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  1. Serious inhaler technique errors can impair drug delivery to the lungs. This randomised, crossover, open-label study evaluated the proportion of patients making predefined serious errors with Pulmojet compared...

    Authors: Henry Chrystyn, David B. Price, Mathieu Molimard, John Haughney, Sinthia Bosnic-Anticevich, Federico Lavorini, John Efthimiou, Dawn Shan, Erika Sims, Anne Burden, Catherine Hutton and Nicolas Roche
    Citation: BMC Pulmonary Medicine 2016 16:12
    Content type: Research article Published on:

  2. The prevalence of asthma and other allergic diseases among children living in Eastern is not well described. Our objective was to estimate and compare the prevalence of asthma, respiratory symptoms and allergi...

    Authors: Grzegorz Brozek, Joshua Lawson, Andrei Shpakou, Olga Fedortsiv, Leonid Hryshchuk, Donna Rennie and Jan Zejda
    Citation: BMC Pulmonary Medicine 2016 16:11
    Content type: Research article Published on:

  4. As-needed formoterol can effectively relieve asthma symptoms. Since budesonide/formoterol is available as maintenance and reliever therapy in Asia, formoterol is now being used as-needed, but always with conco...

    Authors: Qi Jian Cheng, Shao-Guang Huang, Yu Zhi Chen, Jiang-Tao Lin, Xin Zhou, Bao-Yuan Chen, Yu-Lin Feng, Xia Ling and Malcolm R. Sears
    Citation: BMC Pulmonary Medicine 2016 16:8
    Content type: Research article Published on:

  5. Idiopathic pulmonary fibrosis (IPF) is a form of chronic fibrosing interstitial pneumonia characterized by progressive worsening of dyspnea and lung function, with a poor prognosis. The objective of this study...

    Authors: Ferran Morell, Dirk Esser, Jonathan Lim, Susanne Stowasser, Alba Villacampa, Diana Nieves and Max Brosa
    Citation: BMC Pulmonary Medicine 2016 16:7
    Content type: Research article Published on:

  6. Release of ambient metals during ferroalloy production may be an important source of environmental exposure for nearby communities and exposure to these metals has been linked to adverse respiratory outcomes. ...

    Authors: Maria José Rosa, Chiara Benedetti, Marco Peli, Filippo Donna, Marco Nazzaro, Chiara Fedrighi, Silvia Zoni, Alessandro Marcon, Neil Zimmerman, Rosalind Wright and Roberto Lucchini
    Citation: BMC Pulmonary Medicine 2016 16:6
    Content type: Research article Published on:

  7. Combination therapy is frequently used to treat patients with pulmonary hypertension but few studies have compared treatment regimens. This study examined the long-term effect of different combination regimens...

    Authors: Henning Gall, Natascha Sommer, Katrin Milger, Manuel J. Richter, Robert Voswinckel, Dirk Bandorski, Werner Seeger, Friedrich Grimminger and Hossein-Ardeschir Ghofrani
    Citation: BMC Pulmonary Medicine 2016 16:5
    Content type: Research article Published on:

  8. Pulmonary fibrosis (PF) is a rare, progressive disease that affects patients and their loved ones on many levels. We sought to better understand the needs and interests of PF patients and their loved ones (col...

    Authors: Karen Albright, Tarik Walker, Susan Baird, Linda Eres, Tara Farnsworth, Kaitlin Fier, Dolly Kervitsky, Marjorie Korn, David J. Lederer, Mark McCormick, John F. Steiner, Thomas Vierzba, Frederick S. Wamboldt and Jeffrey J. Swigris
    Citation: BMC Pulmonary Medicine 2016 16:4
    Content type: Research article Published on:

  9. Omalizumab (Xolair®), a recombinant monoclonal anti-IgE antibody, has demonstrated efficacy in clinical trials conducted in patients with moderate to severe persistent allergic asthma. We aimed to investigate ...

    Authors: Hao-Cheng Chen, Chien-Da Huang, Erin Chang and Han-Pin Kuo
    Citation: BMC Pulmonary Medicine 2016 16:3
    Content type: Research article Published on:

  10. Idiopathic pulmonary fibrosis (IPF) is a devastating condition with a variable course. Not uncommonly, IPF patients are hospitalized for respiratory-related causes, including disease worsening. This study aime...

    Authors: Karina Raimundo, Eunice Chang, Michael S. Broder, Kimberly Alexander, James Zazzali and Jeffrey J. Swigris
    Citation: BMC Pulmonary Medicine 2016 16:2
    Content type: Research article Published on:

  11. Influenza B virus infection is generally considered to be mild and is rarely associated pulmonary cardiovascular involvement in adults. However fatal complications may occur.

    Authors: Hsu-Liang Chang, Jui-Feng Hsu, Ying-Ming Tsai, Shang-Yi Lin, Hsuan-Fu Kuo and Chih-Jen Yang
    Citation: BMC Pulmonary Medicine 2016 16:1
    Content type: Case report Published on:

  12. Idiopathic pulmonary fibrosis (IPF) is a rare and serious disease characterized by progressive lung-function loss. Limited evidence has been published on the impact of lung-function loss on subsequent patient ...

    Authors: William M. Reichmann, Yanni F. Yu, Dendy Macaulay, Eric Q. Wu and Steven D. Nathan
    Citation: BMC Pulmonary Medicine 2015 15:167
    Content type: Research article Published on:

  13. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is widely used to perform mediastinal lymph node sampling. However, little information is available on polymerase chain reaction for My...

    Authors: Jung Seop Eom, Jeong Ha Mok, Min Ki Lee, Kwangha Lee, Min Ji Kim, Sun Mi Jang, Hae Jung Na, Seung Eon Song, Geewon Lee, Eun-Jung Jo, Mi-Hyun Kim, Ki Uk Kim and Hye-Kyung Park
    Citation: BMC Pulmonary Medicine 2015 15:166
    Content type: Research article Published on:

  14. Fluticasone furoate (FF)/vilanterol (VI) is a once daily (OD) inhaled corticosteroid/long-acting β2-agonist combination asthma therapy approved in Japan and the EU. FF/VI efficacy and safety data from asthma stud...

    Authors: Annette S. Gross, Caroline Goldfrad, Soichiro Hozawa, Mark H. James, Christine S. Clifton, Yutaro Sugiyama and Loretta Jacques
    Citation: BMC Pulmonary Medicine 2015 15:165
    Content type: Research article Published on:

  15. Biodegradable stents that disintegrate after a period of time are expected to be well tolerated and have advantages over other stents that are more commonly used in practice today. Polydioxanone is a biodegrad...

    Authors: Ludek Stehlik, Vladislav Hytych, Jana Letackova, Petr Kubena and Martina Vasakova
    Citation: BMC Pulmonary Medicine 2015 15:164
    Content type: Technical advance Published on:

  17. Idiopathic pulmonary fibrosis acute exacerbation (IPF-AE) constitutes IPF’s most devastating event, representing the unexpected superimposition of diffuse alveolar damage of unknown etiology. Guidelines recomm...

    Authors: Spyros A Papiris, Konstantinos Kagouridis, Likurgos Kolilekas, Andriana I Papaioannou, Aneza Roussou, Christina Triantafillidou, Katerina Baou, Katerina Malagari, Stylianos Argentos, Anastasia Kotanidou, Anna Karakatsani and Effrosyni D Manali
    Citation: BMC Pulmonary Medicine 2015 15:162
    Content type: Research article Published on:

  18. Persistent airway infection is a hallmark feature of cystic fibrosis (CF). However, increasingly it has been observed that non-classical pathogens may transiently infect CF lower airways. Streptococcus pyogenes (...

    Authors: Kate Skolnik, Austin Nguyen, Ranjani Somayaji, Christina S. Thornton, Barbara Waddell, Michael G. Surette, Harvey R. Rabin and Michael D. Parkins
    Citation: BMC Pulmonary Medicine 2015 15:161
    Content type: Research article Published on:

  19. Novel therapies need to be evaluated in normal clinical practice to allow a true representation of the treatment effectiveness in real-world settings.

    Authors: Ashley Woodcock, Nawar Diar Bakerly, John P. New, J. Martin Gibson, Wei Wu, Jørgen Vestbo and David Leather
    Citation: BMC Pulmonary Medicine 2015 15:160
    Content type: Study protocol Published on:

  20. Interstitial lung disease (ILD) associated with clinically amyopathic dermatomyositis (CADM-ILD) is often refractory and rapidly progressive. Although the anti-melanoma differentiation-associated gene 5 (anti-...

    Authors: Satoshi Ikeda, Machiko Arita, Mitsunori Morita, Satoshi Ikeo, Akihiro Ito, Fumiaki Tokioka, Maki Noyama, Kenta Misaki, Kenji Notohara and Tadashi Ishida
    Citation: BMC Pulmonary Medicine 2015 15:159
    Content type: Research article Published on:

  21. Pulmonary deterioration after B.cepacia complex (BCC) colonization has a heterogeneous pattern. The aim was to investigate the clinical outcome of BCC colonization in CF patients chronically colonized with P. aer...

    Authors: Tania Wrobel Folescu, Claudia Henrique da Costa, Renata Wrobel Folescu Cohen, Orlando Carlos da Conceição Neto, Rodolpho Mattos Albano and Elizabeth Andrade Marques
    Citation: BMC Pulmonary Medicine 2015 15:158
    Content type: Research article Published on:

  22. Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder partially resistant to glucocorticoids. A reduced histone deacetylase (HDAC) activity has been proposed to explain this resistance. Haemoph...

    Authors: Borja G. Cosío, Andreas Jahn, Amanda Iglesias, Hanaa Shafiek, Xavier Busquets and Alvar Agustí
    Citation: BMC Pulmonary Medicine 2015 15:157
    Content type: Research article Published on:

  23. Cardiovascular comorbidity in COPD is common and contributes to increased mortality. A few population-based studies indicate that ischemic electrocardiogram (ECG)-changes are more prevalent in COPD, while othe...

    Authors: Ulf Nilsson, Bengt Johansson, Berne Eriksson, Anders Blomberg, Bo Lundbäck and Anne Lindberg
    Citation: BMC Pulmonary Medicine 2015 15:156
    Content type: Research article Published on:

  24. Idiopathic pulmonary fibrosis (IPF) is a chronic, fibrotic interstitial lung disease of unknown origin. It has a median survival of three years but a wide range in survival rate which is difficult to predict a...

    Authors: Cathy Sampson, Ben Hope Gill, Nicholas Kim Harrison, Annmarie Nelson and Anthony Byrne
    Citation: BMC Pulmonary Medicine 2015 15:155
    Content type: Research article Published on:

  25. Asthma and COPD (chronic obstructive pulmonary disease) lead to persistent airway inflammation and are associated with lung cancer. The objective of the study was to assess the relationship between inhaled (IC...

    Authors: Zhi-Hong Jian, Jing-Yang Huang, Frank Cheau-Feng Lin, Oswald Ndi Nfor, Kai-Ming Jhang, Wen-Yuan Ku, Chien-Chang Ho, Chia-Chi Lung, Hui-Hsien Pan, Yu-Chiu Liang, Ming-Fang Wu and Yung-Po Liaw
    Citation: BMC Pulmonary Medicine 2015 15:154
    Content type: Research article Published on:

  26. To date, diagnosis of Primary Ciliary Dyskinesia (PCD) remains difficult and challenging. We systematically evaluated the diagnostic performance of nasal Nitric Oxide (nNO) measurement for the detection of PCD...

    Authors: Panayiotis Kouis, Stefania I. Papatheodorou and Panayiotis K. Yiallouros
    Citation: BMC Pulmonary Medicine 2015 15:153
    Content type: Research article Published on:

  27. F-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is increasingly used for the initial staging and restaging of lung cancer. Incidental gastrointestinal findings are often obs...

    Authors: Juliette Vella-Boucaud, Dimitri Papathanassiou, Olivier Bouche, Alain Prevost, Thibault Lestra, Sandra Dury, Hervé Vallerand, Jeanne-Marie Perotin, Claire Launois, Louis Boissiere, Mathilde Brasseur, François Lebargy and Gaëtan Deslee
    Citation: BMC Pulmonary Medicine 2015 15:152
    Content type: Research article Published on:

  28. The aim of this study was to examine the relationship between pulmonary exacerbations and physical activity (PA) in adults with cystic fibrosis (CF).

    Authors: Daniela Savi, Nicholas Simmonds, Marcello Di Paolo, Serena Quattrucci, Paolo Palange, Winston Banya, Nicholas S. Hopkinson and Diana Bilton
    Citation: BMC Pulmonary Medicine 2015 15:151
    Content type: Research article Published on:

  29. YKL-40 is an extracellular matrix glycoprotein with a significant role in tissue inflammation and remodeling. MIP-1a has chemotactic and pro-inflammatory properties, and is induced by YKL-40 in several lung di...

    Authors: Tonia Adamidi, Nikolaos Soulitzis, Eirini Neofytou, Savvas Zannetos, Andreas Georgiou, Kleomenis Benidis, Alexis Papadopoulos, Nikolaos M. Siafakas and Sophia E. Schiza
    Citation: BMC Pulmonary Medicine 2015 15:150
    Content type: Research article Published on:

  30. Pneumococcal pneumonia is the most common form of community-acquired pneumonia (CAP). Although a pneumococcal conjugate vaccine has contributed to a reduction in the incidence of pneumococcal pneumonia among o...

    Authors: Nobuhiro Akuzawa and Hiroshi Naito
    Citation: BMC Pulmonary Medicine 2015 15:149
    Content type: Research article Published on:

  31. Acute bronchiolitis is the commonest cause of hospitalisation in infancy. Currently management consists of supportive care and oxygen. A Cochrane review concluded that, “nebulised 3 % saline may significantly ...

    Authors: Chin Maguire, Hannah Cantrill, Daniel Hind, Mike Bradburn and Mark L. Everard
    Citation: BMC Pulmonary Medicine 2015 15:148
    Content type: Research article Published on:

  32. The course of disease for patients with idiopathic pulmonary fibrosis (IPF) is highly heterogeneous. Prognostic models rely on demographic and clinical characteristics and are not reproducible. Integrating dat...

    Authors: Yong Huang, Shwu-Fan Ma, Rekha Vij, Justin M. Oldham, Jose Herazo-Maya, Steven M. Broderick, Mary E. Strek, Steven R. White, D. Kyle Hogarth, Nathan K. Sandbo, Yves A. Lussier, Kevin F. Gibson, Naftali Kaminski, Joe G. N. Garcia and Imre Noth
    Citation: BMC Pulmonary Medicine 2015 15:147
    Content type: Research article Published on:

  33. The preferences of parents and children with asthma influence their ability to manage a child’s asthma and achieve good control. Potential differences between parents and adolescents with respect to specific p...

    Authors: Wendy J. Ungar, Anahita Hadioonzadeh, Mehdi Najafzadeh, Nicole W. Tsao, Sharon Dell and Larry D. Lynd
    Citation: BMC Pulmonary Medicine 2015 15:146
    Content type: Research article Published on:

  34. Increasing evidence suggests pharmacological treatments may impact on overall survival in Chronic Obstructive Pulmonary Disease (COPD) patients. Individual clinical trials are rarely powered to detect mortalit...

    Authors: David A Scott, Bethan Woods, Juliette C Thompson, James F Clark, Neil Hawkins, Mike Chambers, Bartolome R. Celli and Peter Calverley
    Citation: BMC Pulmonary Medicine 2015 15:145
    Content type: Research article Published on:

  35. Noninvasive ventilation (NIV) is used in critically ill patients with acute respiratory failure (ARF) to avoid endotracheal intubation. However, the impact of NIV use on ARF patient’s outcomes is still unclear...

    Authors: Thiago Domingos Corrêa, Paula Rodrigues Sanches, Lúbia Caus de Morais, Farah Christina Scarin, Eliézer Silva and Carmen Sílvia Valente Barbas
    Citation: BMC Pulmonary Medicine 2015 15:144
    Content type: Research article Published on:

  36. A strategy to reduce the number of smoking-related deaths is to encourage the involvement of health-care professionals in tobacco-use prevention activities and cessation counseling. Previous studies have shown...

    Authors: Pinar Pazarli Bostan, Canan Karaman Demir, Osman Elbek and Şule Akçay
    Citation: BMC Pulmonary Medicine 2015 15:143
    Content type: Research article Published on:

  37. Currently, little data is available about the management of asthma in the working population. The aim of this study was to describe asthma control and severity among workers according to current or previous al...

    Authors: Dorothée Provost, Yuriko Iwatsubo, Stéphanie Riviere, Maëlaïg Mevel, Alain Didier, Patrick Brochard, Ellen Imbernon and Chantal Raherison
    Citation: BMC Pulmonary Medicine 2015 15:142
    Content type: Research article Published on:

  38. Bronchiectasis is characterized by abnormal, permanent and irreversible dilatation of the bronchi, usually responsible for daily symptoms and frequent respiratory complications. Many causes have been identifie...

    Authors: Sandra Dury, Charlotte Colosio, Isabelle Etienne, Dany Anglicheau, Elodie Merieau, Sophie Caillard, Joseph Rivalan, Eric Thervet, Marie Essig, François Babinet, Jean-François Subra, Olivier Toubas, Philippe Rieu, Claire Launois, Jeanne-Marie Perotin-Collard, François Lebargy…
    Citation: BMC Pulmonary Medicine 2015 15:141
    Content type: Research article Published on:

  39. Idiopathic pulmonary fibrosis (IPF) is an interstitial fibrotic lung disease of unknown origin and without effective therapy characterized by deposition of extracellular matrix by activated fibroblasts in the ...

    Authors: Stephanie A. Matthes, Thomas J. LaRouere, Jeffrey C. Horowitz and Eric S. White
    Citation: BMC Pulmonary Medicine 2015 15:140
    Content type: Research article Published on:

  40. Impaired lung function and insulin resistance have been associated and thereby have also been indicated to be powerful predictors of cardiovascular mortality. Therefore, the co-existence of insulin resistance ...

    Authors: Gul Sagun, Canan Gedik, Esra Ekiz, Engin Karagoz, Mumtaz Takir and Aytekin Oguz
    Citation: BMC Pulmonary Medicine 2015 15:139
    Content type: Research article Published on:

  41. Epidemic P. aeruginosa (ePA) infections are common in cystic fibrosis (CF) and have been associated with accelerated clinical decline. Factors associated with ePA are unclear, and evidence based infection control...

    Authors: R. Somayaji, B. Waddell, M. L. Workentine, M. G. Surette, N. P. Brager, H. R. Rabin and M. D. Parkins
    Citation: BMC Pulmonary Medicine 2015 15:138
    Content type: Research article Published on:

  42. Air pollution is associated with a high burden or morbidity and mortality, but exposure cannot be quantified rapidly or cheaply. The particulate burden of macrophages from induced sputum may provide a biomarke...

    Authors: Hannah Jary, Jamie Rylance, Latifa Patel, Stephen B. Gordon and Kevin Mortimer
    Citation: BMC Pulmonary Medicine 2015 15:137
    Content type: Research article Published on:

  43. In some patients with COPD, the disease is characterized by exacerbations. Severe exacerbations warrant a hospitalization, with prolonged detrimental effects on physical activity. Interventions after an exacer...

    Authors: Miek Hornikx, Heleen Demeyer, Carlos Augusto Camillo, Wim Janssens and Thierry Troosters
    Citation: BMC Pulmonary Medicine 2015 15:136
    Content type: Research article Published on:

  45. Evidence suggests that individuals with interstitial lung abnormalities (ILA) on a chest computed tomogram (CT) may have an increased risk to develop a clinically significant interstitial lung disease (ILD). A...

    Authors: Corrine R. Kliment, Tetsuro Araki, Tracy J. Doyle, Wei Gao, Josée Dupuis, Jeanne C. Latourelle, Oscar E. Zazueta, Isis E. Fernandez, Mizuki Nishino, Yuka Okajima, James C. Ross, Raúl San José Estépar, Alejandro A. Diaz, David J. Lederer, David A. Schwartz, Edwin K. Silverman…
    Citation: BMC Pulmonary Medicine 2015 15:134
    Content type: Research article Published on:

  46. The Streptococcus anginosus group (SAG) play important roles in respiratory infections. It is ordinarily difficult to distinguish them from contaminations as the causative pathogens of respiratory infections beca...

    Authors: Shingo Noguchi, Kazuhiro Yatera, Toshinori Kawanami, Kei Yamasaki, Keisuke Naito, Kentaro Akata, Ikuko Shimabukuro, Hiroshi Ishimoto, Chiharu Yoshii and Hiroshi Mukae
    Citation: BMC Pulmonary Medicine 2015 15:133
    Content type: Research article Published on:

  47. Although it has been suggested that a high level of thymidylate synthase (TYMS) gene expression in malignant tumors is related to reduced sensitivity to the antifolate drug pemetrexed, no direct evidence for such...

    Authors: Cristina Chamizo, Sandra Zazo, Manuel Dómine, Ion Cristóbal, Jesús García-Foncillas, Federico Rojo and Juan Madoz-Gúrpide
    Citation: BMC Pulmonary Medicine 2015 15:132
    Content type: Research article Published on:

  48. Mycobacterium lentiflavum is rarely isolated in respiratory tract samples from cystic fibrosis patients. We herein describe an unusually high prevalence of M. lentiflavum in such patients.

    Authors: Michael Phelippeau, Jean-Christophe Dubus, Martine Reynaud-Gaubert, Carine Gomez, Nathalie Stremler le Bel, Marielle Bedotto, Elsa Prudent and Michel Drancourt
    Citation: BMC Pulmonary Medicine 2015 15:131
    Content type: Research article Published on:

  49. Although anti-neutrophil cytoplasmic antibodies [ANCA] are frequently found in patients diagnosed with idiopathic pulmonary fibrosis [IPF], current guidance does not recommend serologic testing for vasculitis.

    Authors: Marc Pineton de Chambrun, Hilario Nunes, Isabelle Brochériou and Alexandre Hertig
    Citation: BMC Pulmonary Medicine 2015 15:130
    Content type: Case report Published on:

  50. Atrial fibrillation (AF) can be treated with percutaneous catheter ablation procedures into the left atrium. Pulmonary veins stenosis (PV) stenosis is a severe complication of this procedure.

    Authors: Savino Spadaro, Sara Saturni, Delia Cadorin, Maria V. Colamussi, Matteo Bertini, Roberto Galeotti, Riccardo Cappato, Franco Ravenna and Carlo A. Volta
    Citation: BMC Pulmonary Medicine 2015 15:128
    Content type: Case report Published on:
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BMC Pulmonary Medicine

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