maria Kokosi, Andrew Gordon Nicholson, Tom Cairns, Athol Umfrey Wells and Elisabetta Augusta Renzoni
    Citation: BMC Pulmonary Medicine 2019 19:185
  41. Chronic obstructive pulmonary disease (COPD) and pulmonary tuberculosis (PTB) share a number of common risk factors, including innate immunity-related genetic factors. In the present study, we compared the rol...

    Authors: Zhongqi Li, Xuhua Mao, Qiao Liu, Huan Song, Biyu He, Peiyi Shi, Qun Zhang, Xiaona Li and Jianming Wang
    Citation: BMC Pulmonary Medicine 2019 19:184
  42. Fibrotic interstitial lung disease (FILD) patients are typically dyspneic and exercise-intolerant with consequent impairment of health-related quality of life (HRQoL). Respiratory muscle dysfunction is among t...

    Authors: Pauliane Vieira Santana, Leticia Zumpano Cardenas, André Luis Pereira de Albuquerque, Carlos Roberto Ribeiro de Carvalho and Pedro Caruso
    Citation: BMC Pulmonary Medicine 2019 19:183
  43. Chronic obstructive pulmonary disease (COPD) is one of the major public health problems worldwide. Despite an increasing burden of COPD in the world, it is often a neglected disease in low income countries and...

    Authors: Gashaw Garedew Woldeamanuel, Alemu Basazin Mingude and Teshome Gensa Geta
    Citation: BMC Pulmonary Medicine 2019 19:181

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