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  1. With the growing practice of home mechanical ventilation, there is a need to identify biological markers for adequate follow-up. Red cell distribution width (RDW) is a promising candidate because it is conveni...

    Authors: Luca Valko, Szabolcs Baglyas, Eszter Podmaniczky, Zoltan Prohaszka, Janos Gal and Andras Lorx
    Citation: BMC Pulmonary Medicine 2022 22:115
  2. Lung adenocarcinoma accounts for approximately 40% of all primary lung cancers; however, the mortality rates remain high. Successfully predicting progression and overall (OS) time will provide clinicians with ...

    Authors: Jing Sun, Yan Yan, Yiming Meng, Yushu Ma, Tianzhao Du, Tao Yu and Haozhe Piao
    Citation: BMC Pulmonary Medicine 2022 22:114
  3. Authors: Sergey Udalov, Rio Dumitrascu, Soni Savai Pullamsetti, Hamza M. Al-tamari, Norbert Weissmann, Hossein Ardeschir Ghofrani, Andreas Guenther, Robert Voswinckel, Werner Seeger, Friedrich Grimminger and Ralph T. Schermuly
    Citation: BMC Pulmonary Medicine 2022 22:113

    The original article was published in BMC Pulmonary Medicine 2010 10:26

  4. This study aims to evaluate the diagnostic application and performance of the metagenomic next-generation sequencing (mNGS) in patients suspected of local pulmonary infection by comparing it to the traditional...

    Authors: Shan-shan Su, Xue-bing Chen, Ling-ping Zhou, Peng-cheng Lin, Jun-jie Chen, Cheng-shui Chen, Qing Wu, Jun-ru Ye and Yu-ping Li
    Citation: BMC Pulmonary Medicine 2022 22:112
  5. The zinc transporter ZIP12 is a membrane-spanning protein that transports zinc ions into the cytoplasm from the extracellular space. Recent studies demonstrated that upregulation of ZIP12 is involved in elevat...

    Authors: Chaoyi Ye, Guili Lian, Tingjun Wang, Ai Chen, Weixiao Chen, Jin Gong, Li Luo, Huajun Wang and Liangdi Xie
    Citation: BMC Pulmonary Medicine 2022 22:111
  6. Variability in triazole plasma concentrations by drug interactions is well known. An interaction between voriconazole and flucloxacillin has already been described. In our case we observed a similar interactio...

    Authors: Saartje Verfaillie, Laurent Godinas, Isabel Spriet, Robin Vos and Geert M. Verleden
    Citation: BMC Pulmonary Medicine 2022 22:110
  7. A previous study showed that the lungs are involved in the biogenesis of platelets (PLTs). Thus, the present study aimed to investigate the association between bronchopulmonary dysplasia (BPD), a chronic lung ...

    Authors: Xiaoling Wang, Yan Ma, Shenghui Wang, Wenbin Dong and Xiaoping Lei
    Citation: BMC Pulmonary Medicine 2022 22:109
  8. The clinical treatment of patients suspected of pulmonary infections often rely on empirical antibiotics. However, preliminary diagnoses were based on clinical manifestations and conventional microbiological t...

    Authors: Ping Wei, Yang Gao, Jing Zhang, Jianlong Lin, Huibin Liu, Keqiang Chen, Weikai Lin, Xiaojia Wang, Chune Wang and Chao Liu
    Citation: BMC Pulmonary Medicine 2022 22:108
  9. Neutrophilic inflammation in the airway is a hallmark of bronchiectasis. Neutrophil extracellular traps (NETs) have been reported to play an important role in the occurrence and development of bronchiectasis. ...

    Authors: Shiqi Li, Chunxiao Yu, Hongyu Jie, Xinai Han, Shujing Zou, Quanguang Tan, Shugeng Luo, Youming Chen and Jinhong Wang
    Citation: BMC Pulmonary Medicine 2022 22:107
  10. Chronic Obstructive Pulmonary Disease (COPD) is characterized by progressive and irreversible airflow limitation. Different factors that modify pulmonary function include age, sex, muscular strength, and a his...

    Authors: Nathalie Martínez-Luna, Arturo Orea-Tejeda, Dulce González-Islas, Laura Flores-Cisneros, Candace Keirns-Davis, Rocío Sánchez-Santillán, Ilse Pérez-García, Yael Gastelum-Ayala, Valeria Martínez-Vázquez and Óscar Martínez-Reyna
    Citation: BMC Pulmonary Medicine 2022 22:106
  11. Pulmonary Arterial Hypertension (PAH) is a rare, debilitating, and potentially fatal disease. This study aims to quantify the economic burden of PAH in Spain.

    Authors: Néboa Zozaya, Fernando Abdalla, Ignacio Casado Moreno, Carlos Crespo-Diz, Ana M. Ramírez Gallardo, Joaquín Rueda Soriano, Macarena Alcalá Galán and Álvaro Hidalgo-Vega
    Citation: BMC Pulmonary Medicine 2022 22:105
  12. The study objective was to investigate the use of peripheral blood biomarkers as predictors of patient survival. The aim of this study was to identify the baseline peripheral blood biomarkers associated with c...

    Authors: Jun Wang, Huawei li, Ran Xu, Tong Lu, Jiaying Zhao, Pengfei Zhang, Lidong Qu, Shengqiang Zhang, Jida Guo and Linyou Zhang
    Citation: BMC Pulmonary Medicine 2022 22:104
  13. Obesity is a risk factor for dyspnea. However, investigations of daily living obesity-related dyspnea are limited and its mechanisms remain unclear. We conducted a cross-sectional study to analyze the relation...

    Authors: Jean Hagenburg, Eric Bertin, Jean-Hugues Salmon, Aurore Thierry, Jeanne-Marie Perotin, Valérian Dormoy, Sandra Dury, Isabelle Gaubil, Lois Bolko, François Lebargy, Gaëtan Deslee and Claire Launois
    Citation: BMC Pulmonary Medicine 2022 22:103
  14. The 6-min walk test (6MWT) and incremental shuttle walk test (ISWT) are valid and reliable measures to assess exercise capacity of patients with chronic obstructive pulmonary disease (COPD). However, the compa...

    Authors: Ganghee Chae, Eun Jae Ko, Sei Won Lee, Hyun Jung Kim, Sang Gyu Kwak, Donghwi Park and Seung Won Ra
    Citation: BMC Pulmonary Medicine 2022 22:102
  15. In Germany, the first case of coronavirus disease 2019 (COVID-19) was registered on 28 January 2020. By February 2021, the third wave of the pandemic began. So far, only few data are available on the SARS-CoV-...

    Authors: Anke Jaudszus, Mariya Pavlova, Marius Rasche, Michael Baier, Anne Moeser and Michael Lorenz
    Citation: BMC Pulmonary Medicine 2022 22:101
  16. The reference values for lung function are associated to anatomical and lung morphology parameters, but anthropometry it is not the only influencing factor: altitude and genetics are two important agents affec...

    Authors: Esteban Ortiz-Prado, Sebastián Encalada, Johanna Mosquera, Katherine Simbaña-Rivera, Lenin Gomez-Barreno, Diego Duta, Israel Ochoa, Juan S. Izquierdo-Condoy, Eduardo Vasconez, German Burgos, Manuel Calvopiña and Ginés Viscor
    Citation: BMC Pulmonary Medicine 2022 22:100
  17. Most patients with comorbid sleep apnea (OSA), cardiovascular (CV) disease, and/or cerebrovascular (CeV) disease simultaneously take medications. Whether OSA and continuous positive airway pressure (CPAP) inte...

    Authors: Miaochan Lao, Yilu Cheng, Xinglin Gao and Qiong Ou
    Citation: BMC Pulmonary Medicine 2022 22:99
  18. Medication adherence in chronic obstructive pulmonary disease (COPD) is low, though not enough is known about the factors that affect adherence in COPD. This study uses qualitative methods to understand the pa...

    Authors: Jacqueline O’Toole, Meera Krishnan, Kristin Riekert and Michelle N. Eakin
    Citation: BMC Pulmonary Medicine 2022 22:98
  19. Neuromuscular pathologies must be considered when caring for patients with persistent or progressive respiratory failure. Pertinent disease states may involve skeletal muscles of respiration or associated neur...

    Authors: Pradhab Kirupaharan, Daniel Kramer, Alan Gandler, Lawrence Kenyon and Ross Summer
    Citation: BMC Pulmonary Medicine 2022 22:97
  20. Elderly people are more likely to suffer severe chronic obstructive pulmonary disease (COPD) and require long-term home oxygen therapy (LTOT) as part of their treatment. LTOT has advantages such as improvement...

    Authors: Giovanna Hass Bueno, Claudinei José Gomes Campos, Egberto Ribeiro Turato, Ilma Aparecida Paschoal, Lucas Serra Valladão, Leticia Baltieri and Luiz Cláudio Martins
    Citation: BMC Pulmonary Medicine 2022 22:96
  21. Lung ultrasound (LUS) is a useful tool for assessing the severity of lung disease, without radiation exposure. However, there is little data on the practicality of LUS in assessing the severity of bronchopulmo...

    Authors: Ying-Hua Sun, Yang Du, Jie-Ru Shen, Dan-Yang Ai, Xiang-Yuan Huang, Si-Hao Diao, Sam Bill Lin, Rong Zhang, Lin Yuan, Yi-Pei Yang, Li-Li He, Xiao-Jiao Qin, Jian-Guo Zhou and Chao Chen
    Citation: BMC Pulmonary Medicine 2022 22:95
  22. Although some evidence suggests an association between obstructive sleep apnea (OSA) and gestational diabetes mellitus (GDM), its consequences still remain largely unknown. We sought to determine whether OSA i...

    Authors: Oleksandr Serednytskyy, Alberto Alonso-Fernández, Caterina Ribot, Andrea Herranz, Ainhoa Álvarez, Andrés Sánchez, Paula Rodríguez, Ana V. Gil, Carla Pía, José P. Cubero, María Barceló, María Cerdà, Mercedes Codina, Mónica D. Peña, Antònia Barceló, Amanda Iglesias…
    Citation: BMC Pulmonary Medicine 2022 22:94
  23. Not being able to work has negative health, social and financial consequences. Persisting breathlessness is prevalent in working-aged people. Is it associated with lower workforce participation? This study, us...

    Authors: Joseph Clark, Sungwon Chang, Irina Kinchin, Diana Ferreira, Slavica Kochovska, Deidre Morgan, Leanne M. Poulos, Miriam J. Johnson, Magnus Ekström and David C. Currow
    Citation: BMC Pulmonary Medicine 2022 22:93
  24. First Nations children hospitalised with acute lower respiratory infections (ALRIs) are at increased risk of future bronchiectasis (up to 15–19%) within 24-months post-hospitalisation. An identified predictive...

    Authors: André Schultz, Anne B. Chang, Fenella Gill, Roz Walker, Melanie Barwick, Sarah Munns, Matthew N. Cooper, Richard Norman and Pamela Laird
    Citation: BMC Pulmonary Medicine 2022 22:92
  25. Data on changes in lung function in eosinophilic chronic obstructive pulmonary disease (COPD) are limited. We investigated the longitudinal changes in forced expiratory volume in 1 s (FEV1) and effects of inhaled...

    Authors: Yong Suk Jo, Ji-Yong Moon, Yong Bum Park, Yee Hyung Kim, Soo-Jung Um, Woo Jin Kim, Hyoung Kyu Yoon, Kwang Ha Yoo, Ki-Suck Jung and Chin Kook Rhee
    Citation: BMC Pulmonary Medicine 2022 22:91
  26. Mucus production is a process involved in the pathogenesis of Community-acquired pneumonia (CAP). The study is to determine Mucin 5B (MUC5B) protein concentration and its proportion in the bronchoalveolar lava...

    Authors: Lu Fan, Yi Lu, Yan Wang, Xiaomin Zhang, Yuxuan Wu, Hao Sun and Jinsong Zhang
    Citation: BMC Pulmonary Medicine 2022 22:90
  27. Intrapulmonary arteriovenous shunts is rare seen in a patient without lung involvement.

    Authors: Huan Hou, Cuiyan Guo, Chengli Que, Ligong Nie, Qi Zhang, Hong Zhao, Lin Nong, Wei Ma, Qian Wang, Zeyin Liang, Bingjie Wang, Jing Ma and Guangfa Wang
    Citation: BMC Pulmonary Medicine 2022 22:89
  28. Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory tract infection in infants. Globally, RSV is responsible for approximately 3.2 million hospital admissions and about 60,000...

    Authors: Martin Wetzke, Dominik Funken, Mathias Lange, Levente Bejo, Sibylle Haid, Joao G. Tereno Monteiro, Katharina Schütz, Christine Happle, Thomas F. Schulz, Jürgen Seidenberg, Thomas Pietschmann and Gesine Hansen
    Citation: BMC Pulmonary Medicine 2022 22:88
  29. Dexmedetomidine (DEX), is a highly selective alpha2 adrenoceptor (α2-AR) agonist, successfully used in various procedures including flexible bronchoscopy. Randomized controlled trials (RCTs) evaluating DEX sed...

    Authors: Barak Pertzov, Boris Krasulya, Karam Azem, Yael Shostak, Shimon Izhakian, Dror Rosengarten, Svetlana kharchenko and Mordechai R. Kramer
    Citation: BMC Pulmonary Medicine 2022 22:87
  30. Baculoviral IAP repeat-containing 3 (BIRC3) which encodes a member of the IAP family of proteins upregulated in the asthma expression profile dataset. However, there was few research on studying the clinical i...

    Authors: Lijuan Du, Changyi Xu, Zhimin Zeng, Fengjia Chen, Kun Tang, Yuxia Liang and Yubiao Guo
    Citation: BMC Pulmonary Medicine 2022 22:86
  31. Severe asthma exacerbation reduces patients’ quality of life, results in visits to the emergency department (ED) and hospitalization, and incurs additional medical costs. Antipsychotics block receptors with br...

    Authors: Chin-Wei Kuo, Szu-Chun Yang, Yu-Fen Shih, Xin-Min Liao and Sheng-Hsiang Lin
    Citation: BMC Pulmonary Medicine 2022 22:85
  32. Prisoners in low- and middle-income countries are vulnerable to poor lung health from multiple adverse conditions confronted within the prison such as overcrowding, poor ventilation and exposure to second hand...

    Authors: Joy Nkiru Eze, Obianuju Beatrice Ozoh, Fred Chibuisi Otuu, Elvis Neba Shu and Bond Ugochukwu Anyaehie
    Citation: BMC Pulmonary Medicine 2022 22:84
  33. Glycemic variability (GV) has only been sparsely studied in patients with community-acquired pneumonia (CAP). This study aimed to quantify in-hospital GV in CAP patients, including determining the impact of ty...

    Authors: Mikkel Thor Olsen, Arnold Matovu Dungu, Carina Kirstine Klarskov, Andreas Kryger Jensen, Birgitte Lindegaard and Peter Lommer Kristensen
    Citation: BMC Pulmonary Medicine 2022 22:83
  34. The lack of simple and affordable spirometry has led to the missed and delayed diagnoses of chronic respiratory diseases in communities. The PUS201P is a portable spirometry developed to solve this problem.

    Authors: Shan Xiao, Fan Wu, Zihui Wang, Jianmin Chen, Huajing Yang, Youlan Zheng, Zhishan Deng, Jieqi Peng, Xiang Wen, Peiyu Huang, Cuiqiong Dai, Lifei Lu, Ningning Zhao, Pixin Ran and Yumin Zhou
    Citation: BMC Pulmonary Medicine 2022 22:80
  35. Bronchoalveolar lavage (BAL) is a major diagnostic tool in interstitial lung disease (ILD). Its use remains largely quantitative, usually focused on cell differential ratio. However, cellular morphological fea...

    Authors: Antoine Moui, Stéphanie Dirou, Christine Sagan, Renan Liberge, Claire Defrance, Pierre-Paul Arrigoni, Olivier Morla, Christine Kandel-Aznar, Laurent Cellerin, Arnaud Cavailles, Emmanuel Eschapasse, Florent Morio, Pierre-Antoine Gourraud, Thomas Goronflot, Adrien Tissot and François-Xavier Blanc
    Citation: BMC Pulmonary Medicine 2022 22:79
  36. Rats with chronic hypoxia-induced non-inflammatory pulmonary hypertension (PH) are resistant to ventilator-induced lung injury. We investigated the effect of high tidal volume ventilation in another model of P...

    Authors: Masako Kawai, Erquan Zhang, Jane Chanda Kabwe, Amphone Okada, Junko Maruyama, Hirofumi Sawada and Kazuo Maruyama
    Citation: BMC Pulmonary Medicine 2022 22:78
  37. Multifocal micronodular pneumocyte hyperplasia (MMPH) is a rare pulmonary manifestation of the tuberous sclerosis complex (TSC) with distinctive histological characteristics. Most case reports of MMPH associat...

    Authors: Shan Li, Chaojie Wu, Qiyun Ma, Xueqin Chen, Wei Zhang, Xiao Li, Mao Huang and Ningfei Ji
    Citation: BMC Pulmonary Medicine 2022 22:77
  38. Centrilobular nodules, ground-glass opacity (GGO), mosaic attenuation, air trapping, and three-density pattern were reported as high-resolution computed tomography (HRCT) findings characteristic of fibrotic hy...

    Authors: Hiroko Okabayashi, Taiki Fukuda, Tae Iwasawa, Tsuneyuki Oda, Hideya Kitamura, Tomohisa Baba, Tamiko Takemura, Takuro Sakagami and Takashi Ogura
    Citation: BMC Pulmonary Medicine 2022 22:76
  39. The systemic immune-inflammation index (SII) has recently emerged as a predictor of survival in non-small cell lung cancer patients. There is also tight correlation between radiotherapy and immune status, and ...

    Authors: Qi Wang, Xiaojing Tan, Guangchuan Deng, Shuai Fu, Jianbin Li and Zhenxiang Li
    Citation: BMC Pulmonary Medicine 2022 22:75
  40. Individuals with low socioeconomic status experience higher prevalence and worse outcomes of chronic obstructive pulmonary disease (COPD). We undertook a quality improvement initiative at our safety net hospit...

    Authors: Lauren Kearney, Renda Soylemez Wiener, Mohsin Dahodwala, Gemmae M. Fix, Jacqueline Hicks, Frederic Little, Jinesa Howard, Alexis Gallardo Foreman, Cornelia Wakeman, Charles O’Donnell, Katia Bulekova, Mari-Lynn Drainoni and Hasmeena Kathuria
    Citation: BMC Pulmonary Medicine 2022 22:74
  41. Interstitial lung disease (ILD) may cause life-threatening complications of primary Sjogren’s syndrome (pSS), and has a poor prognosis in terms of survival and quality of life. To date, few studies have invest...

    Authors: Wei Lin, Zhifei Xin, Jianlong Zhang, Ning Liu, Xiuying Ren, Meilu Liu, Yashuang Su, Yixuan Liu, Liu Yang, Shaoying Guo, Yupeng Yang, Yang Li, Jingjing Cao, Xiaoran Ning, Jingjing Li, He Xue…
    Citation: BMC Pulmonary Medicine 2022 22:73
  42. High altitude pulmonary edema (HAPE) is a hypoxia-induced non-cardiogenic pulmonary edema that typically occurred in un-acclimatized lowlanders, which inevitably leads to life-threatening consequences. Apart f...

    Authors: Yan Wang, Xuewen Huang, Fujun Peng, Huiling Han, Yanan Gu, Xin Liu and Zhichun Feng
    Citation: BMC Pulmonary Medicine 2022 22:72
  43. Prone positioning enables the redistribution of lung weight, leading to the improvement of gas exchange and respiratory mechanics. We aimed to evaluate whether the initial findings of acute respiratory distres...

    Authors: You-Yi Chen, Jerry Shu-Hung Kuo, Sheng-Yuan Ruan, Ying-Chun Chien, Shih-Chi Ku, Chong-Jen Yu and Jung-Yien Chien
    Citation: BMC Pulmonary Medicine 2022 22:71
  44. Asthma is a common airways disease with significant morbidity and mortality in all ages. Studies of pediatric asthma control and its determinants yielded variable results across settings. However, there is pau...

    Authors: Amare Aschalew, Rahel Argaw Kebed, Takele Gezahegn Demie and Abate Yeshidinber Weldetsadik
    Citation: BMC Pulmonary Medicine 2022 22:70
  45. Chronic bronchitis (CB) is associated with poor outcomes in patients with chronic obstructive pulmonary disease. The aim of this study was to identify the characteristics that distinguish chronic bronchitis (C...

    Authors: Joon Young Choi, Hyoung Kyu Yoon, Sang Yeub Lee, Jin Woo Kim, Hye Sook Choi, Yu-Il Kim, Ki-Suck Jung, Kwang Ha Yoo, Woo Jin Kim and Chin Kook Rhee
    Citation: BMC Pulmonary Medicine 2022 22:69
  46. Central airway obstruction (CAO) represents a pathological condition that can lead to airflow limitation of the trachea, main stem bronchi, bronchus intermedius or lobar bronchus.

    Authors: Fernando Guedes, Mariana V. Branquinho, Ana C. Sousa, Rui D. Alvites, António Bugalho and Ana Colette Maurício
    Citation: BMC Pulmonary Medicine 2022 22:68
  47. To evaluate the effects of doxofylline on inflammatory responses and oxidative stress during mechanical ventilation in rats with chronic obstructive pulmonary disease (COPD).

    Authors: Zhi-yuan Chen, Yu-mei Lin, Jian-hua Wu, Xiao-qi Zhang, Yi Zhang, Wen-xi Xie, Shu-qiang Chu and Yan Li
    Citation: BMC Pulmonary Medicine 2022 22:66
  48. Chronic obstructive pulmonary disease (COPD) decreases quality of life and muscular strength. Inspiratory flow is important for inhalants in the bronchi but is complicated to measure in routine practice. We hy...

    Authors: Takahiro Tsuburai, Yuko Komase, Hajime Tsuruoka, Baku Oyama, Hiromi Muraoka, Naoya Hida, Takayuki Kobayashi and Shinya Matsushima
    Citation: BMC Pulmonary Medicine 2022 22:65

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