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  1. The recent increase in childhood asthma has been a puzzling one. Recent views focus on the role of infection in the education of the immune system of young children. However, this so called hygiene hypothesis ...

    Authors: Wasim Maziak
    Citation: BMC Pulmonary Medicine 2005 5:5
  2. Multiple studies have linked fungal exposure to asthma, but the link to severe asthma is controversial. We studied the relationship between asthma severity and immediate type hypersensitivity to mold (fungal) ...

    Authors: B Ronan O'Driscoll, Linda C Hopkinson and David W Denning
    Citation: BMC Pulmonary Medicine 2005 5:4
  3. Whether inhaled corticosteroids suppress airway inflammation in chronic obstructive pulmonary disease (COPD) remains controversial. We sought to determine the effects of inhaled corticosteroids on sputum indic...

    Authors: Wen Qi Gan, SF Paul Man and Don D Sin
    Citation: BMC Pulmonary Medicine 2005 5:3
  4. Asthma is a complex genetic disease with more than 20 genome-wide scans conducted so far. Regions on almost every chromosome have been linked to asthma and several genes have been associated. However, most of ...

    Authors: Janine Altmüller, Corinna Seidel, Young-Ae Lee, Sabine Loesgen, Dieter Bulle, Frank Friedrichs, Heidemarie Jellouschek, Julika Kelber, Angela Keller, Antje Schuster, Michael Silbermann, Wolfgang Wahlen, Peter Wolff, Gerhard Schlenvoigt, Franz Rüschendorf, Peter Nürnberg…
    Citation: BMC Pulmonary Medicine 2005 5:1
  5. Prophylactic treatment with N-acetylcysteine (NAC) for 3 months or more is associated with a reduction in the frequency of exacerbations of chronic obstructive pulmonary disease (COPD). This raises the questio...

    Authors: Peter N Black, Althea Morgan-Day, Tracey E McMillan, Phillippa J Poole and Robert P Young
    Citation: BMC Pulmonary Medicine 2004 4:13
  6. Patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) commonly require hospitalization and admission to intensive care unit (ICU). It is useful to identify patients at the time of ad...

    Authors: GC Khilnani, Amit Banga and SK Sharma
    Citation: BMC Pulmonary Medicine 2004 4:12
  7. A number of subjects, especially the very young and the elderly, are unable to cooperate and to perform forced expiratory manoeuvres in the evaluation of bronchial hyperresponsiveness (BHR). The objective of o...

    Authors: Panagiotis Panagou, Ioannis Kottakis, Argyris Tzouvelekis, Stavros Anevlavis and Demosthenes Bouros
    Citation: BMC Pulmonary Medicine 2004 4:11
  8. Many trials of nebulized therapy have used nebulized saline as a "placebo". However, nebulized isotonic saline is sometimes used to assist sputum expectoration and relieve breathlessness in COPD patients. We d...

    Authors: Shahina Y Khan and B Ronan O'Driscoll
    Citation: BMC Pulmonary Medicine 2004 4:9
  9. Non-invasive monitoring of respiratory muscle function is an area of increasing research interest, resulting in the appearance of new monitoring devices, one of these being piezoelectric contact sensors. The p...

    Authors: José Antonio Fiz, Raimon Jané, Abel Torres, Josep Morera, Batxi Galdiz, Joaquín Gea and Alejandro Grassino
    Citation: BMC Pulmonary Medicine 2004 4:8
  10. The long acting β2-agonists, salmeterol and formoterol, have been recommended, by some, as first line treatment of stable chronic obstructive pulmonary disease (COPD). We reviewed evidence of efficacy and safe...

    Authors: Don Husereau, Vijay Shukla, Michel Boucher, Shaila Mensinkai and Robert Dales
    Citation: BMC Pulmonary Medicine 2004 4:7
  11. The predictive role of many cytokines has not been well defined in Acute Respiratory Distress Syndrome (ARDS).

    Authors: Demosthenes Bouros, Michael G Alexandrakis, Katerina M Antoniou, Panagiotis Agouridakis, Ioannis Pneumatikos, Stavros Anevlavis, Athanasia Pataka, George Patlakas, Nikolaos Karkavitsas and Despina Kyriakou
    Citation: BMC Pulmonary Medicine 2004 4:6
  12. Physical exercise has become a cornerstone of management of chronic obstructive pulmonary disease (COPD) because it leads to clinically relevant improvements of exercise capacity and health-related quality of ...

    Authors: Milo A Puhan, Gilbert Büsching, Evelien vanOort, Christian Zaugg, Holger J Schünemann and Martin Frey
    Citation: BMC Pulmonary Medicine 2004 4:5
  13. We tested the hypothesis that ventilatory drive in hypoxia and hypercapnia is inversely correlated with the number of hypopneas and obstructive apneas per hour of sleep (obstructive apnea hypopnea index, OAHI)...

    Authors: Ralph F Fregosi, Stuart F Quan, Andrew C Jackson, Kris L Kaemingk, Wayne J Morgan, Jamie L Goodwin, Jenny C Reeder, Rosaria K Cabrera and Elena Antonio
    Citation: BMC Pulmonary Medicine 2004 4:4
  14. Ventilator-associated pneumonia (VAP) which is an important part of all nosocomial infections in intensive care unit (ICU) is a serious illness with substantial morbidity and mortality, and increases costs of ...

    Authors: Riza Hakan Erbay, Ata Nevzat Yalcin, Mehmet Zencir, Simay Serin and Habip Atalay
    Citation: BMC Pulmonary Medicine 2004 4:3
  15. Interleukin-5 (IL-5) is thought to play a pivotal role in the pathogenesis of asthma. High levels of circulating IL-5 have been documented in acute asthma. However, serum IL-5 levels in mild to moderate asthma...

    Authors: Jose Joseph, Sheela Benedict, Wassef Safa and Maries Joseph
    Citation: BMC Pulmonary Medicine 2004 4:2
  16. Although the pathophysiological defect in primary ciliary dyskinesia (PCD; Siewert's / Kartagener's syndrome) is now well characterised, there are few studies of the impact of the condition upon health functio...

    Authors: I Christopher McManus, Hannah M Mitchison, Eddie MK Chung, Georgina F Stubbings and Naomi Martin
    Citation: BMC Pulmonary Medicine 2003 3:4
  17. Approximately ten percent of patients placed on mechanical ventilation during acute illness will require long-term ventilator support. Unfortunately, despite rehabilitation, some will never be liberated from t...

    Authors: Katherine P Hendra, Peter AL Bonis and Martin Joyce-Brady
    Citation: BMC Pulmonary Medicine 2003 3:3
  18. Fine needle aspiration is an important tool for diagnosis and preoperative evaluation of solitary nodules of the lung. It provides a definitive diagnosis in most patients at low cost with minimal trauma. Howev...

    Authors: Bahman Torkian, Rani Kanthan and Brent Burbridge
    Citation: BMC Pulmonary Medicine 2003 3:2
  19. HTLV-I infection has been linked to lung pathology and HTLV-II has been associated with an increased incidence of pneumonia and acute bronchitis. However it is unknown whether HTLV-I or -II infection alters pu...

    Authors: Edward L Murphy, Helen E Ownby, James W Smith, George Garratty, Sheila T Hutching, Ying Wu and Dannie I Ameti
    Citation: BMC Pulmonary Medicine 2003 3:1
  20. The heterogeneity of conditions underlying respiratory distress, whether classified clinically as acute lung injury (ALI) or the more severe acute respiratory distress syndrome (ARDS), has hampered efforts to ...

    Authors: Kang Fan and William A Nagle
    Citation: BMC Pulmonary Medicine 2002 2:5
  21. Tuberculosis is responsible for more female deaths around the earth than any other infectious disease. Reports have suggested that responses to tuberculosis may differ between men and women. We investigated ge...

    Authors: Peter Nsubuga, John L Johnson, Alphonse Okwera, Roy D Mugerwa, Jerrold J Ellner and Christopher C Whalen
    Citation: BMC Pulmonary Medicine 2002 2:4
  22. Lung function is a strong predictor of cardiovascular and all-cause mortality. Previous studies suggest that alcohol exposure may be linked to impaired pulmonary function through oxidant-antioxidant mechanisms...

    Authors: Holger J Schünemann, Brydon JB Grant, Jo L Freudenheim, Paola Muti, Susan E McCann, Deepa Kudalkar, Malathi Ram, Tom Nochajski, Marcia Russell and Maurizio Trevisan
    Citation: BMC Pulmonary Medicine 2002 2:3
  23. Attempts at gene therapy for the pulmonary manifestations of Cystic Fibrosis have relied mainly on airway delivery. However the efficiency of gene transfer and expression in the airway epithelia has not reache...

    Authors: Ameet Bakhai, Desmond J Sheridan and Charles C Coutelle
    Citation: BMC Pulmonary Medicine 2002 2:2
  24. To determine the accuracy of serum-effusion albumin gradient (SEAG) and pleural fluid to serum albumin ratio (ALBR) in the diagnostic separation of pleural effusion into transudate and exudate and to compare S...

    Authors: Jose Joseph, Padmanabhan Badrinath, Gurnam S Basran and Steven A Sahn
    Citation: BMC Pulmonary Medicine 2002 2:1
  25. It is known that tissue and serum sialic acid levels may be altered by malignant transformation. In this study, sialic acid levels were determined in bronchoalveolar lavage fluid (BAL) and serum in two groups ...

    Authors: Turgut Isitmangil, Gulbu Isitmangil, Yasemin Budak, Recep Aydilek and Mehmet Kutlu Celenk
    Citation: BMC Pulmonary Medicine 2001 1:4
  26. Takayasu's arteritis is a chronic systemic inflammatory disease that usually affects the aorta, its primary branches and occasionally the pulmonary and coronary arteries. Female gender in reproductive age and ...

    Authors: Beatrice Neidhart, Robert Kosek, Lucas M Bachmann and Claudia Stey
    Citation: BMC Pulmonary Medicine 2001 1:3
  27. Since the sterilising activity of new antituberculosis drugs is difficult to assess by conventional phase III studies, surrogate methods related to eventual relapse rates are required.

    Authors: Richard Brindle, Joseph Odhiambo and Denis Mitchison
    Citation: BMC Pulmonary Medicine 2001 1:2

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