Table 1 Baseline characteristics
From: Effect of obesity on constant workrate exercise in hyperinflated men with COPD
Normal BMI (NBMI), n = 84 | Overweight (OW), n = 130 | Obese (OB), n = 64 | p | ||||||
|---|---|---|---|---|---|---|---|---|---|
NBMI | OW | NBMI | |||||||
Mean | (SD) | Mean | (SD) | Mean | (SD) | vs. | vs. | vs. | |
OW | OB | OB | |||||||
Age, years | 61.4 | (7.2) | 62.6 | (6.4) | 61.6 | (6.6) | - | - | - |
Tobacco exposure, Pack*years | 52.3 | (25.7) | 59.0 | (29.6) | 55.8 | (25.5) | - | - | - |
BMI, kg*m-2 | 22.5 | (1.7) | 27.3 | (1.5) | 33.4 | (3.1) | 0.0001 | 0.0001 | 0.0001 |
Ideal weight, kg | 77.6 | (0.6) | 77.9 | (0.5) | 76.9 | (0.7) | - | - | - |
FEV1, L | 1.31 | (0.39) | 1.35 | (0.45) | 1.42 | (0.49) | - | - | - |
% predicted | 40 | (11) | 42 | (13) | 44 | (14) | - | - | - |
FVC, L | 3.09 | (0.81) | 3.04 | (0.80) | 2.89 | (0.78) | - | - | - |
% predicted | 75 | (18) | 74 | (17) | 71 | (17) | - | - | - |
FEV1/FVC | 42.9 | (8.6) | 44.5 | (10.1) | 48.9 | (11.7) | - | 0.05 | 0.01 |
TLC | 8.38 | (1.27) | 8.04 | (1.27) | 7.79 | (1.14) | - | - | 0.05 |
% predicted | 121 | (17) | 116 | (17) | 114 | (14) | - | - | 0.05 |
IC, L | 2.46 | (0.57) | 2.51 | (0.60) | 2.50 | (0.65) | - | - | - |
% predicted | 73 | (15) | 75 | (17) | 76 | (18) | - | - | - |
IC/TLC | 30 | (7) | 31 | (7) | 32 | (8) | - | - | - |
FRC, L | 6.06 | (1.16) | 5.66 | (1.10) | 5.40 | (1.05) | 0.05 | - | 0.001 |
% predicted | 170 | (31) | 158 | (29) | 152 | (27) | 0.05 | - | 0.001 |
RV, L | 5.02 | (1.26) | 4.63 | (1.16) | 4.53 | (0.99) | - | - | 0.05 |
% predicted | 208 | (50) | 188 | (50) | 185 | (46) | 0.05 | - | 0.05 |
DLCO, ml*mmHg-1*min-1 | 15.4 | (5.1) | 16.2 | (5.5) | 19.2 | (6.6) | - | 0.01 | 0.001 |
% predicted | 46 | (22) | 48 | (24) | 59 | (27) | - | 0.01 | 0.01 |
Incremental exercise test | |||||||||
Peak VO2, L*min-1 | 1.204 | (0.385) | 1.375 | (0.379) | 1.550 | (0.450) | 0.01 | 0.05 | 0.0001 |
ml*kg-1*min-1 | 17.5 | (5.3) | 16.3 | (4.0) | 15.4 | (4.4) | - | - | 0.05 |
% predicted | 50 | (15) | 57 | (14) | 65 | (18) | 0.01 | 0.01 | 0.0001 |
ml*kgideal weight -1*min-1 | 15.5 | (4.7) | 17.5 | (4.8) | 20.2 | (5.6) | 0.01 | 0.01 | 0.0001 |
Peak VE, L*min-1 | 44.5 | (13.8) | 48.5 | (13.5) | 49.2 | (14.3) | - | - | - |
% MVV | 100.3 | (32.2) | 108.6 | (32.9) | 108.0 | (39.1) | - | - | - |
Peak power, W | 82.8 | (28.1) | 90.4 | (26.7) | 93.2 | (35.1) | - | - | - |
% predicted | 45 | (14) | 50 | (15) | 52 | (18) | - | - | 0.05 |