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  1. Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) play important roles in the turnover of extracellular matrix and in the pathogenesis of idiopathic pulmonary fibrosis (IPF). This study ai...

    Authors: Jamie L. Todd, Richard Vinisko, Yi Liu, Megan L. Neely, Robert Overton, Kevin R. Flaherty, Imre Noth, L. Kristin Newby, Joseph A. Lasky, Mitchell A. Olman, Christian Hesslinger, Thomas B. Leonard, Scott M. Palmer and John A. Belperio
    Citation: BMC Pulmonary Medicine 2020 20:64
    Content type: Research article Published on:

  2. Asthma is one of the conditions that contributes to the global burden of respiratory diseases and has been previously associated with diet intake. The goal of this study was to determine the relationship betwe...

    Authors: Carla E. Tarazona-Meza, Corrine Hanson, Suzanne L. Pollard, Karina M. Romero Rivero, Rocio M. Galvez Davila, Sameera Talegawkar, Carlos Rojas, Jessica L. Rice, William Checkley and Nadia N. Hansel
    Citation: BMC Pulmonary Medicine 2020 20:63
    Content type: Research article Published on:

  3. Community-acquired pneumonia (CAP) requires urgent and specific antimicrobial therapy. However, the causal pathogen is typically unknown at the point when anti-infective therapeutics must be initiated. Physicia.....

    Authors: Claire Lhommet, Denis Garot, Leslie Grammatico-Guillon, Cassandra Jourdannaud, Pierre Asfar, Christophe Faisy, Grégoire Muller, Kimberly A. Barker, Emmanuelle Mercier, Sylvie Robert, Philippe Lanotte, Alain Goudeau, Helene Blasco and Antoine Guillon
    Citation: BMC Pulmonary Medicine 2020 20:62
    Content type: Research article Published on:

  4. This study aimed to explore the feasibility of applying the respiratory “critical care-sub-critical care-rehabilitation integrated management model” in severe stroke-associated pneumonia and evaluate its effect.

    Authors: Xue-Lin Wang, Li-Jun Ma, Xin-Gang Hu, Kai Wang and Jian-Jian Cheng
    Citation: BMC Pulmonary Medicine 2020 20:61
    Content type: Research article Published on:

  5. Factors associated with reduced daily physical activity (DPA) in patients with COPD are still controversial. Physical inactivity in COPD increases risk of cardiovascular disease, frequent exacerbations, reduce...

    Authors: Ali M. Albarrati, Nichola S. Gale, Maggie M. Munnery, John R. Cockcroft and Dennis J. Shale
    Citation: BMC Pulmonary Medicine 2020 20:60
    Content type: Research article Published on:

  7. Many individuals with cystic fibrosis (CF) die from respiratory failure without referral for lung transplant. Physician practices that may expedite, delay, or preclude referral, are poorly understood.

    Authors: Bethany L. Bartley, Carolyn E. Schwartz, Roland B. Stark, Anna M. Georgiopoulos, Deborah Friedman, Christopher J. Richards, Henry L. Dorkin, T. Bernard Kinane, Isabel P. Neuringer and Lael M. Yonker
    Citation: BMC Pulmonary Medicine 2020 20:58
    Content type: Research article Published on:

  8. Acute exacerbation (AE) of idiopathic pulmonary fibrosis (IPF) is devastating with no established treatment. This phenomenon involves disordered coagulation and excessive inflammatory reactions. As recombinant...

    Authors: Hiroyuki Kamiya and Ogee Mer Panlaqui
    Citation: BMC Pulmonary Medicine 2020 20:57
    Content type: Research article Published on:

  9. The 2012 Global Lung Function Initiative (GLI2012) provide multi-ethnic spirometric reference equations (SRE) for the 3–95 year-old age range, but Sub-Saharan African populations are not represented. This study a...

    Authors: Tafadzwa Madanhire, Rashida A. Ferrand, Engi F. Attia, Elopy N. Sibanda, Simba Rusakaniko and Andrea M. Rehman
    Citation: BMC Pulmonary Medicine 2020 20:56
    Content type: Research article Published on:

  10. There is low diagnostic accuracy of the proxy restrictive spirometric pattern (RSP) to identify true pulmonary restriction. This knowledge is based on patients referred for spirometry and total lung volume det...

    Authors: Kjell Torén, Linus Schiöler, Jonas Brisman, Andrei Malinovschi, Anna-Carin Olin, Göran Bergström and Björn Bake
    Citation: BMC Pulmonary Medicine 2020 20:55
    Content type: Research article Published on:

  11. Malignant central airway obstruction (MCAO) occurs in 20–30% of patients with primary pulmonary malignancy. Although bronchoscopic intervention is widely performed to treat MCAO, little data exist on the progn...

    Authors: Bo-Guen Kim, Beomsu Shin, Boksoon Chang, Hojoong Kim and Byeong-Ho Jeong
    Citation: BMC Pulmonary Medicine 2020 20:54
    Content type: Research article Published on:

  12. Following publication of the original article [1], the authors flagged that the article had gone to publishing with errors in Tables 1-3.

    Authors: P. Brownell, F. Piccolo, F. Brims, R. Norman and D. Manners
    Citation: BMC Pulmonary Medicine 2020 20:53
    Content type: Correction Published on:

    The original article was published in BMC Pulmonary Medicine 2020 20:24

  13. congenital pulmonary airway malformation (CPAM) is the most frequent congenital lung disorder. CPAM type 1 is the most common subtype, typically having a cystic radiological and histological appearance. Mucino...

    Authors: Timco Koopman, Bart L. Rottier, Arja ter Elst and Wim Timens
    Citation: BMC Pulmonary Medicine 2020 20:52
    Content type: Case report Published on:

  14. Patients with fibrotic interstitial lung disease (FILD) often experience gas exchange abnormalities and ventilatory limitations, resulting in reduced exercise capacity. High-flow nasal cannula (HFNC) oxygen th...

    Authors: Atsushi Suzuki, Masahiko Ando, Tomoki Kimura, Kensuke Kataoka, Toshiki Yokoyama, Eiichi Shiroshita and Yasuhiro Kondoh
    Citation: BMC Pulmonary Medicine 2020 20:51
    Content type: Research article Published on:

  17. Asthma is one of the chronic diseases which affects the airway, and inhalers are the preferred medications to treat this problem. Improper inhalational technique leads to decreased efficacy of the medication b...

    Authors: Tadesse Melaku Abegaz, Efrata Ashuro Shegena, Natnael Fentie Gessie, Eyob Alemayehu Gebreyohannes and Mohammed Assen Seid
    Citation: BMC Pulmonary Medicine 2020 20:48
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Pulmonary Medicine 2020 20:95

  18. Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is associated with infective triggers including bacterial or viral in many cases, and pneumonia is a major contributor to hospitalization f...

    Authors: Sunmin Park, Sang Jun Lee, Beomsu Shin, Seok Jeong Lee, Sang-Ha Kim, Woo Cheol Kwon, Jihye Kim and Myoung Kyu Lee
    Citation: BMC Pulmonary Medicine 2020 20:47
    Content type: Research article Published on:

  19. Lung transplantation (LTx) is still limited by the shortage of suitable donor lungs. Developing flexible surgical procedures can help to increase the chances of LTx by unfolding recipient-to-donor matching opt...

    Authors: Haruchika Yamamoto, Kentaroh Miyoshi, Shinji Otani, Takeshi Kurosaki, Seiichiro Sugimoto, Masaomi Yamane, Shinichi Toyooka, Motomu Kobayashi and Takahiro Oto
    Citation: BMC Pulmonary Medicine 2020 20:46
    Content type: Case report Published on:

  20. Bronchiectasis is a chronic infectious respiratory disease with diverse causes and ethnic or geographic differences. However, few large-scale studies of its etiology have been conducted in Asia. This study aim...

    Authors: Hung-Yu Huang, Fu-Tsai Chung, Chun-Yu Lo, Horng-Chyuan Lin, Yu-Tung Huang, Chih-Hsin Yeh, Chang-Wei Lin, Yu-Chen Huang and Chun-Hua Wang
    Citation: BMC Pulmonary Medicine 2020 20:45
    Content type: Database Published on:

  21. Lung cancer surgery is associated with a high incidence of postoperative pulmonary complications (PPCs). Preliminary evidence suggests that ERAS processes can reduce overall incidence of PPCs as short- and lon...

    Authors: Yu Zheng, Mao Mao, Meifang Ji, Qiugang Zheng, Liang Liu, Zhigang Zhao, Haiming Wang, Xiangyang Wei, Yulong Wang, Jiamin Chen, Huiqing Zhou, Qiaoqiao Liang, Ying Chen, Xintong Zhang, Lu Wang, Yihui Cheng…
    Citation: BMC Pulmonary Medicine 2020 20:44
    Content type: Study protocol Published on:

  22. Descending necrotizing mediastinitis is a severe infection of the mediastinum. This syndrome manifests as fever and chest pain following cough and sputum production. A 49-year-old woman presented with fever an...

    Authors: Rui-hai Ye, Jun-chao Yang, Hui-hua Hong, Yu-ping Mao, Yuan-hong Zhu, Yu Cao and Zhen Wang
    Citation: BMC Pulmonary Medicine 2020 20:43
    Content type: Case report Published on:

  23. Because of its analgesic and light sedative properties, the highly selective alpha-2 adrenergic receptor agonist dexmedetomidine (DEX) has been suggested for the treatment of septic patients, but its effect on...

    Authors: Peifen Chen, Jihong Jiang, Yunhe Zhang, Guobao Li, Zhihui Qiu, Mitchell M. Levy and Baoji Hu
    Citation: BMC Pulmonary Medicine 2020 20:42
    Content type: Research article Published on:

  24. Targeted lung denervation (TLD) is a bronchoscopically delivered ablation therapy that selectively interrupts pulmonary parasympathetic nerve signaling. The procedure has the potential to alter airway smooth m...

    Authors: Dirk-Jan Slebos, Bruno Degano, Arschang Valipour, Pallav L. Shah, Gaetan Deslée and Frank C. Sciurba
    Citation: BMC Pulmonary Medicine 2020 20:41
    Content type: Study protocol Published on:

  26. Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approa...

    Authors: Raquel Nazareth, Maria-Jesus Chasqueira, Maria-Lúcia Rodrigues, Carolina Paulino, Catarina Conceição, Lia Lêdo, Úrsula Segura, Madalena Santos, António Messias, Pedro Póvoa and Paulo Paixão
    Citation: BMC Pulmonary Medicine 2020 20:39
    Content type: Research article Published on:

  27. Massive hemoptysis is a serious complication in Cystic Fibrosis (CF), occurring commonly in older patients. Bronchial artery embolization (BAE) can be performed to stop the bleeding. BAE is generally safe and ...

    Authors: V. Terlizzi, M. Botti, G. Gabbani, F. Fanelli, M. De Martino and G. Taccetti
    Citation: BMC Pulmonary Medicine 2020 20:38
    Content type: Case report Published on:

  28. Prolonged and difficult weaning is associated with higher rates of complications and mortality. Therefore, it is important to identify the associated factors.

    Authors: Renyu Ding, Yulan Meng, Xingjuan Jia and Xiaochun Ma
    Citation: BMC Pulmonary Medicine 2020 20:37
    Content type: Case report Published on:

  29. Lung cancer is the most common cause of cancer related death worldwide and survival is poor. Patients with lung cancer may develop a critical illness, but it is unclear what features are associated with an Int...

    Authors: Kathryn Puxty, Christopher H. Grant, Philip McLoone, Billy Sloan, Tara Quasim, Kate Hulse and David S. Morrison
    Citation: BMC Pulmonary Medicine 2020 20:36
    Content type: Research article Published on:

  30. Hump-nosed viper bite, the commonest venomous snake bite in Sri Lanka, is associated with significant morbidity. Specific anti-venom is not available for hump-nosed viper envenomation which is usually managed ...

    Authors: Arthihai Srirangan, Jagath Pushpakumara and Kamani Wanigasuriya
    Citation: BMC Pulmonary Medicine 2020 20:35
    Content type: Case report Published on:

  31. Pulmonary alveolar proteinosis (PAP) is a very rare lung disease and its prevalence and incidence remain unclear. The prevalence and incidence of PAP were investigated by using nationwide claims data from the ...

    Authors: Hee-young Yoon, Ji Hyeon Kim, Ye-Jee Kim and Jin Woo Song
    Citation: BMC Pulmonary Medicine 2020 20:34
    Content type: Research article Published on:

  32. Early detection of pulmonary contamination in children with cystic fibrosis (CF) is essential since these children are vulnerable to Pseudomonas aeruginosa (P. aeruginosa) colonization. In Iran, home nebulization...

    Authors: Seyed Ahmad Tabatabaii, Ghamartaj Khanbabaee, Saeed Sadr, Nazanin Farahbakhsh, Maryam Kazemi Aghdam, Saran Lotfollahzadeh, Amirhossein Hosseini, Naghi Dara, Mohammad Nanbakhsh and Fatemeh Abdollah Gorji
    Citation: BMC Pulmonary Medicine 2020 20:33
    Content type: Research article Published on:

  33. Chronic hypersensitivity pneumonitis (cHP) is a disease caused by exposure to inhaled environmental antigens. Diagnosis of cHP is influenced by the awareness of the disease prevalence, which varies significant...

    Authors: Jessie P. Gu, Chen-Liang Tsai, Nicholas G. Wysham and Yuh-Chin T. Huang
    Citation: BMC Pulmonary Medicine 2020 20:32
    Content type: Research article Published on:

  34. Obstructive sleep apnea syndrome (OSAS) is a common disorder that is accompanied by structural brain changes. This meta-analysis aimed to evaluate the effect of OSAS on the serum levels of astrocytic protein (...

    Authors: Farzad Rezaei, Hooshyar Abbasi, Masoud Sadeghi and Mohammad Moslem Imani
    Citation: BMC Pulmonary Medicine 2020 20:31
    Content type: Research article Published on:

  35. Cystic airspace is an uncommon imaging manifestation involved in non-small lung cancer (NSCLC). Diffuse cystic lesion is even rarer as pulmonary manifestation of NSCLC. In the present study, we reported a rare...

    Authors: Xianhua Gui, Jingjing Ding, Yan Li, Min Yu, Tingting Chen, Mei Huang and Yonglong Xiao
    Citation: BMC Pulmonary Medicine 2020 20:30
    Content type: Case report Published on:

  36. Chronic obstructive pulmonary disease (COPD) is combination of progressive lung diseases. The diagnosis of COPD is generally based on the pulmonary function testing, however, difficulties underlie in prognosis...

    Authors: Kazushi Matsumura and Shigeaki Ito
    Citation: BMC Pulmonary Medicine 2020 20:29
    Content type: Technical advance Published on:

  37. The risk of injury directly related to hospitalization for motor vehicle accidents (MVAs) in the obstructive sleep apnea (OSA) patients has not been thoroughly understood. Our study aimed to examine the associ...

    Authors: Yi-Chang Lin, Tien-Yu Chen, Wu-Chien Chien, Chi-Hsiang Chung, Hsin-An Chang, Yu-Chen Kao, Chien-Sung Tsai, Chih-Sheng Lin and Nian-Shen Tzeng
    Citation: BMC Pulmonary Medicine 2020 20:28
    Content type: Research article Published on:

  38. Idiopathic pulmonary fibrosis (IPF) is a progressive and fibrosing lung disease with poor prognosis. Pirfenidone and nintedanib are anti-fibrotic drugs used for patients with IPF. These drugs reduce the rate o...

    Authors: Takumi Yoshikawa, Mitsuo Otsuka, Hirofumi Chiba, Kimiyuki Ikeda, Yuki Mori, Yasuaki Umeda, Hirotaka Nishikiori, Koji Kuronuma and Hiroki Takahashi
    Citation: BMC Pulmonary Medicine 2020 20:27
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Pulmonary Medicine 2020 20:131

  39. IL-17A directly induces epithelial-mesenchymal transition (EMT) in alveolar epithelial cells. It could coordinate with cigarette smoke extract (CSE) to promote proliferation of bronchial epithelial cells. In t...

    Authors: Libing Ma, Ming Jiang, Xiaoli Zhao, Jingyi Sun, Qilu Pan and Shuyuan Chu
    Citation: BMC Pulmonary Medicine 2020 20:26
    Content type: Research article Published on:

  40. Interstitial lung disease (ILD) is the most common and important pulmonary manifestation of rheumatoid arthritis (RA). A radiological honeycomb pattern has been described in diverse forms of ILD that can impac...

    Authors: Hideaki Yamakawa, Shintaro Sato, Tomotaka Nishizawa, Rie Kawabe, Tomohiro Oba, Akari Kato, Masanobu Horikoshi, Keiichi Akasaka, Masako Amano, Hiroki Sasaki, Kazuyoshi Kuwano and Hidekazu Matsushima
    Citation: BMC Pulmonary Medicine 2020 20:25
    Content type: Research article Published on:

  41. Lung cancer is the leading cause of cancer mortality in Australia. Guidelines suggest that patients with suspected lung cancer on thoracic imaging be referred for urgent specialist review. However, the term “s...

    Authors: P. Brownell, F. Piccolo, F. Brims, R. Norman and D. Manners
    Citation: BMC Pulmonary Medicine 2020 20:24
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Pulmonary Medicine 2020 20:53

  42. Recent research has proposed an association between desaturation during a six minute walking test (6MWT) and osteoporosis in an elderly group of individuals with non-cystic fibrosis bronchiectasis. A causative...

    Authors: Owen W. Tomlinson and Dimitris Vlachopoulos
    Citation: BMC Pulmonary Medicine 2020 20:23
    Content type: Correspondence Published on:

  43. We investigated the association between a combination of two markers, peripheral (PEC) and bronchoalveolar lavage (BAL) eosinophil percentage (BEP), and oxygen requirements in patients with acute eosinophilic ...

    Authors: Joon Young Choi, Jeong Uk Lim, Ho Jung Jeong, Ji Eun Lee and Chin Kook Rhee
    Citation: BMC Pulmonary Medicine 2020 20:22
    Content type: Research article Published on:

  44. Lung fibrosis is a serious life-threatening condition whose manifestation varies according to the localization and characteristics of fibroblasts, which are considered heterogeneous. Therefore, to better under...

    Authors: Sayomi Matsushima, Yoichiro Aoshima, Taisuke Akamatsu, Yasunori Enomoto, Shiori Meguro, Isao Kosugi, Hideya Kawasaki, Tomoyuki Fujisawa, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, Kazuhito Funai, Takafumi Suda and Toshihide Iwashita
    Citation: BMC Pulmonary Medicine 2020 20:21
    Content type: Research article Published on:

  45. Both mitophagy, a selective mechanism for clearance of mitochondria, and mitochondrial biogenesis are key processes determining mitochondrial content and oxidative capacity of the musculature. Abnormalities in...

    Authors: Pieter A. Leermakers, Alexander H. V. Remels, Ramon C. J. Langen, Annemie M. W. J. Schols and Harry R. Gosker
    Citation: BMC Pulmonary Medicine 2020 20:20
    Content type: Research article Published on:

  46. Previous studies demonstrated an important role for connexin 43 (Cx43) in the regulation of apoptosis by influencing mitochondrial functions. This study aimed to investigate the relationship between Cx43 and l...

    Authors: Jia-wei Ma, Dan-dan Ji, Qian-qian Li, Ting Zhang and Liang Luo
    Citation: BMC Pulmonary Medicine 2020 20:19
    Content type: Research article Published on:

  47. Community-acquired pneumonia (CAP) is one of the leading causes of morbidity and mortality worldwide, often leading to hospital admissions. In Portugal, the factors associated with in-hospital mortality due to...

    Authors: Ezequiel Pessoa, Cristina Bárbara, Laura Viegas, Andreia Costa, Matilde Rosa and Paulo Nogueira
    Citation: BMC Pulmonary Medicine 2020 20:18
    Content type: Research article Published on:

  48. Following publication of the original article [1], the authors flagged that the article had published with an error in ‘Table 1’.

    Authors: Anke Kindermann, Leonore Binder, Jan Baier, Beate Gündel, Andreas Simm, Roland Haase and Babett Bartling
    Citation: BMC Pulmonary Medicine 2020 20:17
    Content type: Correction Published on:

    The original article was published in BMC Pulmonary Medicine 2019 19:245

  49. The 2013 update of the Infection Prevention and Control (IP&C) Guideline outlined recommendations to prevent the spread of CF respiratory pathogens. We aimed to investigate the current infection control practi...

    Authors: Rebecca Elizabeth Stockwell, Michelle ELizabeth Wood, Emma Ballard, Vanessa Moore, Claire Elizabeth Wainwright and Scott Cameron Bell
    Citation: BMC Pulmonary Medicine 2020 20:16
    Content type: Research article Published on:

  50. The understanding of the epidemiology of bronchiectasis is still affected by major limitations with very few data published worldwide. The aim of this study was to estimate the epidemiological burden of bronch...

    Authors: Stefano Aliberti, Giovanni Sotgiu, Francesco Lapi, Andrea Gramegna, Claudio Cricelli and Francesco Blasi
    Citation: BMC Pulmonary Medicine 2020 20:15
    Content type: Research article Published on:
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BMC Pulmonary Medicine

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