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  1. Since the first outbreak of a respiratory illness caused by H1N1 virus in Mexico, several reports have described the need of intensive care or extracorporeal membrane oxygenation (ECMO) assistance in young and...

    Authors: Giovanni Cianchi, Manuela Bonizzoli, Andrea Pasquini, Massimo Bonacchi, Giovanni Zagli, Marco Ciapetti, Guido Sani, Stefano Batacchi, Simona Biondi, Pasquale Bernardo, Chiara Lazzeri, Valtere Giovannini, Alberta Azzi, Rosanna Abbate, Gianfranco Gensini and Adriano Peris

    Citation: BMC Pulmonary Medicine 2011 11:2

    Content type: Research article

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  2. Airway Bypass is a catheter-based, bronchoscopic procedure in which new passageways are created that bypass the collapsed airways, enabling trapped air to exit the lungs. The Exhale Airway Stents for Emphysema...

    Authors: Pallav L Shah, Dirk-Jan Slebos, Paulo FG Cardoso, Edward J Cetti, Gerhard W Sybrecht and Joel D Cooper

    Citation: BMC Pulmonary Medicine 2011 11:1

    Content type: Study protocol

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  3. Smoking is the major etiologic factor in COPD, yet the exact underlying pathogenetic mechanisms have not been elucidated. Since a few years, there is mounting evidence that a specific immune response, partly p...

    Authors: Corry-Anke Brandsma, Wim Timens, Marie Geerlings, Henrike Jekel, Dirkje S Postma, Machteld N Hylkema and Huib AM Kerstjens

    Citation: BMC Pulmonary Medicine 2010 10:64

    Content type: Research article

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  4. Breathlessness is a debilitating and distressing symptom in a wide variety of diseases and still a difficult symptom to manage. An integrative review of systematic reviews of non-pharmacological and pharmacolo...

    Authors: Chris D Bailey, Richard Wagland, Rasha Dabbour, Ann Caress, Jaclyn Smith and Alex Molassiotis

    Citation: BMC Pulmonary Medicine 2010 10:63

    Content type: Research article

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  5. Salamanca, Mexico occupied fourth place nationally in contaminating emissions. The aim of the study was to determine the impact of air pollution on the frequency of pulmonary function alterations and respirato...

    Authors: Benigno Linares, Juan M Guizar, Norma Amador, Alfonso Garcia, Victor Miranda, Jose R Perez and Rocío Chapela

    Citation: BMC Pulmonary Medicine 2010 10:62

    Content type: Research article

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  6. Smokers usually have a lower Body Mass Index (BMI) when compared to non-smokers. Such a relationship, however, has not been fully studied in obese and morbidly obese patients. The objective of this study was t...

    Authors: Raquel Chatkin, Claudio C Mottin and José M Chatkin

    Citation: BMC Pulmonary Medicine 2010 10:61

    Content type: Research article

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  7. Pulmonary function testing is a key procedure in the work-up of patients who are suspected of having asthma and chronic obstructive lung disease (COPD). Therein, clinical visits and pulmonary function tests (P...

    Authors: Frank J Visser, Milena JMM van der Vegt, Gert Jan van der Wilt and Julius P Janssen

    Citation: BMC Pulmonary Medicine 2010 10:60

    Content type: Research article

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  8. Monomers of the collectin surfactant associated protein-A (SP-A) are arranged in trimers and higher oligomers. The state of oligomerization differs between individuals and likely affects SP-A's functional prop...

    Authors: Stefanie M Heinrich and Matthias Griese

    Citation: BMC Pulmonary Medicine 2010 10:59

    Content type: Research article

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  9. Several studies have been published in the literature on the diagnostic accuracy of NT-pro-BNP for pleural effusions from heart failure in the last decade. The purpose of our study was to perform a systematic ...

    Authors: Surinder Janda and John Swiston

    Citation: BMC Pulmonary Medicine 2010 10:58

    Content type: Research article

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  10. Mechanical ventilation augments lung inflammation resulting from exposure to microbial products. The objective of this study was to test the hypothesis that ventilator-associated immune modulation requires MyD...

    Authors: Carrie D Chun, W Conrad Liles, Charles W Frevert, Robb W Glenny and William A Altemeier

    Citation: BMC Pulmonary Medicine 2010 10:57

    Content type: Research article

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  11. Pseudomonas aeruginosa infections are associated with progressive life threatening decline of lung function in cystic fibrosis sufferers. Growth of Ps. aeruginosa releases a "grape-like" odour that has been iden...

    Authors: Amy J Scott-Thomas, Mona Syhre, Philip K Pattemore, Michael Epton, Richard Laing, John Pearson and Stephen T Chambers

    Citation: BMC Pulmonary Medicine 2010 10:56

    Content type: Research article

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  12. We examined the influence of overweight and obesity on pulmonary function, exercise tolerance, quality of life and response to pulmonary rehabilitation in COPD.

    Authors: Francesco Sava, Louis Laviolette, Sarah Bernard, Marie-Josée Breton, Jean Bourbeau and François Maltais

    Citation: BMC Pulmonary Medicine 2010 10:55

    Content type: Research article

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  13. Kikuchi-Fujimoto's disease (KFD), also called histiocytic necrotizing lymphadenitis, is a rare, idiopathic and self-limited condition usually characterized by cervical lymphadenopathy and fever, most often aff...

    Authors: Alberto Garcia-Zamalloa, Jorge Taboada-Gomez, Pilar Bernardo-Galán, Fernandez-Martinez Magdalena, Laura Zaldumbide-Dueñas and Mario Ugarte-Maiztegui

    Citation: BMC Pulmonary Medicine 2010 10:54

    Content type: Case report

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  14. Pulmonary surfactant D (SP-D) has important regulatory functions for innate immunity and has been implicated as a biomarker for chronic obstructive pulmonary disease (COPD). We hypothesized that COPD patients ...

    Authors: Jayaji M Moré, Dennis R Voelker, Lori J Silveira, Michael G Edwards, Edward D Chan and Russell P Bowler

    Citation: BMC Pulmonary Medicine 2010 10:53

    Content type: Research article

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  15. The ability to objectively differentiate exacerbations of chronic obstructive pulmonary disease (COPD) from day-to-day symptom variations would be an important development in clinical practice and research. We...

    Authors: John R Hurst, Gavin C Donaldson, Jennifer K Quint, James JP Goldring, Anant RC Patel and Jadwiga A Wedzicha

    Citation: BMC Pulmonary Medicine 2010 10:52

    Content type: Research article

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  16. A significant genetic component has been described for idiopathic pulmonary fibrosis (IPF). The R131H (rs1801274) polymorphism of the IgG receptor FcγRIIa determines receptor affinity for IgG subclasses and is...

    Authors: Stylianos Bournazos, Jacob Grinfeld, Karen M Alexander, John T Murchison, William A Wallace, Pauline McFarlane, Nikhil Hirani, A John Simpson, Ian Dransfield and Simon P Hart

    Citation: BMC Pulmonary Medicine 2010 10:51

    Content type: Research article

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  17. International guidelines recommend long-acting bronchodilators in patients who remain symptomatic despite adequate treatment with short-acting bronchodilators. The purpose of this study is to estimate the effe...

    Authors: Ann Van den Bruel, Jeannine Gailly and Mattias Neyt

    Citation: BMC Pulmonary Medicine 2010 10:50

    Content type: Research article

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  18. Gastro-oesophageal reflux disease (GORD) symptoms are common in asthma and have been extensively studied, but less so in the Asian continent. Reflux-associated respiratory symptoms (RARS) have, in contrast, be...

    Authors: Lakmali D Amarasiri, Arunasalam Pathmeswaran, H Janaka de Silva and Channa D Ranasinha

    Citation: BMC Pulmonary Medicine 2010 10:49

    Content type: Research article

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  19. Tiotropium is reimbursed since March 2004 in Belgium for the treatment of Chronic Obstructive Pulmonary Disease (COPD). Questions however remain on this product's value for money. The purpose of this study is ...

    Authors: Mattias Neyt, Stephan Devriese, Nancy Thiry and Ann Van den Bruel

    Citation: BMC Pulmonary Medicine 2010 10:47

    Content type: Research article

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  20. As more patients with cystic fibrosis (CF) reach adulthood and participate in age-appropriate activities (e.g. employment, dating), disclosure of medical status becomes more important. This study assessed rate...

    Authors: Avani C Modi, Alexandra L Quittner and Michael P Boyle

    Citation: BMC Pulmonary Medicine 2010 10:46

    Content type: Research article

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  21. Pneumonia, and particularly nosocomial (NP) and ventilator-associated pneumonias (VAP), results in high morbidity and costs. NPs in particular are likely to be caused by Pseudomonas aeruginosa (PA), ~20% of which...

    Authors: Marya D Zilberberg, Joyce Chen, Samir H Mody, Andrew M Ramsey and Andrew F Shorr

    Citation: BMC Pulmonary Medicine 2010 10:45

    Content type: Research article

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  22. Chlamydia pneumoniae (C pn) infection causes an acute inflammation in the respiratory system that may become persistent, but little is known about the long-term respiratory effects of C pn infections. Aim: To es...

    Authors: Thorarinn Gislason, Vilmundur Guðnason, Bryndis Benediktsdottir, Isleifur Olafsson, Thor Aspelund, Bjarni Thjodleifsson and Christer Janson

    Citation: BMC Pulmonary Medicine 2010 10:44

    Content type: Research article

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  23. Asthma in children is an emerging public health problem in South America. So far, research in this part of the world is limited. This paper presents the methodology and description of the data acquisition of a...

    Authors: Anja Boneberger, Katja Radon, Jennifer Baer, Leonie Kausel, Michael Kabesch, Daniel Haider, Rudolf Schierl, Rüdiger von Kries and Mario Calvo

    Citation: BMC Pulmonary Medicine 2010 10:43

    Content type: Study protocol

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  24. We assessed the relationship between physiologic parameters, computed tomography patterns, 6 minute walk distance (6MWD) and the distance-saturation product [DSP; defined as the product of the 6MWD and the low...

    Authors: Esam H Alhamad, Shaffi Ahmad Shaik, Majdy M Idrees, Mohammed O Alanezi and Arthur C Isnani

    Citation: BMC Pulmonary Medicine 2010 10:42

    Content type: Research article

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  25. Despite optimal pharmacological therapy and pulmonary rehabilitation, patients with COPD continue to be breathless. There is a need to develop additional strategies to alleviate symptoms. Learning to sing requ...

    Authors: Victoria M Lord, Phoene Cave, Victoria J Hume, Elizabeth J Flude, Amanda Evans, Julia L Kelly, Michael I Polkey and Nicholas S Hopkinson

    Citation: BMC Pulmonary Medicine 2010 10:41

    Content type: Research article

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  26. Proteolysis of matrix components, in particular elastin, is a major contributing factor to the development of lung diseases such as emphysema and chronic obstructive pulmonary disease (COPD). MMP-12 (macrophag...

    Authors: Peter LaPan, Jeff Brady, Christal Grierson, Margaret Fleming, Doug Miller, Joe Sypek and Bin Fu

    Citation: BMC Pulmonary Medicine 2010 10:40

    Content type: Technical advance

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  27. Clinical and experimental data suggest that the inflammatory response is impaired in diabetics and can be modulated by insulin. The present study was undertaken to investigate the role of insulin on the early ...

    Authors: Joilson O Martins, Carlos AL Campos, José WMC Cruz, Simone Manzolli, Venâncio AF Alves, Elcio O Vianna, Sonia Jancar and Paulina Sannomiya

    Citation: BMC Pulmonary Medicine 2010 10:39

    Content type: Research article

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  28. Inadequate glucose control may be simultaneously associated with inflammation and decreased lung function in type 2 diabetes. We evaluated if lung function is worse in patients with inadequate glucose control,...

    Authors: Rodolfo J Dennis, Dario Maldonado, Maria X Rojas, Pablo Aschner, Martin Rondón, Laura Charry and Alejandro Casas

    Citation: BMC Pulmonary Medicine 2010 10:38

    Content type: Research article

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  29. Bronchial Hyperresponsiveness (BHR) is considered a hallmark of asthma. Other methods are helpful in epidemiological respiratory health studies including Fractional Exhaled Nitric Oxide (FENO) and Eosinophils ...

    Authors: Valérie Demange, Pascal Wild, Denis Zmirou-Navier, Paul Tossa, Abraham Bohadana, Annick Barbaud and Christophe Paris

    Citation: BMC Pulmonary Medicine 2010 10:37

    Content type: Research article

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  30. The Eosinophil Cationic Protein (ECP) is a potent multifunctional protein. Three common polymorphisms are present in the ECP gene, which determine the function and production of the protein. The aim was to stu...

    Authors: Ulla-Britt Jönsson, Lena Douhan Håkansson, Rain Jõgi, Christer Janson and Per Venge

    Citation: BMC Pulmonary Medicine 2010 10:36

    Content type: Research article

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  31. Chronic obstructive pulmonary disease (COPD) affects independence and survival in the general population, but it is unknown to which extent this conclusion applies to elderly people with mild disease. The aim ...

    Authors: Claudio Pedone, Simone Scarlata, Claudio Sorino, Francesco Forastiere, Vincenzo Bellia and Raffaele Antonelli Incalzi

    Citation: BMC Pulmonary Medicine 2010 10:35

    Content type: Research article

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  32. Aspirin-intolerant asthma (AIA), which is caused by non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin, causes lung inflammation and reversal bronchi reduction, leading to difficulty in breathing. ...

    Authors: Jason Yongha Kim, Jeong Hyun Kim, Tae Joon Park, Joon Seol Bae, Jin Sol Lee, Charisse Flerida Pasaje, Byung Lae Park, Hyun Sub Cheong, Jong-Sook Park, Sung-Woo Park, Soo-Taek Uh, Mi-Kyeong Kim, Inseon S Choi, Sang Heon Cho, Byoung Whui Choi, Choon-Sik Park…

    Citation: BMC Pulmonary Medicine 2010 10:34

    Content type: Research article

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  33. Chronic obstructive pulmonary disease (COPD) and a high body mass index (BMI) can both affect pulmonary volumes as well as exercise tolerance, but their combined effect on these outcomes is not well known. The...

    Authors: Louis Laviolette, Francesco Sava, Denis E O'Donnell, Katherine A Webb, Alan L Hamilton, Steven Kesten and François Maltais

    Citation: BMC Pulmonary Medicine 2010 10:33

    Content type: Research article

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  34. Exertional dyspnea is the most prominent and disabling feature in idiopathic pulmonary fibrosis (IPF). The Medical Research Chronic (MRC) chronic dyspnea score as well as physiological measurements obtained du...

    Authors: Effrosyni D Manali, Panagiotis Lyberopoulos, Christina Triantafillidou, Likourgos F Kolilekas, Christina Sotiropoulou, Joseph Milic-Emili, Charis Roussos and Spyros A Papiris

    Citation: BMC Pulmonary Medicine 2010 10:32

    Content type: Research article

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  35. Both Peak Oxygen Uptake (peak VO2), from cardiopulmonary exercise testing (CPET) and the distance walked during a Six-Minute Walk Test (6 MWD) are used for following the natural history of various diseases, ti...

    Authors: Robert M Ross, Jayasimha N Murthy, Istvan D Wollak and Andrew S Jackson

    Citation: BMC Pulmonary Medicine 2010 10:31

    Content type: Research article

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  36. Airway epithelial cells are critical in host defense against bacteria including Mycoplasma pneumoniae (Mp) in chronic obstructive pulmonary disease (COPD) and asthma. β2-agonists are mainstay of COPD and asthma t...

    Authors: Claire A Gross, Russell P Bowler, Rebecca M Green, Andrew R Weinberger, Christina Schnell and Hong Wei Chu

    Citation: BMC Pulmonary Medicine 2010 10:30

    Content type: Research article

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  37. Asthma management guidelines recommend a stepwise approach to instituting and adjusting anti-inflammatory controller therapy for children with asthma. The objective of this retrospective observational study wa...

    Authors: Mike Thomas, Tarita Murray-Thomas, Tao Fan, Tim Williams and Stephanie Taylor

    Citation: BMC Pulmonary Medicine 2010 10:29

    Content type: Research article

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  38. In chronic obstructive pulmonary disease (COPD), the response of the forced expiratory volume in 1 second (FEV1) after bronchodilator application is weak. Inspiratory parameters like the forced inspiratory vol...

    Authors: Frank J Visser, Sunil Ramlal, Ben Pelzer, PN Richard Dekhuijzen and Yvonne F Heijdra

    Citation: BMC Pulmonary Medicine 2010 10:28

    Content type: Research article

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  39. Injection drug use is associated with an increased risk of human immunodeficiency virus (HIV) infection and with obstructive lung diseases (OLD). Understanding how HIV and OLD may impact respiratory symptoms a...

    Authors: M Bradley Drummond, Gregory D Kirk, Erin P Ricketts, Meredith C McCormack, J Christian Hague, John F McDyer, Shruti H Mehta, Eric A Engels, Robert A Wise and Christian A Merlo

    Citation: BMC Pulmonary Medicine 2010 10:27

    Content type: Research article

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  40. Pulmonary fibrosis (PF) is a group of devastating and largely irreversible diseases. Phosphodiesterase (PDE) 4 is involved in the processes of remodeling and inflammation, which play key role in tissue fibrosi...

    Authors: Sergey Udalov, Rio Dumitrascu, Soni S Pullamsetti, Hamza M Al-tamari, Norbert Weissmann, Hossein A Ghofrani, Andreas Guenther, Robert Voswinckel, Werner Seeger, Friedrich Grimminger and Ralph T Schermuly

    Citation: BMC Pulmonary Medicine 2010 10:26

    Content type: Research article

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  41. Ventilator-induced lung injury (VILI) is a recognized complication of mechanical ventilation. Although the specific mechanism by which mechanical ventilation causes lung injury remains an active area of study,...

    Authors: Scott E Sinclair, Nayak L Polissar and William A Altemeier

    Citation: BMC Pulmonary Medicine 2010 10:25

    Content type: Research article

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  42. The aim is to assess the validity and reliability of transbronchial needle aspiration (TBNA) of mediastinal and hilar adenopathies and to evaluate factors predictive of TBNA outcome.

    Authors: Alberto Fernández-Villar, Maribel Botana, Virginia Leiro, Ana González, Cristina Represas and Alberto Ruano-Raviña

    Citation: BMC Pulmonary Medicine 2010 10:24

    Content type: Research article

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  43. 8-Isoprostane (8-IP) is a marker of lipid peroxidation. Elevated concentrations have been reported in BAL fluid and exhaled breath condensate (EBC) in sarcoidosis (S). To validate the prognostic value of this ...

    Authors: Wojciech J Piotrowski, Zofia Kurmanowska, Adam Antczak, Jerzy Marczak and Paweł Górski

    Citation: BMC Pulmonary Medicine 2010 10:23

    Content type: Research article

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  44. Liver dysfunction reflects the status of heart failure, with congestion and low perfusion of the liver serving as causative mechanisms. Previous studies demonstrated relationship between the results of liver f...

    Authors: Yasuko Takeda, Yutaka Takeda, Shigehiro Tomimoto, Tomomitsu Tani, Hitomi Narita and Genjiro Kimura

    Citation: BMC Pulmonary Medicine 2010 10:22

    Content type: Research article

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  45. A large number of studies have investigated the effects of high tidal volume ventilation in mouse models. In contrast data on very short term effects of low tidal volume ventilation are sparse. Therefore we in...

    Authors: Hans P Hauber, Dörte Karp, Torsten Goldmann, Ekkehard Vollmer and Peter Zabel

    Citation: BMC Pulmonary Medicine 2010 10:21

    Content type: Research article

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    The Erratum to this article has been published in BMC Pulmonary Medicine 2012 12:7

  46. While lipopolysaccharide (LPS) from Gram-negative bacteria has been shown to augment inflammation in ventilated lungs information on the effect of Gram-positive bacteria is lacking. Therefore the effect of LPS...

    Authors: Hans P Hauber, Dörte Karp, Torsten Goldmann, Ekkehard Vollmer and Peter Zabel

    Citation: BMC Pulmonary Medicine 2010 10:20

    Content type: Research article

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  47. Few studies have been carried out on acute effects of cement dust exposure. This study is conducted to investigate the associations between current "total" dust exposure and acute respiratory symptoms and resp...

    Authors: Zeyede K Zeleke, Bente E Moen and Magne Bråtveit

    Citation: BMC Pulmonary Medicine 2010 10:19

    Content type: Research article

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  48. Right ventricular dilatation in the setting of acute pulmonary embolism is associated with an adverse prognosis. Treatment with a pulmonary vasodilator has never been studied systematically. We evaluated the e...

    Authors: Albertus J Kooter, Richard G IJzerman, Otto Kamp, Anco B Boonstra and Yvo M Smulders

    Citation: BMC Pulmonary Medicine 2010 10:18

    Content type: Research article

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  49. Pulsus paradoxus estimated by dynamic change in area under the oximeter plethysmograph waveform (PEP) might provide a measure of acute asthma severity. Our primary objective was to determine how well PEP corre...

    Authors: Donald H Arnold, Cathy A Jenkins and Tina V Hartert

    Citation: BMC Pulmonary Medicine 2010 10:17

    Content type: Research article

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