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  1. Despite recommendations for outpatient management, low risk patients with lower respiratory tract infections (LRTIs) are often hospitalized. This survey analyzed perceptions of physicians, nurses, patients and...

    Authors: Claudia Baehni, Sabine Meier, Pamela Spreiter, Ursula Schild, Katharina Regez, Rita Bossart, Robert Thomann, Claudine Falconnier, Mirjam Christ-Crain, Sabina De Geest, Beat Müller and Philipp Schuetz

    Citation: BMC Pulmonary Medicine 2010 10:12

    Content type: Research article

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  2. Indacaterol is a novel, once-daily (o.d.) inhaled, long-acting β 2-agonist in development for chronic obstructive pulmonary disease (COPD). This 12-week, double-blind study compared the efficacy, safety, and tole...

    Authors: Gregory Feldman, Thomas Siler, Niyati Prasad, Damon Jack, Simon Piggott, Roger Owen, Mark Higgins and Benjamin Kramer

    Citation: BMC Pulmonary Medicine 2010 10:11

    Content type: Research article

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  3. Health status, dyspnea and psychological status are important clinical outcomes in chronic obstructive pulmonary disease (COPD). However, forced expiratory volume in one second (FEV1) measured by spirometry, the ...

    Authors: Akane Haruna, Toru Oga, Shigeo Muro, Tadashi Ohara, Susumu Sato, Satoshi Marumo, Daisuke Kinose, Kunihiko Terada, Michiyoshi Nishioka, Emiko Ogawa, Yuma Hoshino, Toyohiro Hirai, Kazuo Chin and Michiaki Mishima

    Citation: BMC Pulmonary Medicine 2010 10:10

    Content type: Research article

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  4. Heart failure (HF) and sleep apnoea (SA) association has been recognized but whether it results from confounding factors (hypertension, ischaemia, obesity) remains unclear.

    Authors: Susana Ferreira, Anabela Marinho, Marta Patacho, Elisabete Santa-Clara, Cristina Carrondo, João Winck and Paulo Bettencourt

    Citation: BMC Pulmonary Medicine 2010 10:9

    Content type: Research article

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  5. Pandemic Influenza A (H1N1) 2009 is a novel viral infection that emerged in March 2009. This is the first report addressing the clinical course of patients with cystic fibrosis (CF) and H1N1 infection.

    Authors: Megan W France, Szeanna Tai, Phillip J Masel, Vanessa L Moore, Tracy L McMahon, Alexander J Ritchie and Scott C Bell

    Citation: BMC Pulmonary Medicine 2010 10:8

    Content type: Research article

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  6. Previous health economic studies recommend either a dual screening strategy [tuberculin skin test (TST) followed by interferon-γ-release assay (IGRA)] or a single one [IGRA only] for latent tuberculosis infect...

    Authors: Anil Pooran, Helen Booth, Robert F Miller, Geoff Scott, Motasim Badri, Jim F Huggett, Graham Rook, Alimuddin Zumla and Keertan Dheda

    Citation: BMC Pulmonary Medicine 2010 10:7

    Content type: Research article

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  7. Preventing ventilator-associated lung injury (VALI) has become pivotal in mechanical ventilation of patients with acute lung injury (ALI) or its more severe form, acute respiratory distress syndrome (ARDS). In...

    Authors: Rogier M Determann, Annick ANM Royakkers, Jack J Haitsma, Haibo Zhang, Arthur S Slutsky, V Marco Ranieri and Marcus J Schultz

    Citation: BMC Pulmonary Medicine 2010 10:6

    Content type: Research article

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  8. Non-cystic fibrosis bronchiectasis is characterised by sputum production, exercise limitation and recurrent infections. Although pulmonary rehabilitation is advocated for this patient group, its effects are un...

    Authors: Annemarie L Lee, Nola Cecins, Catherine J Hill, Anne E Holland, Linda Rautela, Robert G Stirling, Phillip J Thompson, Christine F McDonald and Sue Jenkins

    Citation: BMC Pulmonary Medicine 2010 10:5

    Content type: Study protocol

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  9. Nitric oxide (NO) shows differing concentrations in lower and upper airways. Patients after total laryngectomy are the only individuals, in whom a complete separation of upper and lower airways is guaranteed. ...

    Authors: Matthias F Kramer, Bernhard Olzowy, Annette Bihler, Dorothea de la Motte, Dennis Nowak, Rudolf A Jörres and Holger Dressel

    Citation: BMC Pulmonary Medicine 2010 10:4

    Content type: Research article

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  10. IL-13 has been implicated in the development of airway inflammation and hyperresponsiveness. This study investigated the multiple-dose pharmacokinetics and safety profile of human anti-IL-13 antibody (CAT-354)...

    Authors: Dave Singh, Binita Kane, Nestor A Molfino, Raffaella Faggioni, Lorin Roskos and Ashley Woodcock

    Citation: BMC Pulmonary Medicine 2010 10:3

    Content type: Research article

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  11. Urinary incontinence (UI) is a distressing problem for older people. To investigate the relationship between UI and respiratory symptoms among middle-aged and older men, a community-based study was conducted i...

    Authors: Fumi Hirayama, Andy H Lee, Tetsuo Hiramatsu and Yoshimasa Tanikawa

    Citation: BMC Pulmonary Medicine 2010 10:2

    Content type: Research article

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  12. Poor adherence with prescribed asthma medication is a major barrier to positive treatment outcomes. This study was designed to determine the effect of a once-daily administration of mometasone furoate administ...

    Authors: David Price, Anne Robertson, Kevin Bullen, Cynthia Rand, Rob Horne and Heribert Staudinger

    Citation: BMC Pulmonary Medicine 2010 10:1

    Content type: Research article

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  13. Airway inflammation and airway hyperresponsiveness (AHR) are two characteristic features of asthma. Fractional exhaled nitric oxide (FENO) has shown good correlation with AHR in asthmatics. Less information is...

    Authors: Valérie Demange, Abraham Bohadana, Nicole Massin and Pascal Wild

    Citation: BMC Pulmonary Medicine 2009 9:53

    Content type: Research article

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  14. Early detection of exacerbations by COPD patients initiating prompt interventions has shown to be clinically relevant. Until now, research failed to identify the effectiveness of a written individualized Actio...

    Authors: Jaap CA Trappenburg, Lieselotte Koevoets, Gerdien H de Weert-van Oene, Evelyn M Monninkhof, Jean Bourbeau, Thierry Troosters, Theo JM Verheij, Jan-Willem J Lammers and Augustinus JP Schrijvers

    Citation: BMC Pulmonary Medicine 2009 9:52

    Content type: Study protocol

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  15. High levels of exhaled carbon monoxide (eCO) are a marker of airway or lung inflammation. We investigated whether hypo- or hyperventilation can affect measured values.

    Authors: Franco Cavaliere, Carmen Volpe, Riccardo Gargaruti, Andrea Poscia, Michele Di Donato, Giovanni Grieco and Umberto Moscato

    Citation: BMC Pulmonary Medicine 2009 9:51

    Content type: Research article

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  16. Spirometry is a cost-effective diagnostic tool for evaluation of lung function and for case-finding in a resource-limited setting. The acceptance of this test depends on the awareness of its indications and th...

    Authors: Olufemi O Desalu, Olusegun A Busari, Cajetan C Onyedum, Fatai K Salawu, Olusegun A Obateru, Kelechukwu C Nwogu and Alakija K Salami

    Citation: BMC Pulmonary Medicine 2009 9:50

    Content type: Research article

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  17. Despite consensus criteria, diagnosing acute lung injury, or its more severe form acute respiratory distress syndrome (ALI/ARDS) remains challenging. Adding objective measures, such as plasma levels of biologi...

    Authors: Rogier M Determann, Julian L Millo, Sam Waddy, Rene Lutter, Chris S Garrard and Marcus J Schultz

    Citation: BMC Pulmonary Medicine 2009 9:49

    Content type: Research article

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  18. The collection of exhaled breath condensate (EBC) is a suitable and non-invasive method for evaluation of airway inflammation. Several studies indicate that the composition of the condensate and the recovery o...

    Authors: Frank Hoffmeyer, Monika Raulf-Heimsoth, Volker Harth, Jürgen Bünger and Thomas Brüning

    Citation: BMC Pulmonary Medicine 2009 9:48

    Content type: Research article

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  19. Previous studies have shown conflicting results for the association between TLR4 polymorphism (Asp299Gly) and lung function. We investigated the influence of TLR4 Asp299Gly, a polymorphism, on lung function in...

    Authors: Punam Pahwa, Chandima P Karunanayake, Donna C Rennie, Yue Chen, David A Schwartz and James A Dosman

    Citation: BMC Pulmonary Medicine 2009 9:46

    Content type: Research article

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  20. To determine whether oral administration of geranylgeranylacetone (GGA), a nontoxic anti-ulcer drug that is an inducer of heat shock protein (HSP) 70, protects against drug-induced lung injury/fibrosis in vivo.

    Authors: Takayoshi Fujibayashi, Naozumi Hashimoto, Mayumi Jijiwa, Yoshinori Hasegawa, Toshihisa Kojima and Naoki Ishiguro

    Citation: BMC Pulmonary Medicine 2009 9:45

    Content type: Research article

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  21. Tigecycline, an expanded broad-spectrum glycylcycline, exhibits in vitro activity against many common pathogens associated with community-acquired pneumonia (CAP), as well as penetration into lung tissues that...

    Authors: Cristina Tanaseanu, Slobodan Milutinovic, Petre I Calistru, Janos Strausz, Marius Zolubas, Valeriy Chernyak, Nathalie Dartois, Nathalie Castaing, Hassan Gandjini and C Angel Cooper

    Citation: BMC Pulmonary Medicine 2009 9:44

    Content type: Research article

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  22. Asthma and COPD are major health problems and an extensive burden for the patient and the health care system. Patient education has been recommended, but the influence on knowledge and health outcomes is not f...

    Authors: Margareta Emtner, Anna Hedin, Mikael Andersson and Christer Janson

    Citation: BMC Pulmonary Medicine 2009 9:43

    Content type: Research article

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  23. Epidemiological research into the role of traffic pollution on chronic respiratory and allergic disease has focused primarily on children. Studies in adults, in particular those based on objective outcomes suc...

    Authors: Mar Pujades-Rodríguez, Tricia McKeever, Sarah Lewis, Duncan Whyatt, John Britton and Andrea Venn

    Citation: BMC Pulmonary Medicine 2009 9:42

    Content type: Research article

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  24. Lithuania is a country with a high incidence of tuberculosis (TB), despite a high coverage with bacille Calmette-Guerin (BCG) vaccination. Until now the only method used to detect latent TB infection was the t...

    Authors: Edita Hansted, Angele Andriuskeviciene, Raimundas Sakalauskas, Rimantas Kevalas and Brigita Sitkauskiene

    Citation: BMC Pulmonary Medicine 2009 9:41

    Content type: Research article

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  25. Solitary endobronchial papillomas (SEP) are rare tumors and most of them are described by case report. A misdiagnosis is common with viral related papillomas. A histopathological classification has recently pe...

    Authors: Fabrice Paganin, Martine Prevot, Jean Baptiste Noel, Marie Frejeville, Claude Arvin-Berod and Arnaud Bourdin

    Citation: BMC Pulmonary Medicine 2009 9:40

    Content type: Case report

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  26. The lung consists of at least seven compartments with relevance to immune reactions. Compartment 1 - the bronchoalveolar lavage (BAL), which represents the cells of the bronchoalveolar space: From a diagnostic...

    Authors: Thomas Tschernig and Reinhard Pabst

    Citation: BMC Pulmonary Medicine 2009 9:39

    Content type: Commentary

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  27. Multicentre drug use evaluations are described in the literature infrequently and usually publish only the results. The purpose of this paper is to describe the experience of Queensland hospitals participating...

    Authors: Lisa K Pulver, Susan E Tett and Judith Coombes

    Citation: BMC Pulmonary Medicine 2009 9:38

    Content type: Correspondence

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  28. There is a substantial body of evidence on the efficacy of yoga in the management of bronchial asthma. Many studies have reported, as the effects of yoga on bronchial asthma, significant improvements in pulmon...

    Authors: Ramaprabhu Vempati, Ramesh Lal Bijlani and Kishore Kumar Deepak

    Citation: BMC Pulmonary Medicine 2009 9:37

    Content type: Research article

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  29. Heart surgery is associated with an occurrence of pulmonary complications. The aim of this study was to determine whether pre-surgery respiratory physiotherapy reduces the incidence of post-surgery pulmonary c...

    Authors: Isabel Yánez-Brage, Salvador Pita-Fernández, Alberto Juffé-Stein, Ursicino Martínez-González, Sonia Pértega-Díaz and Ángeles Mauleón-García

    Citation: BMC Pulmonary Medicine 2009 9:36

    Content type: Research article

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  30. Cardiac Troponin T (cTnT) elevation during exacerbations of chronic obstructive pulmonary disease (COPD) is associated with increased mortality the first year after hospital discharge. The factors associated w...

    Authors: Pål H Brekke, Torbjørn Omland, Stein Harald Holmedal, Pål Smith and Vidar Søyseth

    Citation: BMC Pulmonary Medicine 2009 9:35

    Content type: Research article

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  31. In asthma interleukin (IL)-13 is increased in the airway compared with non-asthmatic eosinophilic bronchitis. Whether this differential expression is specific to the airway or is more generalised is uncertain.

    Authors: Salman Siddiqui, Glenn Cruse, Susan Mckenna, William Monteiro, Vijay Mistry, Andrew Wardlaw and Christopher Brightling

    Citation: BMC Pulmonary Medicine 2009 9:34

    Content type: Research article

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  32. N-chlorotaurine, a long-lived oxidant produced by human leukocytes, can be applied in human medicine as an endogenous antiseptic. Its antimicrobial activity can be enhanced by ammonium chloride. This study was...

    Authors: Ralf Geiger, Benedikt Treml, Anna Pinna, Linn Barnickel, Harald Prossliner, Hannes Reinstadler, Michael Pilch, Maria Hauer, Christoph Walther, Hans-Jörg Steiner, Thomas Giese, Andreas Wemhöner, Sabine Scholl-Bürgi, Waldemar Gottardi, Roland Arnitz, Consolato Sergi…

    Citation: BMC Pulmonary Medicine 2009 9:33

    Content type: Research article

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  33. Statins have anti-inflammatory and immunomodulating properties which could possibly influence inflammatory airways disease. We assessed evidence for disease modifying effects of statin treatment in patients wi...

    Authors: Claudia C Dobler, Keith K Wong and Guy B Marks

    Citation: BMC Pulmonary Medicine 2009 9:32

    Content type: Research article

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  34. To evaluate the sensitivity, specificity and predictive values of spirometry for the diagnosis of chronic obstructive pulmonary disease (COPD) and asthma in patients suspected of suffering from an obstructive ...

    Authors: Antonius Schneider, Lena Gindner, Lisa Tilemann, Tjard Schermer, Geert-Jan Dinant, Franz Joachim Meyer and Joachim Szecsenyi

    Citation: BMC Pulmonary Medicine 2009 9:31

    Content type: Research article

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  35. Due to large-scale destruction, changes in membrane diffusion (Dm) may occur in cystic fibrosis (CF), in correspondence to alterations observed by computed tomography (CT). Dm can be easily quantified via the ...

    Authors: Holger Dressel, Laura Filser, Rainald Fischer, Katharina Marten, Ullrich Müller-Lisse, Dorothea de la Motte, Dennis Nowak, Rudolf M Huber and Rudolf A Jörres

    Citation: BMC Pulmonary Medicine 2009 9:30

    Content type: Research article

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  36. Exercise-related respiratory symptoms in the diagnosis of exercise-induced bronchoconstriction (EIB) have poor predictive value. The aim of this study was to evaluate how athletes presenting with these symptom...

    Authors: James H Hull, Peter J Hull, Jonathan P Parsons, John W Dickinson and Les Ansley

    Citation: BMC Pulmonary Medicine 2009 9:29

    Content type: Research article

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  37. Increased respiratory rate (tachypnea) is frequently observed as a clinical sign of influenza pneumonia in pediatric patients admitted to the hospital. We previously demonstrated that influenza infection of ad...

    Authors: Elman L Trias, Arash Hassantoufighi, Gregory A Prince and Maryna C Eichelberger

    Citation: BMC Pulmonary Medicine 2009 9:28

    Content type: Research article

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  38. SCF (stem cell factor) is a pleiotropic cytokine exerting its role at different stages of bone marrow development and affecting eosinophil activation, mast cells and basophil chemotaxis and survival. The aim o...

    Authors: Joanna S Makowska, Malgorzata Cieslak and Marek L Kowalski

    Citation: BMC Pulmonary Medicine 2009 9:27

    Content type: Research article

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  39. Pulmonary rehabilitation is known to be a beneficial treatment for COPD patients. To date, however, there is no agreement for how long a rehabilitation program should be implemented. In addition, current views...

    Authors: David Stav, Meir Raz and Isaac Shpirer

    Citation: BMC Pulmonary Medicine 2009 9:26

    Content type: Research article

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  40. Asthma is associated with enormous healthcare expenditures that include both direct and indirect costs. It is also associated with the loss of future potential earnings related to both morbidity and mortality....

    Authors: Katayoun Bahadori, Mary M Doyle-Waters, Carlo Marra, Larry Lynd, Kadria Alasaly, John Swiston and Js Mark FitzGerald

    Citation: BMC Pulmonary Medicine 2009 9:24

    Content type: Research article

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  41. Incense burning has been reported to adversely affect respiratory health. The aim of this study was to explore whether exposure to bakhour contributes to the prevalence of asthma and/or triggers its symptoms i...

    Authors: Omar A Al-Rawas, Abdullah A Al-Maniri and Bazdawi M Al-Riyami

    Citation: BMC Pulmonary Medicine 2009 9:23

    Content type: Research article

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  42. Herpes simplex virus type-1 (HSV-1) has been described to cause respiratory tract infections in critically ill patients or in individuals that are immunocompromised. It is a continuing matter of debate under w...

    Authors: Matthias N Witt, Gerald S Braun, Stephan Ihrler and Holger Schmid

    Citation: BMC Pulmonary Medicine 2009 9:22

    Content type: Research article

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  43. Interferon gamma release assays, including the QuantiFERON® TB Gold In Tube (QFT) have been shown to be accurate in diagnosing Mycobacterium tuberculosis infection. These assays however, do not discriminate betwe...

    Authors: Novel N Chegou, Gillian F Black, Martin Kidd, Paul D van Helden and Gerhard Walzl

    Citation: BMC Pulmonary Medicine 2009 9:21

    Content type: Research article

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  44. Recombinant human activated protein C (rhAPC) is associated with improved survival in high-risk patients with severe sepsis; however, the effects of both lipopolysaccharide (LPS) and rhAPC on the bronchoalveol...

    Authors: Russell P Bowler, Nichole Reisdorph, Richard Reisdorph and Edward Abraham

    Citation: BMC Pulmonary Medicine 2009 9:20

    Content type: Research article

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  45. While modulation of the serotonin transporter (5HTT) has shown to be a risk factor for pulmonary arterial hypertension for almost 40 years, there is a lack of in vivo data about the broad molecular effects of ...

    Authors: Daniel Crona, Julie Harral, Serge Adnot, Saadia Eddahibi and James West

    Citation: BMC Pulmonary Medicine 2009 9:19

    Content type: Research article

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  46. The association between systemic sclerosis and pulmonary arterial hypertension (PAH) is well recognized. Vascular endothelial growth factor (VEGF) has been reported to play an important role in pulmonary hyper...

    Authors: Andriana I Papaioannou, Epaminondas Zakynthinos, Konstantinos Kostikas, Theodoros Kiropoulos, Angela Koutsokera, Athanasios Ziogas, Athanasios Koutroumpas, Lazaros Sakkas, Konstantinos I Gourgoulianis and Zoe D Daniil

    Citation: BMC Pulmonary Medicine 2009 9:18

    Content type: Research article

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  47. The incidence and morbidity of wheezing illnesses and childhood asthma is especially high in poor urban areas. This paper describes the study design, methods, and population of the Urban Environment and Childh...

    Authors: James E Gern, Cynthia M Visness, Peter J Gergen, Robert A Wood, Gordon R Bloomberg, George T O'Connor, Meyer Kattan, Hugh A Sampson, Frank R Witter, Megan T Sandel, Wayne G Shreffler, Rosalind J Wright, Samuel J Arbes Jr and William W Busse

    Citation: BMC Pulmonary Medicine 2009 9:17

    Content type: Study protocol

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  48. Sputum smear microscopy is the standard diagnostic method for detection of smear positive pulmonary tuberculosis (TB). Insufficient quality of sputum might result in missing cases. In this study we aimed at as...

    Authors: Mateus Sakundarno, Nurjazuli Nurjazuli, Sutopo Patria Jati, Retna Sariningdyah, Sumarsono Purwadi, Bachti Alisjahbana and Marieke J van der Werf

    Citation: BMC Pulmonary Medicine 2009 9:16

    Content type: Research article

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