Variables | Groups | Initial | 1 hour | 3 hours | 12 hours | P |
---|---|---|---|---|---|---|
GSC | BiPAP S/T | 8.3 ± 1.4 | 9.7 ± 2 | 12 ± 1.5 | 13 ± 1 | .00001* |
BiPAP S/T + AVAPS | 8.3 ± 1.6 | 11 ± 1 | 14.1 ± 0.8 | 15 ± 0 | ||
pH | BiPAP S/T | 7.28 ± 0.02 | 7.30 ± 0.05 | 7.31 ± 0.11 | 7.32 ± 0.12 | .31 |
BiPAP S/T + AVAPS | 7.29 ± 0.03 | 7.34 ± 0.04 | 7.37 ± 0.11 | 7.37 ± 0.08 | ||
pCO 2 | BiPAP S/T | 64.8 ± 9.1 | 58.3 ± 8.7 | 53.2 ± 9 | 50.1 ± 6.5 | .03* |
BiPAP S/T + AVAPS | 63 ± 16.3 | 50.7 ± 11.2 | 45.4 ± 7.9 | 43.6 ± 6.5 | ||
PO 2 | BiPAP S/T | 66.6 ± 12.7 | 83.1 ±17.8 | 75.3 ± 26.7 | 79.7 ± 16.2 | .31 |
BiPAP S/T + AVAPS | 71.5 ± 16.8 | 78 ± 19.1 | 87.5 ± 11.5 | 87.4 ± 18 | ||
HCO 3 | BiPAP S/T | 26.9 ± 5.7 | 24.4 ± 6.3 | 25.8 ± 4.6 | 27.1 ± 4.3 | .19 |
BiPAP S/T + AVAPS | 24.4 ± 5 | 22.5 ± 3.5 | 23.7 ± 5.2 | 24.6 ± 4.3 | ||
Base excess | BiPAP S/T | 3.3 ± 6.9 | 0.1 ± 7 | 10.3 ± 31.7 | 3.6 ± 4.7 | .06 |
BiPAP S/T + AVAPS | −1.8 ± 5.7 | 2.8 ± 18 | 5.7 ± 19.8 | 2.9 ± 9 | ||
Systolic blood pressure | BiPAP S/TS/T | 125.1 ± 10 | 124.2 ± 12.6 | 130.4 ± 14.3 | 130.6 ± 13.8 | .29 |
BiPAP S/T + AVAPS | 125.9 ± 17.3 | 131.1 ± 21.1 | 129.9 ± 18.4 | 123.5 ± 16.9 | ||
Diastolic blood pressure | BiPAP S/T | 73.9 ± 9.8 | 72.2 ± 8.4 | 71.8 ± 9.4 | 73.7 ± 10.7 | .07 |
BiPAP S/T + AVAPS | 65.5 ± 11.6 | 69.8 ± 11.6 | 70.1 ± 11.1 | 65.9 ± 8.5 | ||
Heart rate | BiPAP S/T | 86.7 ± 9.1 | 82.1 ± 7.8 | 80.4 ± 5.8 | 79.1 ± 5.5 | .07 |
BiPAP S/T + AVAPS | 82 ± 10.9 | 82.5 ± 9.9 | 72.8 ± 14.1 | 72. ± 11.2 | ||
Respiratory rate | BiPAP S/T | 27.9 ± 5.6 | 23.2 ± 3.5 | 21 ± 2.6 | 20 ± 1.61 | .01* |
BiPAP S/T + AVAPS | 29 ± 6.9 | 17.4 ± 3.2 | 18.5 ± 3.6 | 19.9 ± 5.1 | ||
Maximum delivered IPAP received | BiPAP S/T | 12.3 ± 0.9 | 12.6 ± 0.9 | 14.3 ± 0.8 | 14.7 ± 1 | .005* |
BiPAP S/T + AVAPS | 19.8 ± 2.2 | 18.3 ± 2.3 | 18 ± 2.6 | 17 ± 2.3 | ||
EPAP | BiPAP S/T | 5.9 ± 0.3 | 6 ± 0 | 6 ± 0 | 6 ± 0 | .32 |
BiPAP S/T + AVAPS | 6 ± 0 | 6 ± 0 | 5.9 ± 0.3 | 5.9 ± 0.3 | ||
Minute volume | BiPAP S/T | 8.7 ± 3.1 | 9.2 ± 2.2 | 10.8 ± 1.4 | 10.6 ± 1.4 | .17 |
BiPAP S/T + AVAPS | 8.5 ± 2.2 | 10.5 ± 2.5 | 11.5 ± 3.1 | 11.6 ± 1.8 | ||
Exhaled tidal volume | BiPAP S/T | 304 ± 60.6 | 400.5 ± 73.9 | 519 ± 61.4 | 531.1± 63.6 | .01* |
BiPAP S/T + AVAPS | 298.6 ± 54.3 | 606.3 ± 75.4 | 626.3 ± 77.6 | 617.6 ± 77.4 | ||
Leak | BiPAP S/T | 9.3 ± 3.8 | 21 ± 2 | 11 ± 3 | 11 ± 3.4 | .20 |
BiPAP S/T + AVAPS | 14 ± 11.2 | 18.3 ± 3.7 | 17.5 ± 16 | 17.5 ± 16 |