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  1. We studied the value of routine biochemical variables albumin, C-reactive protein (CRP) and lactate dehydrogenase (LDH) to improve prediction and monitoring of acute respiratory distress syndrome (ARDS) severi...

    Authors: Sandra H Hoeboer, Heleen M Oudemans-van Straaten and AB Johan Groeneveld
    Citation: BMC Pulmonary Medicine 2015 15:22
  2. To evaluate the factors affecting the maximum standardized uptake value (SUVmax) of metastatic lymph nodes in different histological types of non-small cell lung cancer (NSCLC) on integrated positron emission ...

    Authors: Yuehong Wang, Shanni Ma, Mengjie Dong, Yake Yao, Kanfeng Liu and Jianying Zhou
    Citation: BMC Pulmonary Medicine 2015 15:20
  3. Secretory leukocyte protease inhibitor (SLPI) is a protein with anti-protease and antimicrobial properties that is constitutively secreted from the airway epithelium. The importance of maintaining a balance be...

    Authors: Lisa I Påhlman, Annika Jögi, Magnus Gram, Michiko Mori and Arne Egesten
    Citation: BMC Pulmonary Medicine 2015 15:19
  4. Argan is now used worldwide in numerous cosmetic products. Nine workers from a cosmetic factory were examined in our occupational medicine department, following the diagnosis of a case of hypersensitivity pneu...

    Authors: Christophe Paris, Fabrice Herin, Gabriel Reboux, Emmanuelle Penven, Coralie Barrera, Cécile Guidat and Isabelle Thaon
    Citation: BMC Pulmonary Medicine 2015 15:18
  5. Asthma is the most common chronic condition of childhood and disproportionately affects inner-city minority children. Low rates of asthma preventer medication adherence is a major contributor to poor asthma co...

    Authors: John M Wiecha, William G Adams, Denis Rybin, Maria Rizzodepaoli, Jeremy Keller and Jayanti M Clay
    Citation: BMC Pulmonary Medicine 2015 15:17
  6. The prevalence of diagnosed chronic obstructive pulmonary disease (COPD) in the UK is 1.8%, although it is estimated that this represents less than half of the total disease in the population as much remains u...

    Authors: Manbinder S Sidhu, Amanda Daley, Rachel Jordan, Peter A Coventry, Carl Heneghan, Sue Jowett, Sally Singh, Jennifer Marsh, Peymane Adab, Jinu Varghese, David Nunan, Amy Blakemore, Jenny Stevens, Lee Dowson, David Fitzmaurice and Kate Jolly
    Citation: BMC Pulmonary Medicine 2015 15:16
  7. Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) has an extremely poor prognosis and there is currently no effective treatment for this condition. Direct hemoperfusion with a polymyxin B-immobilize...

    Authors: Noriyuki Enomoto, Masashi Mikamo, Yoshiyuki Oyama, Masato Kono, Dai Hashimoto, Tomoyuki Fujisawa, Naoki Inui, Yutaro Nakamura, Hideo Yasuda, Akihiko Kato, Soichiro Mimuro, Matsuyuki Doi, Shigehito Sato and Takafumi Suda
    Citation: BMC Pulmonary Medicine 2015 15:15
  8. Interleukin-27 (IL-27) is a multifunctional cytokine with both pro-inflammatory and immunoregulatory functions. At present, the role of IL-27 in pulmonary fibrosis remains unknown.

    Authors: Zhaoxing Dong, Xin Lu, Yanni Yang, Tao Zhang, Yongxia Li, Yanlin Chai, Wen Lei, Changbo Li, Li Ai and Wenlin Tai
    Citation: BMC Pulmonary Medicine 2015 15:13
  9. Asthma is characterized by airway hyper-responsiveness and variable airflow obstruction, in part as a consequence of hyper-contractile airway smooth muscle, which persists in primary cell culture. One potentia...

    Authors: David Sweeney, Fay Hollins, Edith Gomez, Rajendra Mistry, Ruth Saunders, Robert Alfred John Challiss and Christopher Edward Brightling
    Citation: BMC Pulmonary Medicine 2015 15:12
  10. Patients with precapillary pulmonary hypertension (PH) have been reported to suffer from poor sleep quality, however, if this is related to physical exercise performance has not yet been thoroughly investigated.

    Authors: Henning Tiede, Janet Rorzyczka, Rio Dumitrascu, Michael Belly, Frank Reichenberger, Hossein Ardeschir Ghofrani, Werner Seeger, Jörg Heitmann and Richard Schulz
    Citation: BMC Pulmonary Medicine 2015 15:11
  11. Chronic respiratory diseases are a significant cause of morbidity and mortality worldwide. We sought to evaluate the impact of asthma, chronic bronchitis and allergic rhinitis on all-cause hospitalizations and...

    Authors: Simone Accordini, Angelo Guido Corsico, Lucia Calciano, Roberto Bono, Isa Cerveri, Alessandro Fois, Pietro Pirina, Roberta Tassinari, Giuseppe Verlato and Roberto de Marco
    Citation: BMC Pulmonary Medicine 2015 15:10
  12. GATA-2 transcription factor deficiency has recently been described in patients with a propensity towards myeloid malignancy associated with other highly variable phenotypic features: chronic leukocytopenias (d...

    Authors: Tamara Svobodova, Ester Mejstrikova, Ulrich Salzer, Martina Sukova, Petr Hubacek, Radoslav Matej, Martina Vasakova, Ludmila Hornofova, Marcela Dvorakova, Eva Fronkova, Felix Votava, Tomas Freiberger, Petr Pohunek, Jan Stary and Ales Janda
    Citation: BMC Pulmonary Medicine 2015 15:8
  13. The lectin-like domain of TNF-α can be mimicked by synthetic TIP peptides and represents an innovative pharmacologic option to treat edematous respiratory failure. TIP inhalation was shown to reduce pulmonary ...

    Authors: Erik K Hartmann, Alexander Ziebart, Rainer Thomas, Tanghua Liu, Arno Schad, Martha Tews, Bernd Moosmann, Jens Kamuf, Bastian Duenges, Serge C Thal and Matthias David
    Citation: BMC Pulmonary Medicine 2015 15:7
  14. Antibiotic-resistant strains of pathogenic bacteria are increasingly prevalent in hospitals and the community. Acute exacerbations of COPD (AE-COPD) often result in administration of antibiotics although more ...

    Authors: Gernot G U Rohde, Armin Koch and Tobias Welte
    Citation: BMC Pulmonary Medicine 2015 15:5
  15. With the goal of reducing exposure to secondhand smoke, the state of Minnesota (MN), enacted a smoke-free law (i.e., Freedom to Breathe Act) in all workplaces, restaurants, and bars in 2007. This retrospective...

    Authors: Ivana T Croghan, Jon O Ebbert, J Taylor Hays, Darrell R Schroeder, Alanna M Chamberlain, Véronique L Roger and Richard D Hurt
    Citation: BMC Pulmonary Medicine 2015 15:6
  16. Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD.

    Authors: Eva Balcells, Elena Gimeno-Santos, Jordi de Batlle, Maria Antonia Ramon, Esther Rodríguez, Marta Benet, Eva Farrero, Antoni Ferrer, Stefano Guerra, Jaume Ferrer, Jaume Sauleda, Joan A Barberà, Àlvar Agustí, Robert Rodriguez-Roisin, Joaquim Gea, Josep M Antó…
    Citation: BMC Pulmonary Medicine 2015 15:4
  17. In recent years, patients with cystic fibrosis (CF) have tended to experience a longer life expectancy and higher quality of life. In this context, the aim of the present study was to evaluate and compare the ...

    Authors: Fernando Augusto de Lima Marson, Tais Daiene Russo Hortencio, Katia Cristina Alberto Aguiar and Jose Dirceu Ribeiro
    Citation: BMC Pulmonary Medicine 2015 15:3
  18. A variety of large randomized controlled trials (RCT’s) evaluating pharmacotherapy in chronic obstructive pulmonary disease (COPD) patients does exist. One of the drugs that has been tested is the new long-act...

    Authors: Peter Kardos, Claus Vogelmeier, Roland Buhl, Carl-Peter Criée and Heinrich Worth
    Citation: BMC Pulmonary Medicine 2015 15:2
  19. YKL-40 is also called chitinase-3-like-1 (CHI3L1) protein and may be a marker for asthma. The aims of the present study were to investigate whether serum YKL-40 levels are stable or decreased in patients with ...

    Authors: Tianwen Lai, Min Chen, Zaichun Deng, Yingying Lǚ, Dong Wu, Dongming Li and Bin Wu
    Citation: BMC Pulmonary Medicine 2015 15:1
  20. This study evaluated the effects of aclidinium bromide, a long-acting muscarinic antagonist indicated for maintenance treatment of chronic obstructive pulmonary disease (COPD), on exercise endurance, dyspnea, ...

    Authors: Kai M Beeh, Henrik Watz, Luis Puente-Maestu, Luis de Teresa, Diana Jarreta, Cynthia Caracta, Esther Garcia Gil and Helgo Magnussen
    Citation: BMC Pulmonary Medicine 2014 14:209
  21. Adiposity has been linked to both higher risk of asthma and reduced lung function. The effects of adiposity on asthma may depend on both atopic status and gender, while the relationship is less clear with resp...

    Authors: Runa V Fenger, Arturo Gonzalez-Quintela, Carmen Vidal, Lise-Lotte Husemoen, Tea Skaaby, Betina H Thuesen, Mette Aadahl, Flemming Madsen and Allan Linneberg
    Citation: BMC Pulmonary Medicine 2014 14:208
  22. The association between impaired lung function and cardiovascular disease (CVD) risk factors has been shown in adults. However, there is little evidence of such an association in young adults, particularly fro...

    Authors: Vanessa Garcia-Larsen, Patricia Bustos, Hugo Amigo, James Potts and Roberto J Rona
    Citation: BMC Pulmonary Medicine 2014 14:206
  23. Epidemiological studies report high rates of depression among patients with cystic fibrosis (CF). Assuming a causal relationship between depression and the progression of CF, our hypothesis is that elevated sy...

    Authors: Astrid Fidika, Marion Herle and Lutz Goldbeck
    Citation: BMC Pulmonary Medicine 2014 14:205
  24. In a previous study, exhaled carbon monoxide (eCO) has been assessed in healthy non-smokers with a photo acoustic spectrometer Brüel&Kjær 1312. Unexpectedly, values were higher than those reported in literatur...

    Authors: Umberto Moscato, Andrea Poscia, Riccardo Gargaruti, Giovanni Capelli and Franco Cavaliere
    Citation: BMC Pulmonary Medicine 2014 14:204
  25. Community-acquired pneumonia (CAP) is a common cause of patient hospitalization and death, and its burden on the healthcare system is increasing in aging societies. Here, we develop and internally validate ris...

    Authors: Hironori Uematsu, Susumu Kunisawa, Noriko Sasaki, Hiroshi Ikai and Yuichi Imanaka
    Citation: BMC Pulmonary Medicine 2014 14:203
  26. Electronic noses are composites of nanosensor arrays. Numerous studies showed their potential to detect lung cancer from breath samples by analysing exhaled volatile compound pattern (“breathprint”). Expirator...

    Authors: Andras Bikov, Marton Hernadi, Beata Zita Korosi, Laszlo Kunos, Gabriella Zsamboki, Zoltan Sutto, Adam Domonkos Tarnoki, David Laszlo Tarnoki, Gyorgy Losonczy and Ildiko Horvath
    Citation: BMC Pulmonary Medicine 2014 14:202
  27. Tracheostomy is one of the most common surgical procedures performed in critical care patient management; more specifically, ventilation through tracheal cannula allows removal of the endotracheal tube (ETT). ...

    Authors: Pierachille Santus, Andrea Gramegna, Dejan Radovanovic, Rita Raccanelli, Vincenzo Valenti, Dimitri Rabbiosi, Michele Vitacca and Stefano Nava
    Citation: BMC Pulmonary Medicine 2014 14:201
  28. The prognosis of patients with suspected pulmonary embolism (PE) in whom PE has been ruled out (RPE) is unclear. We aimed to evaluate survival and diagnosis of new cancer in suspected PE patients at follow up.

    Authors: Fernando Javier Vazquez, María Lourdes Posadas-Martínez, Fernán González Bernaldo de Quirós and Diego Hernan Giunta
    Citation: BMC Pulmonary Medicine 2014 14:200
  29. There is no consensus regarding obesity repercussions for lung function in children and adolescents. Therefore, the aim of the study was to determine whether obesity is associated with poor physical conditioni...

    Authors: Mariana Simões Ferreira, Roberto Teixeira Mendes, Fernando Augusto de Lima Marson, Mariana Porto Zambon, Ilma Aparecida Paschoal, Adyleia Aparecida Dalbo Contrera Toro, Silvana Dalge Severino, Maria Ângela Gonçalves de Oliveira Ribeiro and José Dirceu Ribeiro
    Citation: BMC Pulmonary Medicine 2014 14:199
  30. The classic sweat test (CST) is the golden standard for cystic fibrosis (CF) diagnosis. Then, our aim was compare the production and volume of sweat, and side effects caused by pulsed direct current (PDC) and ...

    Authors: Carla Cristina Souza Gomez, Maria de Fatima Servidoni, Fernando Augusto de Lima Marson, Paulo Jose Coelho Canavezi, Adriana Mendes Vinagre, Eduardo Tavares Costa, Antonio Fernando Ribeiro, Maria Angela Gonçalves de Oliveira Ribeiro, Adyleia Aparecida Dalbo Contrera Toro, Celia Regina Pavan, Michelle Vivine Sá dos Santos Rondon, Sonia Leticia Silva Lorena, Francisco Ubaldi Vieria Junior and Jose Dirceu Ribeiro
    Citation: BMC Pulmonary Medicine 2014 14:198
  31. Late prognosis of Community-Acquired Pneumonia (CAP) patients is related to cardiovascular events. Persistence of inflammation-related markers, defined by high circulatory levels of interleukin 6 and 10 (IL-6/...

    Authors: Olga Rajas, Mara Ortega-Gómez, José María Galván Román, José Curbelo, Guillermo Fernández Jiménez, Lorena Vega Piris, Francisco Rodríguez Salvanes, Belén Arnalich, Sergio Luquero Bueno, Ana Díaz López, Hortensia de la Fuente, Carmen Suárez, Julio Ancochea and Javier Aspa
    Citation: BMC Pulmonary Medicine 2014 14:197
  32. Surfactant proteins SP-A and SP-D are useful biomarkers in diagnosis, monitoring, and prognosis of idiopathic pulmonary fibrosis (IPF). Despite their high structural homology, their serum concentrations often ...

    Authors: Hirotaka Nishikiori, Hirofumi Chiba, Shigeru Ariki, Koji Kuronuma, Mitsuo Otsuka, Masanori Shiratori, Kimiyuki Ikeda, Atsushi Watanabe, Yoshio Kuroki and Hiroki Takahashi
    Citation: BMC Pulmonary Medicine 2014 14:196
  33. Evidence suggests that there is an association between chronic obstructive pulmonary disease (COPD) and coronary heart disease (CHD). An important etiological link between COPD and CHD may be an underlying sys...

    Authors: Donna R Parker, Jonathan Liu, Mary B Roberts and Charles B Eaton
    Citation: BMC Pulmonary Medicine 2014 14:195
  34. To evaluate noninvasive ventilation (NIV) in diffuse interstitial lung diseases (DILD) patients with acute respiratory failure (ARF) according to baseline radiological patterns and the etiology of ARF.

    Authors: Stefano Aliberti, Grazia Messinesi, Silvia Gamberini, Sveva Maggiolini, Dina Visca, Vanni Galavotti, Fabio Giuliani, Roberto Cosentini, Anna Maria Brambilla, Francesco Blasi, Raffaele Scala, Mauro Carone, Francesca Luisi, Sergio Harari, Antonio Voza, Antonio Esquinas…
    Citation: BMC Pulmonary Medicine 2014 14:194
  35. The COPD Assessment Test (CAT™) is a new questionnaire that has been developed recently for measuring the COPD patient’s health status. It is known to have a good correlation with disease specific health statu...

    Authors: Chaicharn Pothirat, Sumalee Kiatboonsri and Charoen Chuchottaworn
    Citation: BMC Pulmonary Medicine 2014 14:193
  36. Non-small cell lung cancer (NSCLC) imposes a substantial burden on patients, health care systems and society due to increasing incidence and poor survival rates. In recent years, advances in the treatment of m...

    Authors: Ansgar Lange, Anne Prenzler, Martin Frank, Heiko Golpon, Tobias Welte and J-Matthias von der Schulenburg
    Citation: BMC Pulmonary Medicine 2014 14:192
  37. A subset of severe asthma patients has fixed airways obstruction, which is characterized by incomplete reversibility to bronchodilator challenge. We aimed to elucidate the factors associated with fixed airways...

    Authors: Anthony Chau Ang Yii, Gan Liang Tan, Keng Leong Tan, Therese Sophie Lapperre and Mariko Siyue Koh
    Citation: BMC Pulmonary Medicine 2014 14:191
  38. An innovative approach to lung volume reduction (LVR) for emphysema is introduced in the design of the Sequential Segmental Treatment of Emphysema with Upper Lobe Predominance (STEP-UP) trial where vapour abla...

    Authors: Arschang Valipour, Felix JF Herth, Ralf Eberhardt, Pallav L Shah, Avina Gupta, Robert Barry, Erik Henne, Sourish Bandyopadhyay and Greg Snell
    Citation: BMC Pulmonary Medicine 2014 14:190
  39. The use of computerized clinical decision support systems may improve the diagnosis and ongoing management of chronic diseases, which requires recurrent visits to multiple health professionals, disease and med...

    Authors: Mariam Fathima, David Peiris, Pradnya Naik-Panvelkar, Bandana Saini and Carol Lyn Armour
    Citation: BMC Pulmonary Medicine 2014 14:189
  40. To evaluate the compliance, benefits and side effects associated with continuous positive airway pressure (CPAP) therapy among Pakistani patients treated for obstructive sleep apnea (OSA) in private sector.

    Authors: Syed Fayyaz Hussain, Muhammad Irfan, Zeeshan Waheed, Naveen Alam, Saba Mansoor and Muhammad Islam
    Citation: BMC Pulmonary Medicine 2014 14:188
  41. Increased small airway resistance and decreased lung elasticity contribute to the airflow limitation in chronic obstructive pulmonary disease (COPD). The lesion that corresponds to loss of lung elasticity is e...

    Authors: Sergey Stepaniants, I-Ming Wang, Yves Boie, James Mortimer, Brian Kennedy, Mark Elliott, Shizu Hayashi, Honglin Luo, Jerry Wong, Leanna Loy, Silvija Coulter, Christopher J Roberts, James C Hogg, Don D Sin, Gary O’Neill, Michael Crackower…
    Citation: BMC Pulmonary Medicine 2014 14:187
  42. Depression is a common comorbidity among patients with Chronic Obstructive Pulmonary Disease (COPD) and has a significant impact on the course of the disease. The aim of this study is to determine association ...

    Authors: José Laerte R Silva Júnior, Marcus Barreto Conde, Krislainy de Sousa Corrêa, Christina da Silva, Leonardo da Silva Prestes and Marcelo Fouad Rabahi
    Citation: BMC Pulmonary Medicine 2014 14:186
  43. Toxoplasmosis is one of the most common human zoonosis, and is generally benign in most of the individuals. Pulmonary involvement is common in immunocompromised subjects, but very rare in immunocompetents and ...

    Authors: Karina de Souza Giassi, Andre Nathan Costa, Andre Apanavicius, Fernando Bin Teixeira, Caio Julio Cesar Fernandes, Alfredo Salim Helito and Ronaldo Adib Kairalla
    Citation: BMC Pulmonary Medicine 2014 14:185
  44. This paper reviews evidence and quality of Systematic Reviews (SRs) on the effects of breathing control exercises (BCEs) and respiratory muscle training (RMT) on breathlessness/dyspnea and other symptoms, and ...

    Authors: Christine Råheim Borge, Kåre Birger Hagen, Anne Marit Mengshoel, Ernst Omenaas, Torbjørn Moum and Astrid Klopstad Wahl
    Citation: BMC Pulmonary Medicine 2014 14:184
  45. The safety and efficiency of gene therapies for cystic fibrosis (CF) need to be assessed in pre-clinical models. Using the normal ferret, this study sought to determine whether ferret airway epithelia could be...

    Authors: Patricia Cmielewski, Nigel Farrow, Martin Donnelley, Chantelle McIntyre, Jahan Penny-Dimri, Tim Kuchel and David Parsons
    Citation: BMC Pulmonary Medicine 2014 14:183
  46. Authors: Victoria M Lord, Victoria J Hume, Julia L Kelly, Phoene Cave, Judith Silver, Maya Waldman, Chris White, Cayley Smith, Rebecca Tanner, Melissa Sanchez, William D-C Man, Michael I Polkey and Nicholas S Hopkinson
    Citation: BMC Pulmonary Medicine 2014 14:181

    The original article was published in BMC Pulmonary Medicine 2012 12:69

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