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  1. According to international guidelines, the goal of asthma management is to achieve and maintain control of the disease, which can be assessed using composite measures. Prospective studies are required to deter...

    Authors: Fulvio Braido, Guy Brusselle, Eleonora Ingrassia, Gabriele Nicolini, David Price, Nicolas Roche, Joan B Soriano and Heinrich Worth
    Citation: BMC Pulmonary Medicine 2013 13:18
  2. Favorable effects of formal pulmonary rehabilitation in selected moderate to severe COPD patients are well established. Few data are available on the effects and costs of integrated disease management (IDM) pr...

    Authors: Annemarije L Kruis, Melinde RS Boland, Catharina H Schoonvelde, Willem JJ Assendelft, Maureen PMH Rutten-van Mölken, Jacobijn Gussekloo, Apostolos Tsiachristas and Niels H Chavannes
    Citation: BMC Pulmonary Medicine 2013 13:17
  3. Penicillium species are among the most common fungi present in the environment and are usually considered non-pathogenic to humans. However, in immunocompromised hosts they can be virulent pathogens and can caus...

    Authors: Chiyako Oshikata, Naomi Tsurikisawa, Akemi Saito, Maiko Watanabe, Yoichi Kamata, Maki Tanaka, Takahiro Tsuburai, Hiroyuki Mitomi, Kosuke Takatori, Hiroshi Yasueda and Kazuo Akiyama
    Citation: BMC Pulmonary Medicine 2013 13:16
  4. Current asthma management guidelines are based on the level of asthma control. The impact of asthma control on health care resources and quality of life (QoL) is insufficiently studied. EUCOAST study was desig...

    Authors: Marianne Doz, Christos Chouaid, Laure Com-Ruelle, Eduardo Calvo, Max Brosa, Julien Robert, Laurent Decuypère, Celine Pribil, Alicia Huerta and Bruno Detournay
    Citation: BMC Pulmonary Medicine 2013 13:15
  5. F-fluorodeoxyglucose positron emission tomography (FDG-PET) is increasingly used to investigate for malignancy in the evaluation of pulmonary nodules, yet both active tuberculosis (TB) and malignancy have high...

    Authors: Scott K Heysell, Tania A Thomas, Costi D Sifri, Patrice K Rehm and Eric R Houpt
    Citation: BMC Pulmonary Medicine 2013 13:14
  6. Reduced plasma nitrate (NOx) levels and increased urinary norepinephrine (U-NE) levels have been described in severe obstructive sleep apnea (OSA), and are reverted by continuous positive airway pressure (CPAP). ...

    Authors: Paula Pinto, Cristina Bárbara, Joseph M Montserrat, Rita S Patarrão, Maria P Guarino, Miguel M Carmo, Maria P Macedo, Cristina Martinho, Rita Dias and Maria JM Gomes
    Citation: BMC Pulmonary Medicine 2013 13:13
  7. Non-invasive mechanical ventilation (NIV) in patients with acute respiratory failure has been traditionally determined based on clinical assessment and changes in blood gases, with NIV support pressures manual...

    Authors: Killen Harold Briones Claudett, Monica Briones Claudett, Miguel Chung Sang Wong, Alberto Nuques Martinez, Ricardo Soto Espinoza, Mayra Montalvo, Antonio Esquinas Rodriguez, Gumersindo Gonzalez Diaz and Michelle Grunauer Andrade
    Citation: BMC Pulmonary Medicine 2013 13:12
  8. The editors of BMC Pulmonary Medicine would like to thank all our reviewers who have contributed to the journal in Volume 12 (2012).

    Authors: Tim Shipley
    Citation: BMC Pulmonary Medicine 2013 13:7
  9. Phenotyping asthma according to airway inflammation allows identification of responders to targeted therapy. Induced sputum is technically demanding. We aimed to identify predictors of sputum inflammatory phen...

    Authors: Florence N Schleich, Maité Manise, Jocelyne Sele, Monique Henket, Laurence Seidel and Renaud Louis
    Citation: BMC Pulmonary Medicine 2013 13:11
  10. Obstructive sleep apnea (OSA) is a common disease, affecting approximately 2% of women and 4% of men residing in Western communities. No systematically reviewed data are available about the prevalence of this ...

    Authors: Aibek E Mirrakhimov, Talant Sooronbaev and Erkin M Mirrakhimov
    Citation: BMC Pulmonary Medicine 2013 13:10
  11. The increased use of computed tomography pulmonary angiography (CTPA) is often justified by finding alternative diagnoses explaining patients’ symptoms. However, this has not been rigorously examined.

    Authors: Subani Chandra, Pralay K Sarkar, Divay Chandra, Nicole E Ginsberg and Rubin I Cohen
    Citation: BMC Pulmonary Medicine 2013 13:9
  12. Interstitial lung disease encompasses a diverse group of chronic lung conditions characterised by distressing dyspnoea, fatigue, reduced exercise tolerance and poor health-related quality of life. Exercise tra...

    Authors: Leona Dowman, Christine F McDonald, Catherine Hill, Annemarie Lee, Kathryn Barker, Claire Boote, Ian Glaspole, Nicole Goh, Annemarie Southcott, Angela Burge, Rebecca Ndongo, Alicia Martin and Anne E Holland
    Citation: BMC Pulmonary Medicine 2013 13:8
  13. The aim of our study was to validate a Greek translation of the Berlin Questionnaire (BQ) for obstructive sleep apnoea syndrome (OSAS) and to explore whether this screening questionnaire could be used to help ...

    Authors: Izolde Bouloukaki, Ioannis D Komninos, Charalampos Mermigkis, Katerina Micheli, Maria Komninou, Violeta Moniaki, Eleni Mauroudi, Nikolaos M Siafakas and Sophia E Schiza
    Citation: BMC Pulmonary Medicine 2013 13:6
  14. Acute exacerbations of chronic bronchitis (AECB), including chronic obstructive pulmonary disease (AECOPD), represent a substantial patient burden. Few data exist on outpatient antibiotic management for AECB/A...

    Authors: Alexander Chuchalin, Maryna Zakharova, Dejan Dokic, Mahir Tokić, Hans-Peter Marschall and Thomas Petri
    Citation: BMC Pulmonary Medicine 2013 13:5
  15. Focal ground-glass opacity (GGO) on thin-section computed tomography (CT) may be seen in atypical adenomatous hyperplasia (AAH), adenocarcinoma in situ that has recently been renamed from bronchioloalveolar ca...

    Authors: Noriko Sudo, Atsushi Nambu, Takana Yamakawa, Masashi Kawamoto, Shozo Fujino, Masato Watanabe, Kunio Mizuguchi and Masao Tago
    Citation: BMC Pulmonary Medicine 2013 13:3
  16. No studies have investigated the immediate impact of receiving an allogeneic hematopoietic stem cell transplant (HSCT) on pulmonary inflammation or lung function.

    Authors: Alexandra Enocson, Richard Hubbard, Tricia McKeever, Nigel Russell, Jennifer Byrne, Emma Das-Gupta, Lynne Watson and Andrew W Fogarty
    Citation: BMC Pulmonary Medicine 2013 13:2
  17. Functional exercise capacity in people with asbestos related pleural disease (ARPD) is unknown and there are no data on health-related quality of life (HRQoL). The primary aims were to determine whether functi...

    Authors: Marita T Dale, Zoe J McKeough, Phillip A Munoz, Peter Corte, Peter TP Bye and Jennifer A Alison
    Citation: BMC Pulmonary Medicine 2013 13:1
  18. Symptom-based questionnaires can be a cost effective tool enabling identification and diagnosis of patients with respiratory illnesses in resource limited setting. This study aimed to determine the correlation...

    Authors: Imran Naeem Abbasi, Adeel Ahsan and Asaad Ahmed Nafees
    Citation: BMC Pulmonary Medicine 2012 12:81
  19. Acute asthma attacks remain a frequent cause of emergency department (ED) visits and hospital admission. Many factors encourage patients to seek asthma treatment at the emergency department. These factors may ...

    Authors: Hamdan AL-Jahdali, Ahmed Anwar, Abdullah AL-Harbi, Salim Baharoon, Rabih Halwani, Abdulllah Al Shimemeri and Saleh Al-Muhsen
    Citation: BMC Pulmonary Medicine 2012 12:80
  20. During the past decades, numerous efforts have been made to decrease the death rate among lung cancer patients. Nonetheless, the improvement in long-term survival has been limited and lung cancer is still a de...

    Authors: Marlies E Heuvers, Joost P Hegmans, Bruno H Stricker and Joachim G Aerts
    Citation: BMC Pulmonary Medicine 2012 12:77
  21. Oil tanks containing a mixture of hydrocarbons, including sulphuric compounds, exploded and caught fire in an industrial harbour. This study assesses airway symptoms and lung function in the nearby population ...

    Authors: Jens-Tore Granslo, Magne Bråtveit, Bjørg Eli Hollund, Ågot Irgens, Cecilie Svanes, Nils Magerøy and Bente Elisabeth Moen
    Citation: BMC Pulmonary Medicine 2012 12:76
  22. Little is known concerning the degree to which initiation of sildenafil for pulmonary arterial hypertension (PAH) impacts patterns of healthcare utilization and costs.

    Authors: Ariel Berger, John Edelsberg, Simon Teal, Marko A Mychaskiw and Gerry Oster
    Citation: BMC Pulmonary Medicine 2012 12:75
  23. Glycopyrronium bromide (NVA237) is an inhaled long-acting muscarinic antagonist in development for treatment of COPD. This study compared the efficacy and safety of once-daily (OD) and twice-daily (BID) glycop...

    Authors: Helen Arievich, Tim Overend, Didier Renard, Michael Gibbs, Vijay Alagappan, Michael Looby and Donald Banerji
    Citation: BMC Pulmonary Medicine 2012 12:74
  24. Objective measurement of airflow obstruction by spirometry is an essential part of the diagnosis of asthma or COPD. During exacerbations, the feasibility and utility of spirometry to confirm the diagnosis of a...

    Authors: Valentin Prieto Centurion, Frank Huang, Edward T Naureckas, Carlos A Camargo Jr, Jeffrey Charbeneau, Min J Joo, Valerie G Press and Jerry A Krishnan
    Citation: BMC Pulmonary Medicine 2012 12:73
  25. Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a recently reported group of disorders characterized by fibrotic thickening of the pleural and subpleural parenchyma predominantly in the upper lobes. We ...

    Authors: Hideki Kusagaya, Yutaro Nakamura, Masato Kono, Yusuke Kaida, Shigeki Kuroishi, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Koshimizu, Koshi Yokomura, Naoki Inui, Takafumi Suda, Thomas V Colby and Kingo Chida
    Citation: BMC Pulmonary Medicine 2012 12:72
  26. Chronic obstructive pulmonary disease (COPD) is a respiratory condition characterised by dyspnoea, excessive sputum production, chronic cough, bronchitis and emphysema. Functionally, exercise tolerance is poor...

    Authors: Trentham Furness, Nicole Bate, Liam Welsh, Geraldine Naughton and Christian Lorenzen
    Citation: BMC Pulmonary Medicine 2012 12:71
  27. Although Group A beta hemolytic streptococcus (GABHS) can cause bacterial pharyngitis, the most common etiology is viral; despite this viral etiology, antibiotics are commonly prescribed for this infection in ind...

    Authors: Amber Hanif Palla, Rafeeq Alam Khan, Anwar H Gilani and Fawziah Marra
    Citation: BMC Pulmonary Medicine 2012 12:70
  28. There is some evidence that singing lessons may be of benefit to patients with chronic obstructive pulmonary disease (COPD). It is not clear how much of this benefit is specific to singing and how much relates...

    Authors: Victoria M Lord, Victoria J Hume, Julia L Kelly, Phoene Cave, Judith Silver, Maya Waldman, Chris White, Cayley Smith, Rebecca Tanner, Melissa Sanchez, William D-C Man, Michael I Polkey and Nicholas S Hopkinson
    Citation: BMC Pulmonary Medicine 2012 12:69

    The Erratum to this article has been published in BMC Pulmonary Medicine 2014 14:181

  29. The measurement of fractional concentration of nitric oxide in exhaled air (FeNO) is valuable for the assessment of airway inflammation. Offline measurement of FeNO has been used in some epidemiologic studies....

    Authors: Yoshiko Yoda, Naruhito Otani, Hideki Hasunuma, Hiroshi Kanegae and Masayuki Shima
    Citation: BMC Pulmonary Medicine 2012 12:68
  30. This study investigated the efficacy and safety of a new asthma therapy combining fluticasone propionate and formoterol fumarate (fluticasone/formoterol; flutiform ®), administered twice daily (b.i.d.) via a sing...

    Authors: Robert A Nathan, Anthony D’Urzo, Viktor Blazhko and Kirsten Kaiser
    Citation: BMC Pulmonary Medicine 2012 12:67
  31. Mechanical ventilation (MV) is imperative in many forms of acute respiratory failure (ARF) in COPD patients. Previous studies have shown the difficulty to identify parameters predicting the outcome of COPD pat...

    Authors: Ketty Langlet, Thierry Van Der Linden, Claire Launois, Caroline Fourdin, Philippe Cabaret, Nadia Kerkeni, Coralie Barbe, François Lebargy and Gaetan Deslée
    Citation: BMC Pulmonary Medicine 2012 12:66
  32. In well-child care it is difficult to determine whether preschool children with asthma symptoms actually have or will develop asthma at school age. The PIAMA (Prevention and Incidence of Asthma and Mite Allerg...

    Authors: Esther Hafkamp-de Groen, Hester F Lingsma, Daan Caudri, Alet Wijga, Vincent WV Jaddoe, Ewout W Steyerberg, Johan C de Jongste and Hein Raat
    Citation: BMC Pulmonary Medicine 2012 12:65
  33. Tobacco smoking remains the leading cause of preventable death in America, claiming 450,000 lives annually. Chronic Obstructive Pulmonary Disease, caused by smoking in the vast majority of cases, became the th...

    Authors: Stephen A Martin, Bartolome R Celli, Joseph R DiFranza, Stephen J Krinzman, Jennifer G Clarke, Herbert Beam, Sandra Howard, Melissa Foster and Robert J Goldberg
    Citation: BMC Pulmonary Medicine 2012 12:64
  34. The recommendations for the treatment of moderate persistent asthma in the Global Initiative for Asthma (GINA) guidelines for paediatric asthma are mainly based on scientific evidence extrapolated from studies...

    Authors: Lonneke B van der Mark, PH Edo Lyklema, Ronald B Geskus, Jacob Mohrs, Patrick JE Bindels, Wim MC van Aalderen and Gerben ter Riet
    Citation: BMC Pulmonary Medicine 2012 12:63
  35. Inhalation of helium-oxygen (He/O2) mixtures has been explored as a means to lower the work of breathing of patients with obstructive lung disease. Non-invasive ventilation (NIV) with positive pressure support is...

    Authors: Andrew R Martin, Ira M Katz, Katharina Jenöfi, Georges Caillibotte, Laurent Brochard and Joëlle Texereau
    Citation: BMC Pulmonary Medicine 2012 12:62
  36. Dyspnea is very frequent in obese subjects. However, its assessment is complex in clinical practice. The modified Medical Research Council scale (mMRC scale) is largely used in the assessment of dyspnea in chr...

    Authors: Claire Launois, Coralie Barbe, Eric Bertin, Julie Nardi, Jeanne-Marie Perotin, Sandra Dury, François Lebargy and Gaëtan Deslee
    Citation: BMC Pulmonary Medicine 2012 12:61
  37. Obstructive sleep apnea (OSA) is becoming increasingly prevalent in North America and has been described in association with specific chronic diseases, particularly cardiovascular diseases. In primary care, wh...

    Authors: Laurence Robichaud-Hallé, Michel Beaudry and Martin Fortin
    Citation: BMC Pulmonary Medicine 2012 12:60
  38. Mechanical ventilation (MV) is the primary form of support for acute respiratory distress syndrome (ARDS) patients. However, intra- and inter- patient-variability reduce the efficacy of general protocols. Mode...

    Authors: Yeong Shiong Chiew, J Geoffrey Chase, Bernard Lambermont, Nathalie Janssen, Christoph Schranz, Knut Moeller, Geoffrey M Shaw and Thomas Desaive
    Citation: BMC Pulmonary Medicine 2012 12:59
  39. Breathlessness is a common and distressing symptom affecting many patients with advanced disease both from malignant and non-malignant origin. A combination of pharmacological and non-pharmacological measures ...

    Authors: Claudia Bausewein, Caroline Jolley, Charles Reilly, Paula Lobo, Jane Kelly, Helene Bellas, Preety Madan, Caty Panell, Elmien Brink, Chiara De Biase, Wei Gao, Caroline Murphy, Paul McCrone, John Moxham and Irene J Higginson
    Citation: BMC Pulmonary Medicine 2012 12:58
  40. 18F-FDG PET/CT (PET) is useful in assessing inflammatory activity in sarcoidosis. However, no appropriate indications are available. The aim of this study was to develop a prediction rule that can be used to ide...

    Authors: Rémy LM Mostard, Sander MJ Van Kuijk, Johny A Verschakelen, Marinus JPG van Kroonenburgh, Patty J Nelemans, Petal AHM Wijnen and Marjolein Drent
    Citation: BMC Pulmonary Medicine 2012 12:57
  41. The association between endotoxin exposure and asthma is complex and has been associated with rural living. We examined the relationship between domestic endotoxin and asthma or wheeze among rural school-aged ...

    Authors: Joshua A Lawson, James A Dosman, Donna C Rennie, Jeremy R Beach, Stephen C Newman, Trever Crowe and Ambikaipakan Senthilselvan
    Citation: BMC Pulmonary Medicine 2012 12:56
  42. Napsin A, an aspartic protease, is mainly expressed in alveolar type-II cells and renal proximal tubules and is a putative immunohistochemical marker for pulmonary adenocarcinomas. This study sought to determi...

    Authors: Takuya Samukawa, Tsutomu Hamada, Hirofumi Uto, Masakazu Yanagi, Go Tsukuya, Tsuyoshi Nosaki, Masahiro Maeda, Takashi Hirano, Hirohito Tsubouchi and Hiromasa Inoue
    Citation: BMC Pulmonary Medicine 2012 12:55
  43. The 6-minute walk test evaluates the effect of pharmacologic intervention in adults with pulmonary arterial hypertension (PAH) but, for reasons of compliance or reliability, may not be appropriate for children...

    Authors: Joseph C Cappelleri, Lie-Ju Hwang, Jack Mardekian and Marko A Mychaskiw
    Citation: BMC Pulmonary Medicine 2012 12:54
  44. Patients with chronic obstructive pulmonary disease (COPD) often experience depression and anxiety, but little information is available regarding Chinese patients with these conditions. The present study asses...

    Authors: Peian Lou, Yanan Zhu, Peipei Chen, Pan Zhang, Jiaxi Yu, Ning Zhang, Na Chen, Lei Zhang, Hongmin Wu and Jing Zhao
    Citation: BMC Pulmonary Medicine 2012 12:53
  45. Regular review and support for asthma self-management is promoted in guidelines. A randomised controlled trial suggested that unscheduled health care usage was similar when patients were offered self managemen...

    Authors: Nicola J Roberts, Kathleen A Boyd, Andrew H Briggs, Ann L Caress and Martyn R Partridge
    Citation: BMC Pulmonary Medicine 2012 12:52
  46. Respiratory tract infections (RTIs) may be more severe in those with asthma or COPD and these patients are more frequently in need of health care. The aim of the study was to describe the frequency of RTI symp...

    Authors: Hasse Melbye, Lisa Joensen, Mette Bech Risør and Peder A Halvorsen
    Citation: BMC Pulmonary Medicine 2012 12:51
  47. Bronchodilator response in patients with asthma is evaluated based on post-bronchodilator increase in forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). However, the need for additiona...

    Authors: Karen S Azevedo, Ronir R Luiz, Patricia RM Rocco and Marcus B Conde
    Citation: BMC Pulmonary Medicine 2012 12:49

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