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  1. Adult patients with cystic fibrosis (CF) experience daily physical symptoms and disabilities that can be challenging to address for health care teams.

    Authors: Sandra Dury, Jeanne-Marie Perotin, Bruno Ravoninjatovo, Catherine Llerena, Julien Ancel, Pauline Mulette, Muriel Griffon, Sophie Carré, Amélie Perrin, François Lebargy, Gaëtan Deslée and Claire Launois

    Citation: BMC Pulmonary Medicine 2021 21:270

    Content type: Research

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  2. Bronchiectasis is a major contributor to respiratory morbidity and healthcare utilization in children. Children with bronchiectasis exhibit low levels of physical activity (PA) and poor fundamental movement sk...

    Authors: Barbara Joschtel, Sjaan R. Gomersall, Sean Tweedy, Helen Petsky, Anne B. Chang and Stewart G. Trost

    Citation: BMC Pulmonary Medicine 2021 21:269

    Content type: Research

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  3. Curcumin, a derivative of the spice turmeric, has been adopted by Eastern medicine for centuries as an adjunct to treat several medical conditions (e.g., anorexia and arthritis) because of its well-established...

    Authors: Michele Quan, Abdullah Alismail, Noha Daher, Derrick Cleland, Sonia Chavan and Laren D. Tan

    Citation: BMC Pulmonary Medicine 2021 21:268

    Content type: Study protocol

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  4. The aim of the study is to estimate the prevalence of atelectasis assessed with computer tomography (CT) in SARS-CoV-2 pneumonia and the relationship between the amount of atelectasis with oxygenation impairme...

    Authors: Álvaro Mingote, Andrea Albajar, Paulino García Benedito, Jessica Garcia-Suarez, Paolo Pelosi, Lorenzo Ball and Javier García-Fernández

    Citation: BMC Pulmonary Medicine 2021 21:267

    Content type: Research

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  5. Incorrect use of inhalers among asthma and COPD patients is very prevalent. Yet, no single intervention is considered standard of care. We aimed to conduct a COPD-specific investigation of active one-on-one co...

    Authors: Jin Sun Kim, Nader Hashweh, Hannah Li, Salik Choudhary, Sadashiv Santosh and Edward Charbek

    Citation: BMC Pulmonary Medicine 2021 21:266

    Content type: Research article

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  6. The objective of the present study is to describe the clinical, diagnostic, radiological and therapeutic aspects of osteoarticular tuberculosis (OATB) in patients in a tertiary pediatric hospital, to know if t...

    Authors: Napoleón González Saldaña, Mercedes Macías Parra, Luis Xochihua Díaz, Martin Palavicini Rueda, Ana Jocelyn Carmona Vargas, José Iván Castillo Bejarano, Quetzalli Veloz Corona, Hugo Juárez Olguín and Juan Luis Chavez Pacheco

    Citation: BMC Pulmonary Medicine 2021 21:265

    Content type: Research

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  7. Acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by acute hypoxaemia, and few studies have reported the incidence of deep vein thrombosis (DVT) in direct ARDS caused by bacterial...

    Authors: Na Cui, Song Mi, Chunguo Jiang, Wanlu Sun, Wenping Mao, Liming Zhang and Xiaokai Feng

    Citation: BMC Pulmonary Medicine 2021 21:264

    Content type: Research

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  8. Kartagener syndrome is a subtype of primary ciliary dyskinesia that may exhibit various symptoms including neonatal respiratory distress and frequent infections of the lung, sinus and middle ear because of the...

    Authors: Lina Wang, Xin Zhao, Hang Liang, Li Zhang, Chunyan Li, Deli Li, Xiangfeng Meng, Fanzheng Meng and Mao Gao

    Citation: BMC Pulmonary Medicine 2021 21:263

    Content type: Case report

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  9. While lung transplant (LTX) can be an effective therapy to provide the survival benefit in selected populations, post-transplant outcome in LTX recipients with bronchiectasis other than cystic fibrosis (CF) ha...

    Authors: Takashi Hirama, Fumiko Tomiyama, Hirotsugu Notsuda, Tatsuaki Watanabe, Yui Watanabe, Hisashi Oishi and Yoshinori Okada

    Citation: BMC Pulmonary Medicine 2021 21:261

    Content type: Research

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  10. The 6th World Symposium on Pulmonary Hypertension (Nice 2018) proposed a new definition of pre-capillary pulmonary hypertension (PH) as a condition with mean pulmonary artery pressure (mPAP) > 20 mmHg, pulmona...

    Authors: Keiko Yamamoto, Nobuhiro Tanabe, Yukiko Takahashi, Akira Naito, Ayumi Sekine, Rika Suda, Takayuki Jujo Sanada, Toshihiko Sugiura, Ayako Shigeta, Seiichiro Sakao and Koichiro Tatsumi

    Citation: BMC Pulmonary Medicine 2021 21:260

    Content type: Research

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  11. Tests to identify reversible airflow limitation are important in asthma diagnosis, but they are time-consuming and it may be difficult for patients to cooperate. We aimed to evaluate whether the combination of...

    Authors: Jiang-Hua Li, Rui Han, Yu-Bo Wang, Min Cheng, Heng-Yi Chen, Wen-Hui Lei, Li Li, Chen Gao, Na-Na Zhao, Nai-Fu Nie, Zhong-Yan Li, Guo-Qing Yin, Shuai Huang and Yong He

    Citation: BMC Pulmonary Medicine 2021 21:259

    Content type: Research article

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  12. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common presentation in emergency departments (ED) that can be fatal. This study aimed to develop a mortality risk assessment model for ...

    Authors: Lan Chen, Lijun Chen, Han Zheng, Sunying Wu and Saibin Wang

    Citation: BMC Pulmonary Medicine 2021 21:258

    Content type: Research

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  13. We aim to analyze the risk factors for pneumothorax associated with computed tomography (CT)-guided percutaneous core needle biopsy (PCNB) of the lung. Whether the lung function characteristics are related to ...

    Authors: Chunhai Li, Dexiang Wang, Fengxia Yang, Yang Song, Xuejuan Yu, Bo Liu, Haipeng Jia and Wei Zhou

    Citation: BMC Pulmonary Medicine 2021 21:257

    Content type: Research

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  14. Functional Respiratory Imaging (FRI) combines HRCT scans with computational fluid dynamics to provide objective and quantitative information about lung structure and function. FRI has proven its value in pulmo...

    Authors: Eline Lauwers, Annemiek Snoeckx, Kris Ides, Kim Van Hoorenbeeck, Maarten Lanclus, Wilfried De Backer, Jan De Backer and Stijn Verhulst

    Citation: BMC Pulmonary Medicine 2021 21:256

    Content type: Research article

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  15. Research on health-related quality of life (HRQL) has become increasingly important in recent decades. However, the impact of both living conditions and the level of autonomy impairments on HRQL in COPD patien...

    Authors: Sarah Bettina Schwarz, Tim Mathes, Daniel Sebastian Majorski, Maximilian Wollsching-Strobel, Doreen Kroppen, Friederike Sophie Magnet and Wolfram Windisch

    Citation: BMC Pulmonary Medicine 2021 21:255

    Content type: Research

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  16. Aspiration pneumonitis is an inflammatory disease of the lungs which is difficult to diagnose accurately. Large-volume aspiration of oropharyngeal or gastric contents is essential for the development of aspira...

    Authors: Jiayu Cao, Wei Liu, Li Wang, Yujuan Yang, Yu Zhang and Xicheng Song

    Citation: BMC Pulmonary Medicine 2021 21:254

    Content type: Case report

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  17. Adherence to chronic obstructive pulmonary disease (COPD) maintenance medication is important for managing symptoms and exacerbation risk, and is associated with reduced mortality, hospitalizations, and costs....

    Authors: David Slade, Riju Ray, Chad Moretz, Guillaume Germain, François Laliberté, Qin Shen, Mei Sheng Duh, Malena Mahendran and Beth Hahn

    Citation: BMC Pulmonary Medicine 2021 21:253

    Content type: Research article

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  18. This study aimed to determine the effects of emodin on the viability, proliferation and apoptosis of human pulmonary artery smooth muscle cells (PASMCs) under hypoxia and to explore the underling molecular mec...

    Authors: Li Yi, JunFang Liu, Ming Deng, Huihua Zuo and Mingyan Li

    Citation: BMC Pulmonary Medicine 2021 21:252

    Content type: Research

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  19. Systemic sclerosis (SSc) is a rare disease, and the presence of pulmonary hypertension can be a determining factor in prognosis. The aim of this study was to evaluate the diagnosis, profile, and prognosis of s...

    Authors: Verônica Silva Vilela, Marcio Macri Dias, Ângelo Antunes Salgado, Bruno Rangel Antunes da Silva, Agnaldo José Lopes, Elizabeth Jauhar Cardoso Bessa, Leonardo Palermo Bruno, Cláudia Henrique da Costa, Roger Abramino Levy and Rogério Rufino

    Citation: BMC Pulmonary Medicine 2021 21:251

    Content type: Research article

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  20. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) significantly increases the mortality of patients with COPD. Guidelines have recommended systemic glucocorticoid as a regular treatment. Rec...

    Authors: Qiu-Yu Li, Zhuo-Yu An, Zi-Han Pan and Rui-Ying Qi

    Citation: BMC Pulmonary Medicine 2021 21:250

    Content type: Study protocol

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  21. Treatment for interstitial lung disease (ILD) patients with acute respiratory failure (ARF) is challenging, and literature to guide such treatment is scarce. The reported in-hospital mortality rates of ILD pat...

    Authors: Johanna P. van Gemert, Inge A. H. van den Berk, Esther J. Nossent, Leo M. A. Heunks, Rene E. Jonkers, Alexander P. Vlaar and Peter I. Bonta

    Citation: BMC Pulmonary Medicine 2021 21:249

    Content type: Research article

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  22. Authors: Benoît Misset, Eric Hoste, Anne Françoise Donneau, David Grimaldi, Geert Meyfroidt, Michel Moutschen, Veerle Compernolle, André Gothot, Daniel Desmecht, Mutien Garigliany, Tome Najdovski and Pierre François Laterre

    Citation: BMC Pulmonary Medicine 2021 21:248

    Content type: Correction

    Published on:

    The original article was published in BMC Pulmonary Medicine 2020 20:317

  23. Long non-coding RNAs (lncRNAs) play important roles in the development of pneumonia. We aimed to explore the role of the lncRNA KCNQ1OT1 in pneumonia and its underlying mechanisms.

    Authors: Ping Wang, Haitao Zhang, Weiqing Zhao and Nini Dai

    Citation: BMC Pulmonary Medicine 2021 21:247

    Content type: Research

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  24. Observational studies show an association between reduced lung function and impaired cognition. Cognitive dysfunction influences important health outcomes and is a precursor to dementia, but treatments options...

    Authors: Daniel H. Higbee, Raquel Granell, Gibran Hemani, George Davey Smith and James W. Dodd

    Citation: BMC Pulmonary Medicine 2021 21:246

    Content type: Research

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  25. Nintedanib reduces the rate of decline in forced vital capacity in patients with idiopathic pulmonary fibrosis (IPF), other chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype and ...

    Authors: Ulrike Schmid, Benjamin Weber, Celine Sarr and Matthias Freiwald

    Citation: BMC Pulmonary Medicine 2021 21:244

    Content type: Research

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  26. Fibrotic hypersensitivity pneumonitis (HP) is a chronic interstitial lung disease caused by allergic responses to repeated exposures to a causative antigen. Therapeutic evidence of the use of corticosteroids t...

    Authors: Masaru Ejima, Tsukasa Okamoto, Takafumi Suzuki, Tatsuhiko Anzai, Kunihiko Takahashi and Yasunari Miyazaki

    Citation: BMC Pulmonary Medicine 2021 21:243

    Content type: Research article

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  27. Lung adenocarcinoma (LUAD) is one of the most common cancers with high morbidity and mortality worldwide. Long non-coding RNAs (lncRNAs) serve as tumor promoters or suppressors in the development of various hu...

    Authors: Ye Qian, Yan Zhang, Haoming Ji, Yucheng Shen, Liangfeng Zheng, Shouliang Cheng and Xiaomin Lu

    Citation: BMC Pulmonary Medicine 2021 21:242

    Content type: Research article

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  28. The novel coronavirus SARS-Cov-2 can infect the respiratory tract causing a spectrum of disease varying from mild to fatal pneumonia, and known as COVID-19. Ongoing clinical research is assessing the potential...

    Authors: Francesco Lombardi, Angelo Calabrese, Bruno Iovene, Chiara Pierandrei, Marialessia Lerede, Francesco Varone, Luca Richeldi and Giacomo Sgalla

    Citation: BMC Pulmonary Medicine 2021 21:241

    Content type: Research

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  29. Partnership between anesthesia providers and proceduralists is essential to ensure patient safety and optimize outcomes. A renewed importance of this axiom has emerged in advanced bronchoscopy and intervention...

    Authors: Michael A. Pritchett, Kelvin Lau, Scott Skibo, Karen A. Phillips and Krish Bhadra

    Citation: BMC Pulmonary Medicine 2021 21:240

    Content type: Review

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  30. Idiopathic Pulmonary Fibrosis is a chronic, progressive interstitial lung disease for which there is no cure. However, lung function decline, hospitalizations, and mortality may be reduced with the use of the ...

    Authors: Bryan T. Kelly, Viengneesee Thao, Timothy M. Dempsey, Lindsey R. Sangaralingham, Stephanie R. Payne, Taylor T. Teague, Teng Moua, Nilay D. Shah and Andrew H. Limper

    Citation: BMC Pulmonary Medicine 2021 21:239

    Content type: Research

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  31. Pain is a common but underappreciated symptom experienced by people with Chronic Obstructive Pulmonary Disease (COPD). The relationships between pain and physical activity (PA) and exercise capacity are poorly...

    Authors: Rebecca A. Raphaely, Maria A. Mongiardo, Rebekah L. Goldstein, Stephanie A. Robinson, Emily S. Wan and Marilyn L. Moy

    Citation: BMC Pulmonary Medicine 2021 21:238

    Content type: Research

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  32. The mortality risk of chronic interstitial lung disease (ILD) is currently assessed using the ILD-GAP score. The present study evaluates whether the addition of cardiopulmonary ultrasound parameters to the ILD...

    Authors: Wei-wei Zhu, Hong Li, Yi-dan Li, Lanlan Sun, Lingyun Kong, Xiaoguang Ye, Qizhe Cai and Xiu-zhang Lv

    Citation: BMC Pulmonary Medicine 2021 21:237

    Content type: Research

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  33. Acute lung injury (ALI) is a pulmonary disorder that leads to acute respiration failure and thereby results in a high mortality worldwide. Increasing studies have indicated that toll-like receptor 4 (TLR4) is ...

    Authors: Qingsong Sun, Man Luo, Zhiwei Gao, Xiang Han, Weiqin Wu and Hongmei Zhao

    Citation: BMC Pulmonary Medicine 2021 21:236

    Content type: Research

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  34. Secondary polycythemia is associated with cigarette smoking and chronic obstructive pulmonary disease (COPD). However, the prevalence of polycythemia in COPD and the contributing risk factors for polycythemia ...

    Authors: Jingzhou Zhang, Dawn L. DeMeo, Edwin K. Silverman, Barry J. Make, R. Chad Wade, J. Michael Wells, Michael H. Cho and Brian D. Hobbs

    Citation: BMC Pulmonary Medicine 2021 21:235

    Content type: Research article

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  35. Non-small cell lung cancer (NSCLC) is one of the most prevalent cancers. As reported, long non-coding RNAs (lncRNAs) induce various biological behaviors in cancers. LncRNA PCGEM1 prostate-specific transcript (...

    Authors: Huanshun Wen, Hongxiang Feng, Qianli Ma and Chaoyang Liang

    Citation: BMC Pulmonary Medicine 2021 21:234

    Content type: Research

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  36. To explore the long-term trajectories considering pneumonia volumes and lymphocyte counts with individual data in COVID-19.

    Authors: Nannan Shi, Chao Huang, Qi Zhang, Chunzi Shi, Fengjun Liu, Fengxiang Song, Qinguo Hou, Jie Shen, Fei Shan, Xiaoming Su, Cheng Liu, Zhiyong Zhang, Lei Shi and Yuxin Shi

    Citation: BMC Pulmonary Medicine 2021 21:233

    Content type: Research

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  37. Few reference equations exist for healthy adults of various races for pulmonary diffusing capacity for nitric oxide (DLNO). The purpose of this study was to collect pilot data to demonstrate that race-specific...

    Authors: Gerald Stanley Zavorsky, Ahmad Saleh Almamary, Mobarak Khalid Alqahtani, Shi Huh Samuel Shan and Douglas Shawn Gardenhire

    Citation: BMC Pulmonary Medicine 2021 21:232

    Content type: Research

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  38. The association between the dual use of electronic cigarette (e-cigarette) and conventional cigarettes (c-cigarette) and spirometry-defined chronic obstructive pulmonary disease (COPD) has not been studied tho...

    Authors: Taeyun Kim and Jihun Kang

    Citation: BMC Pulmonary Medicine 2021 21:231

    Content type: Research

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  39. The life-threatening haemorrhagic complications of pulmonary arteriovenous malformations (PAVMs) are extremely rare, and only described in isolated cases. This study was designed to comprehensively investigate...

    Authors: Xu Ma, Bing Jie, Dong Yu, Ling-Ling Li and Sen Jiang

    Citation: BMC Pulmonary Medicine 2021 21:230

    Content type: Research

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  40. The SARS-CoV2 pandemic increased exponentially the need for both Intensive (ICU) and Intermediate Care Units (RICU). The latter are of particular importance because they can play a dual role in critical and po...

    Authors: Mónica Matute-Villacís, Jorge Moisés, Cristina Embid, Judith Armas, Isabel Fernández, Montserrat Medina, Miquel Ferrer, Oriol Sibila and Joan Ramón Badia

    Citation: BMC Pulmonary Medicine 2021 21:228

    Content type: Research

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  41. Medical thoracoscopy (MT) is recommended in patients with undiagnosed exudative pleural effusion and offers a degree of diagnostic sensitivity for pleural malignancy. However, not all patients who undergo MT r...

    Authors: Yan-Xia Yu, Yuan Yang, Yan-Bing Wu, Xiao-Juan Wang, Li-Li Xu, Zhen Wang, Feng Wang, Zhao-Hui Tong and Huan-Zhong Shi

    Citation: BMC Pulmonary Medicine 2021 21:226

    Content type: Research

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  42. Cystic fibrosis (CF) is a life-threatening multiorgan genetic disease, particularly affecting the lungs, where recurrent infections are the main cause of reduced life expectancy. In CF, mutations in the gene e...

    Authors: Mária Budai-Szűcs, Szilvia Berkó, Anita Kovács, Pongsiri Jaikumpun, Rita Ambrus, Adrien Halász, Piroska Szabó-Révész, Erzsébet Csányi and Ákos Zsembery

    Citation: BMC Pulmonary Medicine 2021 21:225

    Content type: Research

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  43. To evaluate the accuracy and safety of contrast-enhanced ultrasound (CEUS) guided biopsy in the diagnosis of radiologically determined pleural based lesions.

    Authors: Wenwen Sun, Yiming Zhou, Cong Yang, Zhengwei Dong, ZheMin Zhang, Yin Wang and Lin Fan

    Citation: BMC Pulmonary Medicine 2021 21:224

    Content type: Research

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  44. Ciliated muconodular papillary tumor (CMPT) is an incredibly rare pulmonary tumor. Currently, little is known about CMPT, and it has not yet been classified by the World Health Organization. The clinical manif...

    Authors: Lei Zhao, Conner M. Willson, Nathan T. Givens, Ziwen Zhu, Mark R. Wakefield, Yongsheng Wang, Wanchun Yang and Yujiang Fang

    Citation: BMC Pulmonary Medicine 2021 21:223

    Content type: Case report

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  45. Endobronchial electrocautery is a common and safe therapeutic endoscopic treatment for malignant airway obstruction. Cerebral arterial air embolism (CAAE) is a rare but potentially fatal complication of endobr...

    Authors: Yu-Ping He, Yuan-Ling Liu, Xing-Lin Gao and Li-Hua Wang

    Citation: BMC Pulmonary Medicine 2021 21:222

    Content type: Case report

    Published on:

  46. Currently, there are two antifibrotics used to treat idiopathic pulmonary fibrosis (IPF): pirfenidone and nintedanib. Antifibrotics slow disease progression by reducing the annual decline of forced vital capac...

    Authors: Yuzo Suzuki, Kazutaka Mori, Yuya Aono, Masato Kono, Hirotsugu Hasegawa, Koshi Yokomura, Hyogo Naoi, Hironao Hozumi, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Naoki Inui, Hidenori Nakamura and Takafumi Suda

    Citation: BMC Pulmonary Medicine 2021 21:221

    Content type: Research

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