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  1. Research article

    Latin America validation of FACED score in patients with bronchiectasis: an analysis of six cohorts

    The FACED score is an easy-to-use multidimensional grading system that has demonstrated an excellent prognostic value for mortality in patients with bronchiectasis. A Spanish group developed the score but no m...

    Rodrigo Athanazio, Mônica Corso Pereira, Georgina Gramblicka, Fernando Cavalcanti-Lundgren, Mara Fernandes de Figueiredo, Francisco Arancibia, Samia Rached, David de la Rosa, Luis Máiz-Carro, Rosa Girón, Casilda Olveira, Concepción Prados and Miguel Angel Martinez-Garcia

    BMC Pulmonary Medicine 2017 17:73

    Published on: 26 April 2017

  2. Research article

    Exploratory analysis of the neutrophil to lymphocyte ratio in patients with pulmonary arterial hypertension

    Chronic inflammation emerges as a feature of the pathogenesis of pulmonary arterial hypertension (PAH) in experimental models. Alterations of circulating cell subsets have been observed in patients with PAH. W...

    Lars Harbaum, Kaaja M. Baaske, Marcel Simon, Tim Oqueka, Christoph Sinning, Antonia Glatzel, Nicole Lüneburg, Karsten Sydow, Carsten Bokemeyer and Hans Klose

    BMC Pulmonary Medicine 2017 17:72

    Published on: 26 April 2017

  3. Research article

    The utility of electron microscopy in detecting asbestos fibers and particles in BALF in diffuse lung diseases

    In patients with diffuse lung diseases, differentiating occupational lung diseases from other diseases is clinically important. However, the value of assessing asbestos and particles in bronchoalveolar lavage ...

    Takashi Kido, Yasuo Morimoto, Kazuhiro Yatera, Hiroshi Ishimoto, Takaaki Ogoshi, Keishi Oda, Kei Yamasaki, Toshinori Kawanami, Shohei Shimajiri and Hiroshi Mukae

    BMC Pulmonary Medicine 2017 17:71

    Published on: 21 April 2017

  4. Research article

    Water-pipe smoke condensate increases the internalization of Mycobacterium Bovis of type II alveolar epithelial cells (A549)

    Tuberculosis (TB) is a major global health problem, and there is an association between tobacco smoke and TB. Water pipe smoking has become an increasing problem not only in Middle Eastern countries but also g...

    Esmaeil Mortaz, Shamila D. Alipoor, Masoud Movassaghi, Mohammad Varahram, Jahangir Ghorbani, Gert Folkerts, Johan Garssen and Ian M. Adcock

    BMC Pulmonary Medicine 2017 17:68

    Published on: 21 April 2017

  5. Research article

    Asthma–COPD overlap syndrome (ACOS) in primary care of four Latin America countries: the PUMA study

    Asthma–COPD overlap syndrome (ACOS) prevalence varies depending on the studied population and definition criteria. The prevalence and clinical characteristics of ACOS in an at-risk COPD primary care population...

    Maria Montes de Oca, Maria Victorina Lopez Varela, Maria E. Laucho-Contreras, Alejandro Casas, Eduardo Schiavi and Juan Carlos Mora

    BMC Pulmonary Medicine 2017 17:69

    Published on: 21 April 2017

  6. Research article

    Co-colonisation with Aspergillus fumigatus and Pseudomonas aeruginosa is associated with poorer health in cystic fibrosis patients: an Irish registry analysis

    Pulmonary infection is the main cause of death in cystic fibrosis (CF). Aspergillus fumigatus (AF) and Pseudomonas aeruginosa (PA) are the most prevalent fungal and bacterial pathogens isolated from the CF airway...

    Emma Reece, Ricardo Segurado, Abaigeal Jackson, Siobhán McClean, Julie Renwick and Peter Greally

    BMC Pulmonary Medicine 2017 17:70

    Published on: 21 April 2017

  7. Research article

    Efficacy of budesonide/formoterol maintenance and reliever therapy compared with higher-dose budesonide as step-up from low-dose inhaled corticosteroid treatment

    Asthma management may involve a step up in treatment when symptoms are not well controlled. We examined whether budesonide/formoterol maintenance and reliever therapy (MRT) is as effective as higher, fixed-dos...

    Christine R. Jenkins, Göran Eriksson, Eric D. Bateman, Helen K. Reddel, Malcolm R. Sears, Magnus Lindberg and Paul M. O’Byrne

    BMC Pulmonary Medicine 2017 17:65

    Published on: 20 April 2017

  8. Research article

    Impact of lymphocyte differential count > 15% in BALF on the mortality of patients with acute exacerbation of chronic fibrosing idiopathic interstitial pneumonia

    Chronic fibrosing idiopathic interstitial pneumonia (CFIIP) has a potential risk of acute exacerbation (AE). However, the usefulness of cellular analysis of bronchoalveolar lavage fluid (BALF) has never been e...

    Reoto Takei, Machiko Arita, Shogo Kumagai, Yuhei Ito, Maki Noyama, Fumiaki Tokioka and Tadashi Ishida

    BMC Pulmonary Medicine 2017 17:67

    Published on: 20 April 2017

  9. Research article

    Penicillin treatment for patients with Community-Acquired Pneumonia in Denmark: a retrospective cohort study

    Community-acquired pneumonia (CAP) is a severe infection, with high mortality. Antibiotic strategies for CAP differ across Europe.

    Gertrud Baunbæk Egelund, Andreas Vestergaard Jensen, Stine Bang Andersen, Pelle Trier Petersen, Bjarne Ørskov Lindhardt, Christian von Plessen, Gernot Rohde and Pernille Ravn

    BMC Pulmonary Medicine 2017 17:66

    Published on: 20 April 2017

  10. Research article

    Effect of pulmonary arteriovenous malformations on the mechanical properties of the lungs

    Pulmonary arteriovenous malformations (PAVMs) are present in approximately 15–50% individuals with hereditary hemorrhagic telangiectasia (HHT). They may be isolated but more often are multiple. The goal of thi...

    Cécile Rotenberg, Marcel Bonay, Mostafa El Hajjam, Sandra Blivet, Alain Beauchet, Pascal Lacombe and Thierry Chinet

    BMC Pulmonary Medicine 2017 17:64

    Published on: 19 April 2017

  11. Research article

    Validity and reliability of fluoroscopy for digital radiography: a new way to evaluate diaphragmatic mobility

    Fluoroscopy is considered the most accurate method to evaluate the diaphragm, yet most existing methods for measuring diaphragmatic mobility using fluoroscopy are complex. To assess the validity and reliabilit...

    Bruna Estima Leal, Márcia Aparecida Gonçalves, Liseane Gonçalves Lisboa, Larissa Martins Schmitz Linné, Michelle Gonçalves de Souza Tavares, Wellington Pereira Yamaguti and Elaine Paulin

    BMC Pulmonary Medicine 2017 17:62

    Published on: 17 April 2017

  12. Research article

    A new clinical algorithm scoring for management of suspected foreign body aspiration in children

    Foreign Body Aspiration (FBA) is a serious problem in children and delays in diagnosis and management can be devastating. The history is often vague, with subtle physical and chest radiograph abnormalities. Th...

    Ibrahim A. Janahi, Shabina Khan, Prem Chandra, Noora Al-Marri, Ammar Saadoon, Lolwa Al-Naimi, Maryam Al-Thani and William Greer

    BMC Pulmonary Medicine 2017 17:61

    Published on: 13 April 2017

  13. Research article

    Hemosiderin in sputum macrophages may predict infective exacerbations of chronic obstructive pulmonary disease: a retrospective observational study

    Infective exacerbations of COPD are common and are accompanied by neutrophilic bronchitis in sputum. Increased respiratory iron content has been associated with respiratory tract infection, though it is unclea...

    Sindu Mohan, Terence Ho, Melanie Kjarsgaard, Katherine Radford, A. S. M. Borhan, Lehana Thabane and Parameswaran Nair

    BMC Pulmonary Medicine 2017 17:60

    Published on: 12 April 2017

  14. Research article

    Electromagnetic navigation bronchoscopy to access lung lesions in 1,000 subjects: first results of the prospective, multicenter NAVIGATE study

    Electromagnetic navigation bronchoscopy (ENB) is an image-guided, minimally invasive approach that uses a flexible catheter to access pulmonary lesions.

    Sandeep J. Khandhar, Mark R. Bowling, Javier Flandes, Thomas R. Gildea, Kristin L. Hood, William S. Krimsky, Douglas J. Minnich, Septimiu D. Murgu, Michael Pritchett, Eric M. Toloza, Momen M. Wahidi, Jennifer J. Wolvers and Erik E. Folch

    BMC Pulmonary Medicine 2017 17:59

    Published on: 11 April 2017

  15. Research article

    Healthcare burden of pulmonary hypertension owing to lung disease and/or hypoxia

    Group 3 pulmonary hypertension (PH) encompasses PH owing to lung diseases and/or hypoxia. Treatment patterns, healthcare resource use, and economic burden to US payers of Group 3 PH patients were assessed.

    Gustavo A. Heresi, David M. Platt, Wenyi Wang, Christine H. Divers, Vijay N. Joish, Simon A. Teal and Justin S. Yu

    BMC Pulmonary Medicine 2017 17:58

    Published on: 11 April 2017

  16. Research article

    A burden of rare variants in BMPR2 and KCNK3 contributes to a risk of familial pulmonary arterial hypertension

    Pulmonary arterial hypertension (PAH) is a severe lung disease with only few effective treatments available. Familial cases of PAH are usually recognized as an autosomal dominant disease, but incomplete penetr...

    Koichiro Higasa, Aiko Ogawa, Chikashi Terao, Masakazu Shimizu, Shinji Kosugi, Ryo Yamada, Hiroshi Date, Hiromi Matsubara and Fumihiko Matsuda

    BMC Pulmonary Medicine 2017 17:57

    Published on: 7 April 2017

  17. Research article

    A prospective observational study to evaluate the effect of social and personality factors on continuous positive airway pressure (CPAP) compliance in obstructive sleep apnoea syndrome

    Compliance with CPAP treatment for OSAS is not reliably predicted by the severity of symptoms or physiological variables. We examined a range of factors which could be measured before CPAP initiation to look f...

    Atul Gulati, Masood Ali, Mike Davies, Tim Quinnell and Ian Smith

    BMC Pulmonary Medicine 2017 17:56

    Published on: 22 March 2017

  18. Research article

    Obstructive sleep apnoea accelerates FEV1 decline in asthmatic patients

    Although the prevalence of both obstructive sleep apnoea (OSA) and asthma are both increasing, little is known about the impact of OSA on the natural history of lung function in asthmatic patients.

    Tsai-Yu Wang, Yu-Lun Lo, Shu-Min Lin, Chien-Da Huang, Fu-Tasi Chung, Horng-Chyuan Lin, Chun-Hua Wang and Han-Pin Kuo

    BMC Pulmonary Medicine 2017 17:55

    Published on: 21 March 2017

  19. Research article

    Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

    Epigenetic variations in peripheral blood have potential as biomarkers for disease. This systematic review assesses the association of lung function and chronic obstructive pulmonary disease (COPD) with DNA me...

    Matthew Machin, André F. S. Amaral, Matthias Wielscher, Faisal I. Rezwan, Medea Imboden, Marjo-Riitta Jarvelin, Ian M. Adcock, Nicole Probst-Hensch, John W. Holloway and Deborah L. Jarvis

    BMC Pulmonary Medicine 2017 17:54

    Published on: 20 March 2017

  20. Erratum

    Erratum to: Effects of periodontal treatment on exacerbation frequency and lung function in patients with chronic periodontitis: study protocol of a 1-year randomized controlled trial

    Sergio dos Santos Romero, Erika Horácio Pinto, Priscila Larcher Longo, Simone Dal Corso, Fernanda Cordoba Lanza, Rafael Stelmach, Samia Zahi Rached, Adriana Lino-dos-Santos-Franco, Marcia Pinto Alves Mayer, Sandra Kalil Bussadori, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari and Anna Carolina Ratto Tempestini Horliana

    BMC Pulmonary Medicine 2017 17:51

    Published on: 14 March 2017

    The original article was published in BMC Pulmonary Medicine 2017 17:23

  21. Research article

    Switch of noninvasive ventilation (NIV) to continuous positive airway pressure (CPAP) in patients with obesity hypoventilation syndrome: a pilot study

    Obesity is a major worldwide public health issue. The main respiratory complication stemming from obesity is obesity hypoventilation syndrome (OHS). Most of the OHS patients diagnosed during an exacerbation ar...

    Sarah Orfanos, Dany Jaffuel, Christophe Perrin, Nicolas Molinari, Pascal Chanez and Alain Palot

    BMC Pulmonary Medicine 2017 17:50

    Published on: 14 March 2017

  22. Study protocol

    Effectiveness of pulmonary rehabilitation for patients with asthma: study protocol of a randomized controlled trial (EPRA)

    Asthma patients are enrolled in multimodal pulmonary rehabilitation (PR) programs. However, available data for the effectiveness of PR in asthma are sparse. Therefore, the primary aim of this randomized contro...

    Konrad Schultz, Hildegard Seidl, Danijel Jelusic, Rupert Wagner, Michael Wittmann, Hermann Faller, Dennis Nowak and Michael Schuler

    BMC Pulmonary Medicine 2017 17:49

    Published on: 9 March 2017

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