Table 3 Previous clinical and functional respiratory characteristics of all patients with asthma who died, by the degree of certainty of the diagnosis of asthma
From: “Causes of death in asthma, COPD and non-respiratory hospitalized patients: a multicentric study”
All (n = 82) | Asthma high certainty*(n = 26) | Asthma lower certainty*(n = 56) | Value of p | |
|---|---|---|---|---|
Age mean (SD) | 75 (15) | 70 (15) | 78 (15) | 0.061 |
Sex | ||||
– men | 52 | 23.1 | 21.4 | 0.869 |
– women | 47 | 76.9 | 78.6 | |
BMI mean (SD) | 23.7 (6) | 27.8 (7.2) | 27.5 (7.1) | 0.900 |
Hospitalizations due to asthma. n (%) | ||||
– Patients admitted | 26 (48.1) | 10 (38.5%) | 16 (28.6%) | 0.838 |
– Number of admissions per patient | 2.03 (1.8) | 2.83 (2.3) | 1.55 (1.3) | |
Asthma control (GINA), n (%) | ||||
Uncontrolled | 41 (59.4) | 14 (58.3) | 27 (60) | 0.791 |
Partly controlled | 18 (26.1) | 6 (25.0) | 12 (26.7) | |
Controlled | 10 (14.5) | 4 (16.7) | 6 (13.3) | |
GINA severity, n (%) | ||||
Intermittent, | 17 (28.8) | 3 (14.3) | 14 (36.8) | 0.075 |
Persistent, mild | 13 (22.0) | 2 (9.5) | 11 (28.9) | |
Persistent, moderate | 21 (35.4) | 11 (52.4) | 10 (26.4) | |
Persistent, severe | 8 (13.6) | 5 (23.8) | 3 (7.9) | |
Spirometry, mean (SD) | ||||
– FEV1, ml | 1.215 (767) | 1453 (739) | 907 (709) | 0.692 |
– FEV1,% | 64.4 (23) | 63.2(22.4) | 66.5 (25.2) | |
Previous maintenance treatment, n (%) | ||||
– LABA + ICS | 19 (26.7) | 12 (46.1) | 7 (15.6) | 0.122 |
– LABA + ICS + LTRAs | 13 (18.3) | 8 (30.8) | 5 (11.1) | |
– No treatment | 12 (16.9) | 3 (11.5) | 9 (20) | |
– Short-acting β2-adrenergic agonist | 10 (14.1) | 2 (7.8) | 8 (17.8) | |
– LTRAs | 9 (12.7) | 0 | 9 (20) | |
– LABA+ICS+oral corticosteroids | 3 (4.2) | 0 | 3 (6.7) | |
– Other: | ||||
– Ipratropium bromide | 2 (2.8) | 0 | 2 (4.4) | |
– LABA only | 2 (2.8) | 1 (3.8) | 1 (2.2) | |
– ICS only | 1 (1.4) | 0 | 1 (2.2) |